TH50758A - Methods for preparation 5- (1- piperashinil) benzofuran-2-carboxamide With emulation Catalyzed by transition metals - Google Patents
Methods for preparation 5- (1- piperashinil) benzofuran-2-carboxamide With emulation Catalyzed by transition metalsInfo
- Publication number
- TH50758A TH50758A TH1004662A TH0001004662A TH50758A TH 50758 A TH50758 A TH 50758A TH 1004662 A TH1004662 A TH 1004662A TH 0001004662 A TH0001004662 A TH 0001004662A TH 50758 A TH50758 A TH 50758A
- Authority
- TH
- Thailand
- Prior art keywords
- carboxamide
- benzofuran
- preparation
- catalyzed
- piperashinil
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 3
- QHKJIJXBJCOABP-UHFFFAOYSA-N 1-benzofuran-2-carboxamide Chemical compound C1=CC=C2OC(C(=O)N)=CC2=C1 QHKJIJXBJCOABP-UHFFFAOYSA-N 0.000 title abstract 3
- 229910052723 transition metal Inorganic materials 0.000 title abstract 2
- 150000003624 transition metals Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims 2
- MKKSTJKBKNCMRV-UHFFFAOYSA-N 5-bromo-2-hydroxybenzaldehyde Chemical compound OC1=CC=C(Br)C=C1C=O MKKSTJKBKNCMRV-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000004185 ester group Chemical group 0.000 claims 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- -1 5-bromosalicylal Chemical class 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
Abstract
DC60 (10/03/53) กรรมวิธีสำหรับการเตรียม 5-(1-ไพเพอราซินิล)เบนโซฟิวแรน-2-คาร์บอกซาไมด์ ที่ซึ่ง, เป็น ขั้นตอนอินเตอร์มีเ ดียท, 5-โบรโมซาลิไซลาลดีไฮด์ หรือหนึ่งของอนุพันธ์ของมัน ถูกทำปฏิกิริยาใน การเอมิเนชั่นแบบเร่งปฏิกิริยาด้วยโลหะท รานซิสชั่น กับ R2- ไพเพอราซีน, ที่ซึ่ง R2 เป็นดังระบุไว้ ใน ข้อถือสิทธิ 1 กรรมวิธีสำหรับการเตรียม 5-(1-ไพเพอราซินิล)เบนโซฟิวแรน-2-คาร์บอกซาไมด์ ที่ซึ่ง, เสมือนเป็นขั้นตอนอินเตอร์มีเ ดียท, 5-โบรโมซาลิไซลาลดีไฮด์ หรือหนึ่งของอนุพันธ์ของมัน ถูกทำ ปฏิกิริยาในการเอมิเนชั่นแบบเร่งปฏิกิริยาด้วยโลหะท รานซิสชั่น กับ R2- ไพเพอราซีน, ที่ซึ่ง R2 เป็นดัง ระบุไว้ ในข้อถือสิทธิ 1 สิทธิบัตรยา DC60 (10/03/53) Process for preparation 5- (1-pipersinil) benzofuran-2-carboxamide where, is an intermeat step, 5-bromosalicylal. Formaldehyde Or one of its derivatives. Was reacted in Transition metal catalytic emission with R2-piperazine, where R2 is stated in claim 1. 5- (1-pipersinil) benzofuran-2-carboxamide where, as an intermeat step, 5-bromosalicila Aldehyde Or one of its derivatives was reacted in transition metal-catalyzed emission to R2-piperazine, where R2 is stated in Claim 1 Patent Drug.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH50758A true TH50758A (en) | 2002-04-29 |
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