TH173442A - Quinolicinone derivatives are PI3K inhibitors. - Google Patents
Quinolicinone derivatives are PI3K inhibitors.Info
- Publication number
- TH173442A TH173442A TH1601007888A TH1601007888A TH173442A TH 173442 A TH173442 A TH 173442A TH 1601007888 A TH1601007888 A TH 1601007888A TH 1601007888 A TH1601007888 A TH 1601007888A TH 173442 A TH173442 A TH 173442A
- Authority
- TH
- Thailand
- Prior art keywords
- compound
- prevention
- treatment
- quinolicinone
- derivatives
- Prior art date
Links
- 102000010400 1-phosphatidylinositol-3-kinase activity proteins Human genes 0.000 title claims abstract 3
- 108040005185 1-phosphatidylinositol-3-kinase activity proteins Proteins 0.000 title claims abstract 3
- 230000002401 inhibitory effect Effects 0.000 title claims abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 6
- 201000010099 disease Diseases 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 4
- 229940079593 drugs Drugs 0.000 claims abstract 4
- 230000002265 prevention Effects 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 239000011780 sodium chloride Substances 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 4
- 210000002435 Tendons Anatomy 0.000 claims abstract 2
- 201000011510 cancer Diseases 0.000 claims abstract 2
Abstract
การเปิดเผยคือสารประกอบสูตร (I), รูปแบบทัวโทเมอริค, สเทอรีโอไอโซเมอร์, เเละเกลือที่เ้ป็นที่ ยอมรับทางเภสัชกรรมของสารประกอบดังกล่าว, (สูตรเคมี) (I) ที่ซึ่ง R1-R4, เเละ n ตามที่กำหนดในข้อกำหนด, องค์ประกอบของยา ที่รวมถึง สารประกอบ, ทัวโทเมอร์ (tautomer), สเทอรีโอไอโซเมอร์, หรือเกลือของสารดังกล่าว, เเละวิธีของการรักษาหรือการป้องกันโรคหรือ ความผิดปกติ, ยกตัวอย่างเช่น, โรคมะเร็ง, ที่ตอบสนองต่อการรักษาหรือการป้องกันโดยการยับยั้งเอ็นไซม์ PI3K ของผู้รับการทดลอง สิทธิบัตรยา The disclosure is the compound formula (I), thetomeric form, stereoisomer, and the activated salt. Pharmacy of such compound, (chemical formula) (I) where R1-R4, and n as defined in the specification, drug composition including compound, tautomer, stere Rio isomers, or salts of such substances, and methods of treatment or prevention of diseases or disorders, for example, cancer, in response to treatment or prevention by inhibiting tendons. PI3K Sime of Drug Patent Trial
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH173442B TH173442B (en) | 2018-02-22 |
| TH173442A true TH173442A (en) | 2018-02-22 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201890338A1 (en) | OXADIAZOLIC DERIVATIVES SUITABLE AS HDAC INHIBITORS | |
| BR112015022340A2 (en) | method for treating or preventing a kallikrein-related disease or disorder in a subject, compound, and pharmaceutical composition | |
| EA201991580A1 (en) | PYRIMIDINE COMPOUND AND ITS PHARMACEUTICAL USE | |
| EA201790745A1 (en) | TRICYCLIC COMPOUNDS | |
| WO2016004404A3 (en) | Gls1 inhibitors for treating disease | |
| EA202091020A1 (en) | SUBSTITUTED IMIDAZOPYRIDINAMIDES AND THEIR APPLICATION | |
| BR112016025396A2 (en) | heterocyclyl butanamide derivatives | |
| WO2015033228A3 (en) | Compounds and use for treating cancer | |
| WO2016004413A3 (en) | Gls1 inhibitors for treating disease | |
| EA201692557A1 (en) | CINOLYSINUM DERIVATIVES AS PI3K INHIBITORS | |
| WO2015155680A3 (en) | Pyrazole derivatives as dihydroorotate dehydrogenase (dhodh) inhibitors | |
| TH173442A (en) | Quinolicinone derivatives are PI3K inhibitors. | |
| TH173442B (en) | Quinolicinone derivatives are PI3K inhibitors. | |
| WO2019040104A3 (en) | Compounds, salts thereof and their use for the treatment of diseases | |
| TH1701007409A (en) | Benzoxepin oxasolidinone compounds and methods of use | |
| TH1701002063A (en) | Aldosteron Synthes inhibitors | |
| TH1601002190A (en) | Pyrimidine substituted compounds And the use of substances as an inhibitor of splin tyrosine kinase (SYK) | |
| TH1801007671A (en) | Pyrazobopyrimidin derivatives as inhibitors of kinase reactions. | |
| TH1701001398A (en) | 1-alkyl-6-oxo-1,6-dihydropyridin-3-il compounds And using it as a SGRM controller | |
| TH174458A (en) | Pharmaceutical solids containing biotherin derivatives And the use of such elements | |
| TH163457A (en) | ||
| TH1801004949A (en) | new condensed pirimidine compounds or their salts | |
| TH176363A (en) | Sulfonamides that are modified substances of sodium channel. | |
| TH1601002685A (en) | Solid form of {[5- (3- chlorophenyl) -3-hydroxypyridine-2-carbonyl] amino} acetic acid, composition and use of that substance. | |
| TH146649A (en) | Histone inhibition |