TH156282A - The modified Marex disease virus and the vaccines made from it - Google Patents
The modified Marex disease virus and the vaccines made from itInfo
- Publication number
- TH156282A TH156282A TH1401005529A TH1401005529A TH156282A TH 156282 A TH156282 A TH 156282A TH 1401005529 A TH1401005529 A TH 1401005529A TH 1401005529 A TH1401005529 A TH 1401005529A TH 156282 A TH156282 A TH 156282A
- Authority
- TH
- Thailand
- Prior art keywords
- marex
- virus
- mdv
- chickens
- vaccine
- Prior art date
Links
- OCJYIGYOJCODJL-UHFFFAOYSA-N Meclizine Chemical class CC1=CC=CC(CN2CCN(CC2)C(C=2C=CC=CC=2)C=2C=CC(Cl)=CC=2)=C1 OCJYIGYOJCODJL-UHFFFAOYSA-N 0.000 title claims abstract 5
- 241000700605 Viruses Species 0.000 title claims abstract 5
- 229960005486 vaccines Drugs 0.000 title claims abstract 5
- 201000010099 disease Diseases 0.000 title claims abstract 3
- 241000287828 Gallus gallus Species 0.000 claims abstract 4
- 239000003795 chemical substances by application Substances 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 4
- 229940079593 drugs Drugs 0.000 claims abstract 4
- 229920001272 Exogenous DNA Polymers 0.000 claims abstract 2
- 241000712909 Reticuloendotheliosis virus Species 0.000 claims abstract 2
- 239000000969 carrier Substances 0.000 claims abstract 2
- 239000003085 diluting agent Substances 0.000 claims abstract 2
- 238000009472 formulation Methods 0.000 claims abstract 2
- 230000028993 immune response Effects 0.000 claims abstract 2
- 230000001506 immunosuppresive Effects 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 2
- 230000000638 stimulation Effects 0.000 claims abstract 2
- 230000003612 virological Effects 0.000 claims abstract 2
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000001131 transforming Effects 0.000 abstract 1
Abstract
DC60 (25/11/57) การประดิษฐ์นี้ให้วัคซีนที่มีประสิทธิภาพสำหรับโรคมาเร็กซ์ซึ่งอาจถูกเตรียมโดยใช้ไวรัส โรคมาเร็กซ์ (MDV) ชนิดรีคอมบิแนนต์สายพันธุ์ CVI988 ที่ได้ถูกทรานสฟอร์มด้วยคอนสตรัคต์ DNA จากภายนอกซึ่งรวมถึงลำดับส่วนซ้ำยาวด้านปลายของไวรัสเรติคิวโลเอนโดธีลิโอซิส เอเจนต์ไวรัสที่ปลอดภัยนี้กระตุ้นการตอบสนองทางภูมิคุ้มกันแบบป้องกันอย่างสูงในไก่ต่อ การกระตุ้นทดสอบด้วย MDV ชนิดรุงแรงโดยไม่ก่อให้เกิดระดับที่มีนัยสำคัญของความสามารถ ก่อโรค สูตรผสมที่เหมาะสมของวัคซีนสำหรับการใช้ในไก่รวมถึงขนาดยาการสร้างภูมิคุ้มกันที่มี ประสิทธิภาพของเอเจนต์ไวรัสใหม่นี้พร้อมด้วยตัวพาหรือสารช่วยเจือจางที่เป็นที่ยอมรับทาง ภูมิคุ้มกัน สิทธิบัตรยา DC60 (25/11/14) This invention provides an effective vaccine for Marex disease that may have been prepared using the recombinant marex virus (MDV) strain CVI988. Transformation by exogenous DNA constructor, including the distal long iterative sequence of the reticuloendotheliosis virus. This safe virus agent activates a highly defensive immune response in chickens against Stimulation tested with strong MDV without producing a significant degree of pathogenicity, the appropriate formulation of the vaccine for use in chickens, including the available immunization drug size. The efficacy of this new viral agent, along with an immunosuppressive carrier or diluent, patent drug
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH156282A true TH156282A (en) | 2016-09-16 |
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