TH4001B - Two substances are combined to form a foam. A foaming mixture against histamine H2, which contains it, and its preparation. - Google Patents
Two substances are combined to form a foam. A foaming mixture against histamine H2, which contains it, and its preparation.Info
- Publication number
- TH4001B TH4001B TH8701000034A TH8701000034A TH4001B TH 4001 B TH4001 B TH 4001B TH 8701000034 A TH8701000034 A TH 8701000034A TH 8701000034 A TH8701000034 A TH 8701000034A TH 4001 B TH4001 B TH 4001B
- Authority
- TH
- Thailand
- Prior art keywords
- mixture
- citrate
- approx
- acid
- preparation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 8
- 238000005187 foaming Methods 0.000 title claims abstract 4
- 238000002360 preparation method Methods 0.000 title claims abstract 3
- 239000000126 substance Substances 0.000 title claims abstract 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001340 histamine Drugs 0.000 title abstract 2
- 239000006260 foam Substances 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract 12
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims abstract 4
- 239000003513 alkali Substances 0.000 claims abstract 4
- 238000000034 method Methods 0.000 claims abstract 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims abstract 3
- 239000002253 acid Substances 0.000 claims abstract 3
- 229910052751 metal Inorganic materials 0.000 claims abstract 3
- 239000002184 metal Substances 0.000 claims abstract 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims abstract 2
- 230000001458 anti-acid effect Effects 0.000 claims abstract 2
- 239000001569 carbon dioxide Substances 0.000 claims abstract 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract 2
- 229940001468 citrate Drugs 0.000 claims 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 1
- 235000019262 disodium citrate Nutrition 0.000 claims 1
- 239000002526 disodium citrate Substances 0.000 claims 1
- 229940079896 disodium hydrogen citrate Drugs 0.000 claims 1
- CEYULKASIQJZGP-UHFFFAOYSA-L disodium;2-(carboxymethyl)-2-hydroxybutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(O)(C(=O)O)CC([O-])=O CEYULKASIQJZGP-UHFFFAOYSA-L 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 239000004088 foaming agent Substances 0.000 claims 1
- 239000008240 homogeneous mixture Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Abstract
สารสองชนิดรวมกันที่เกิดเป็นฟองได้ประกอบด้วยส่วนผสมทางเภสัชกรรมและกรรมวิธีสำหรับเตรียมสารสองชนิดรวมกันดังกล่าว ทำโดยปฏิกิริยาระหว่างกรดซิทริกกับโลหะแอลคาไลคาร์บอเนท หรือไบคาร์บอเนท/สารผสมจะเกิดปฏิกิริยาพรัอมกับปล่อย คาร์บอนไดออกไซด์ออกมาจนกระทั่งกรดซิทริกเปลี่ยไปเป็นโมโน และ ได-โลหะแอลคาไลซิเทรท สารสองชนิดรวมกันประกอบด้วยสาร ผสมของดมโน และ ได-โลหะแอลคาไลซิเทรท ที่มีอัตราส่วนเชิง น้ำหนักระหว่าง 8/1 และ 1/10 ตามวิธีเฉพาะของการประดิษฐ์นี้สารผสมทางเภสัชกรรมจะประกอบ ด้วยต่อต้านกรดสำหรับการปฏิบัติอย่างต่อเนื่องของภาวะการมี กรดมากเกินไปในกระเทาะ และการหลั่งมากผิดปกติของฮีสทามีน สิทธิบัตรยา The foaming aggregates consist of a pharmaceutical ingredient and a method for the preparation of these two compounds. Made by the reaction between citric acid and alkali carbonate. or bicarbonate/mixture will react with prem and release. Carbon dioxide is released until citric acid is converted to mono and di-metal alkali citrate. The two substances are combined with a mixture of sniffing agent and di-metal alkali citrate. with a ratio weight between 8/1 and 1/10. According to the specific method of this invention, pharmaceutical mixtures are composed of with anti-acid for continuous practice of presence too much acid in the crackers and abnormal secretion of histamine, patent drug
Claims (4)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH4398A TH4398A (en) | 1987-09-01 |
| TH4001B true TH4001B (en) | 1994-09-23 |
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