TH3218B - Components for inducing immunity against parasitic protozoa. - Google Patents
Components for inducing immunity against parasitic protozoa.Info
- Publication number
- TH3218B TH3218B TH8401000378A TH8401000378A TH3218B TH 3218 B TH3218 B TH 3218B TH 8401000378 A TH8401000378 A TH 8401000378A TH 8401000378 A TH8401000378 A TH 8401000378A TH 3218 B TH3218 B TH 3218B
- Authority
- TH
- Thailand
- Prior art keywords
- agar
- protozoa
- suspension
- previously
- substance
- Prior art date
Links
- 230000003071 parasitic effect Effects 0.000 title claims abstract 4
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 230000036039 immunity Effects 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 12
- 239000000725 suspension Substances 0.000 claims abstract 10
- 239000000126 substance Substances 0.000 claims abstract 9
- 238000004519 manufacturing process Methods 0.000 claims abstract 5
- 230000002163 immunogen Effects 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 3
- 244000045947 parasite Species 0.000 claims abstract 3
- 239000011159 matrix material Substances 0.000 claims abstract 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 3
- 229920001817 Agar Polymers 0.000 claims 3
- 235000010419 agar Nutrition 0.000 claims 3
- 229940072056 alginate Drugs 0.000 claims 3
- 235000010443 alginic acid Nutrition 0.000 claims 3
- 229920000615 alginic acid Polymers 0.000 claims 3
- 230000015271 coagulation Effects 0.000 claims 3
- 238000005345 coagulation Methods 0.000 claims 3
- 229910021645 metal ion Inorganic materials 0.000 claims 3
- 241000224483 Coccidia Species 0.000 claims 2
- 239000008272 agar Substances 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 235000013601 eggs Nutrition 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 244000144977 poultry Species 0.000 claims 2
- 241000206672 Gelidium Species 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 159000000007 calcium salts Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000012141 concentrate Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000012213 gelatinous substance Substances 0.000 abstract 1
Abstract
กระบวนการสำหรับเตรียมส่วนประกอบที่ทำให้เกิดภูมิคุ้มกันโรคโดยการกินเข้าไป (orally-administerable immunogenic composition) มีลักษณะพิเศษซึ่งประกอบด้วยโปรโตซัวที่เป็นพาราไซต์ที่มีเกราะหุ้มและยังมีชีวิตอยู่ (live encysted parasitic rotozoa) โดยฝังอยู่ภายในสารคล้ายวุ้นข้นที่แข็งตัวแล้ว (firmly-set gel matrix) ซึ่งโปรโตซัวสามารถออกมาได้หลังจากถูกกินเข้าไปโดยผู้ให้อาศัย (host)โดยกระบวนการดังกล่าวประกอบด้วยขั้นตอนการทำให้เกิดเป็นสารแขวนลอย (suspension) ของโปรโตซัวชนิดพาราไซต์ที่มีเกราะหุ้มและยังมีชีวิตอยู่ดังกล่าวในสารที่ทำให้เกิดเป็นสารคล้ายวุ้นข้น และทำให้สารแขวนลอยดังกล่าวแข็งตัวเป็นสารคล้ายวุ้นข้นที่แน่น สิทธิบัตรยา Process for preparing ingested immune-inducing components The orally-administerable immunogenic composition is characterized by live encysted parasitic rotozoa embedded within a firm-set agar-like substance. gel matrix) from which protozoa are released after being ingested by their host The process consists in the suspension of such live parasite protozoa in a gelatinous substance. and solidify the suspension into a dense gelatin-like substance.
Claims (4)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH2210A TH2210A (en) | 1985-02-01 |
| TH3218B true TH3218B (en) | 1993-03-26 |
Family
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