TH160962A - "Multivalent elements Nimococcus polysaccharides - conjugated proteins " - Google Patents
"Multivalent elements Nimococcus polysaccharides - conjugated proteins "Info
- Publication number
- TH160962A TH160962A TH1501003240A TH1501003240A TH160962A TH 160962 A TH160962 A TH 160962A TH 1501003240 A TH1501003240 A TH 1501003240A TH 1501003240 A TH1501003240 A TH 1501003240A TH 160962 A TH160962 A TH 160962A
- Authority
- TH
- Thailand
- Prior art keywords
- polysaccharides
- proteins
- serotypes
- conjugated
- streptococcus pneumoniae
- Prior art date
Links
- 150000004676 glycans Polymers 0.000 title claims abstract 7
- 229920001282 polysaccharide Polymers 0.000 title claims abstract 7
- 239000005017 polysaccharide Substances 0.000 title claims abstract 7
- 150000004804 polysaccharides Polymers 0.000 title claims abstract 7
- 102000004169 proteins and genes Human genes 0.000 title claims abstract 5
- 108090000623 proteins and genes Proteins 0.000 title claims abstract 5
- 230000002163 immunogen Effects 0.000 claims abstract 4
- 241000193998 Streptococcus pneumoniae Species 0.000 claims abstract 3
- 229940031000 Streptococcus pneumoniae Drugs 0.000 claims abstract 3
- 239000000470 constituent Substances 0.000 claims abstract 3
- 102000014914 Carrier Proteins Human genes 0.000 claims abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 claims abstract 2
- 239000002671 adjuvant Substances 0.000 claims abstract 2
- 230000000240 adjuvant Effects 0.000 claims abstract 2
- 229910052782 aluminium Inorganic materials 0.000 claims abstract 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminum Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract 2
- 201000010099 disease Diseases 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 229960005486 vaccines Drugs 0.000 claims abstract 2
- 239000000969 carrier Substances 0.000 claims 1
- 230000002998 immunogenetic Effects 0.000 claims 1
Abstract
คำขอใหม่ปรับปรุงวันที่ 18/04/2559 การประดิษฐ์นี้จัดให้มีองค์ประกอบอิมมูโนจีนิกที่ประกอบรวมด้วย 13 โพลีแซคคาไรด์-โปรตีน คอนจูเกตที่ต่างกัน แต่ละคอนจูเกตประกอบรวมด้วยแคปซูลาโพลีแซคคาไรด์ที่ถูกเตรียมจากซีไรไทป์ต่างๆ ของStreptococcus pneumoniae ถูกคอนจูเกตกับโปรตีนตัวพา กล่าวคือ 12 ซีโรไทป์ ที่ถูกเลือกจากกลมที่ ประกอบด้วย 1,3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, และ 23F และซีโรไทป์ 22F หรือ 33F องค์ประกอบอิมมูโนจีนิกที่ถูกผสมเป็นวัคซีนที่ประกอบรวมด้วยแอดจูแวนท์ที่มีส่วนผสมของอัลลูมิเนียมเพิ่ม ความครอบคลุมที่เกี่ยวข้องกับโรคนิวโมคอกคัสในทารกและเด็ก สิทธิบัตรยา New Request Revised 04/18/2016 This invention provides an immunogenic component comprising 13 polysaccharides - proteins. Different conjugates Each conjugate consists of a capula polysaccharide prepared from various zerotypes. Streptococcus pneumoniae was conjugated with carrier proteins, ie, 12 serotypes selected from spheres containing 1,3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, And 23F and 22F or 33F serotypes. The immunogenic constituents were mixed in a vaccine containing an adjuvant containing aluminum added. Coverage related to pneumococcal disease in infants and children, drug patents.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH160962B TH160962B (en) | 2017-03-23 |
| TH160962A true TH160962A (en) | 2017-03-23 |
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