TH39342A - Monoclonal antibodies against HIV-1 and vaccines made from it - Google Patents
Monoclonal antibodies against HIV-1 and vaccines made from itInfo
- Publication number
- TH39342A TH39342A TH9601001161A TH9601001161A TH39342A TH 39342 A TH39342 A TH 39342A TH 9601001161 A TH9601001161 A TH 9601001161A TH 9601001161 A TH9601001161 A TH 9601001161A TH 39342 A TH39342 A TH 39342A
- Authority
- TH
- Thailand
- Prior art keywords
- antibody
- hiv
- antibodies
- treatment
- monoclonal antibodies
- Prior art date
Links
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title claims 4
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 101000773038 Human herpesvirus 7 (strain RK) U21 glycoprotein Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract 2
- 241000699802 Cricetulus griseus Species 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 210000004102 animal cell Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000004754 hybrid cell Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้ได้เปิดเผยถึงแอนติบอดีที่สามารถใช้สำหรับสำหรับการผลิตวัคซีนเพื่อการแอคตีฟหรือพาส สีฟอิมมูไนซ์คนที่ ต้องการการรักษาดังกล่าว การประดิษฐ์นี้ยังได้ให้โมโนโคล นอลแอนติบอดีของคนที่ทำ หน้าที่เทียบเท่ากับแอนติบอดีที่กล่าว มาข้างต้นที่สร้างโดยเซลล์ไลน์ใด ๆ ของ CL1 ถึง CL6 (ฝากไว้ที่ European Collection of Animal Cell Cultures (ECACC) ที่ PHLS ใน Porton Down, Salisbury, UL) มันยังเป็นจุดมุ่งหมายของการประดิษฐ์ นี้เพื่อจะให้ไฮบริโดมาและหรือเซลล์ไลน์ CHO ที่สร้างแอนติบอดี ใด ๆ ที่เปิดเผยและอ้างสิทธิไว้ในที่นี้ การประดิษฐืนั้ยังได้มุ่งต่อของผสมของแอนติบอดีของการ ประดิษฐ์นี้ ตลอดจนวิธีใช้แอนติบอดีแต่ละ ตัวหรือของผสมของ มันสำหรับการตรวจหา การป้องกันและหรือการรักษาการติดเชื้อ HIV-1 ในภาวะทด สอบนอกกายและในกาย The invention discloses an antibody that can be used to produce active or passive vaccines. Immunize people who Need such treatment This invention also gave Mono Cole. Nal antibodies of people who do Function equivalent to the said antibody Came above created by any cell line of CL1 to CL6 (deposited at the European Collection of Animal Cell Cultures (ECACC) at PHLS in Porton Down, Salisbury, UL), it is also the aim of the invention. This is to allow the hybrid and / or CHO cell lines to generate any antibodies that are disclosed and claimed herein. Invention also focused on the antibody mixtures of this invention, as well as how each antibody was used. Body or mixture It's for detection Prevention and / or treatment of HIV-1 infection in the vitro and physical exam
Claims (3)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH39342A true TH39342A (en) | 2000-07-14 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5911989A (en) | HIV-vaccines | |
| DE3587512T2 (en) | Envelope antigens from the human immunodeficiency virus and their uses. | |
| US5922325A (en) | Synergistic neutralization of HIV-1 by human monoclonal antibodies and other antibodies directed against the v3 loop and the CD-4 binding site of GP-120,and the use for immunotherapy of HIV-1 infection | |
| Benjouad et al. | Influence of carbohydrate moieties on the immunogenicity of human immunodeficiency virus type 1 recombinant gp160 | |
| ATE122237T1 (en) | HIV-1 NEUTRALIZING MONOCLONAL ANTIBODIES. | |
| AT398080B (en) | IMMORTALIZED CELL LINE, METHOD FOR THEIR PRODUCTION AND METHOD FOR THE PRODUCTION OF MONOCLONAL ANTIBODIES, AND DIAGNOSTIC METHODS AND MEANS | |
| DE69126301D1 (en) | HIV-INDUCED SYNCYTIA BLOCKING ANTI-CD-4 ANTIBODIES | |
| EP0675904A4 (en) | HUMAN NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST HUMAN IMMUNODEFICIENCY VIRUS. | |
| DE69013950T2 (en) | Monoclonal antibody to differentiate HIV-2 seropositive from HIV-1 seropositive individuals. | |
| DE69133242T2 (en) | PEPTIDES FOR USE IN Vaccination And Stimulation Of Antibody Formation Against Human Immunodeficiency VIRUS | |
| US6132721A (en) | Non-Toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same | |
| DE69736474D1 (en) | ANTIBODIES AGAINST A COMPLEX OF CD4 AND A CHEMOKIN RECORD CORDOMA, AND THEIR USE AGAINST HIV INFECTIONS | |
| AU8010791A (en) | Hiv monoclonal antibody | |
| US6200575B1 (en) | Non-toxic immunogens derived from a retroviral regulatory protein antibodies preparation process and pharmaceutical compositions comprising them | |
| TH39342A (en) | Monoclonal antibodies against HIV-1 and vaccines made from it | |
| DK0516135T3 (en) | Human immunodeficiency virus-related immune preparation | |
| Kittelberger et al. | Evaluation of electrophoretic immunoblotting for the detection of antibodies against the bovine leukosis virus in cattle | |
| AP9901615A0 (en) | Multiple branch peptide constructions. | |
| Trujillo et al. | Shared antigenic epitopes on the V3 loop of HIV-1 gp120 and proteins on activated human T cells | |
| WO2002026253A1 (en) | A vaccine for acids and its preparation and use | |
| Chen et al. | HIV-1 gp41 shares a common immunologic determinant with human T, B and monocyte cell lines | |
| Morozov et al. | The Use of Thymic Peptides for Patients with Undetermined Human Immunodeficiency Virus | |
| Grundy et al. | Production of a Partially Acid Labile Alpha Interferon in Cytomegalovirus Pneumonitis | |
| Osther et al. | Protective humoral immune responses to the human immunodeficiency virus induced in immunized pigs: a possible source of therapeutic immunoglobulin preparations | |
| CA2046016A1 (en) | Hiv monoclonal antibody |