TH30770A - Pyrimido [1,2-a] New Indols - Google Patents
Pyrimido [1,2-a] New IndolsInfo
- Publication number
- TH30770A TH30770A TH9701001185A TH9701001185A TH30770A TH 30770 A TH30770 A TH 30770A TH 9701001185 A TH9701001185 A TH 9701001185A TH 9701001185 A TH9701001185 A TH 9701001185A TH 30770 A TH30770 A TH 30770A
- Authority
- TH
- Thailand
- Prior art keywords
- pyrimido
- indole
- straight
- carbon atoms
- replaced
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title claims abstract 5
- 239000003814 drug Substances 0.000 claims abstract 6
- 229940079593 drug Drugs 0.000 claims abstract 5
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 claims abstract 2
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000001367 artery Anatomy 0.000 abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 2
- HBBKFNCURJQICW-UHFFFAOYSA-N pyrimido[1,2-a]indole Chemical compound C1=CC=NC2=CC3=CC=CC=C3N21 HBBKFNCURJQICW-UHFFFAOYSA-N 0.000 abstract 2
- IJXJGQCXFSSHNL-UHFFFAOYSA-N 2-amino-2-phenylethanol Chemical group OCC(N)C1=CC=CC=C1 IJXJGQCXFSSHNL-UHFFFAOYSA-N 0.000 abstract 1
- -1 Phenyl glycineol pyrimido [1,2-a] indole Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
Abstract
DC60 (22/04/40) ไพริมิโด [1, 2-a] อินโดล ตามการประดิษฐ์ จะเตรียมได้จากการทำปฏิกิริยา ของอนุพันธ์กรดฟีนิล อะซีติก ที่ถูกแทนที่กับฟีนิลไกลซีนอล ไพริมิโด [1, 2-a] อินโดล อาจใช้ เป็นสารประกอบออกฤทธิ์ในยารักษาโรค โดยเฉพาะยารักษาที่มีฤทธิ์ต่อต้านผนังเส้นเลือดแดง ตีบตัน ไพริมิโด [1,2-a] อินโดล ตามการประดิษฐ์ จะเตรียมได้จากการทำปฏิกิริยาของอนุพันธ์กรดฟีนิล อะซีติก ที่ถูกแทนที่กับ ฟีนิลไกลซีนอล ไพริมิโด [1,2-a] อินโดล อาจใช้เป็นสารประ กอบออกฤทธิ์ในยารักษาโรค โดยเฉพาะยารักษาที่มีฤทธิ์ต่อต้าน ผนังเส้นเลือดแดงตีบตัน สิทธิบัตรยา DC60 (22/04/40) pyrimido [1, 2-a] indole based invention. Can be prepared from the reaction Of phenylacetic acid derivatives replaced with phenylglycineol pyrimidos [1, 2-a], indole may be used as an active ingredient in pharmaceuticals. In particular, drugs that are effective against the artery wall narrowing, pyrimido [1,2-a] indole, according to the invention It was obtained from the reaction of a phenylacetic acid derivative that was replaced with Phenyl glycineol pyrimido [1,2-a] indole may be used as a compound. Benefit from drug treatment Especially drugs that have antitumor effect Constricted artery wall, drug patent
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH30770A true TH30770A (en) | 1998-11-10 |
Family
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