TH137482A - Microbial production of high-value chemical products and related components, methods and systems - Google Patents
Microbial production of high-value chemical products and related components, methods and systemsInfo
- Publication number
- TH137482A TH137482A TH1201003835A TH1201003835A TH137482A TH 137482 A TH137482 A TH 137482A TH 1201003835 A TH1201003835 A TH 1201003835A TH 1201003835 A TH1201003835 A TH 1201003835A TH 137482 A TH137482 A TH 137482A
- Authority
- TH
- Thailand
- Prior art keywords
- chemical products
- methods
- systems
- related components
- microbial production
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 5
- 238000004519 manufacturing process Methods 0.000 title claims abstract 4
- 238000000034 method Methods 0.000 title claims 3
- 230000000813 microbial effect Effects 0.000 title claims 2
- 244000005700 microbiome Species 0.000 claims abstract 3
- 238000004113 cell culture Methods 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000015303 Fatty Acid Synthases Human genes 0.000 claims 1
- 108010039731 Fatty Acid Synthases Proteins 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 abstract 4
- 241000894006 Bacteria Species 0.000 abstract 2
- LTYOQGRJFJAKNA-KKIMTKSISA-N Malonyl CoA Natural products S(C(=O)CC(=O)O)CCNC(=O)CCNC(=O)[C@@H](O)C(CO[P@](=O)(O[P@](=O)(OC[C@H]1[C@@H](OP(=O)(O)O)[C@@H](O)[C@@H](n2c3ncnc(N)c3nc2)O1)O)O)(C)C LTYOQGRJFJAKNA-KKIMTKSISA-N 0.000 abstract 2
- 238000010353 genetic engineering Methods 0.000 abstract 2
- LTYOQGRJFJAKNA-DVVLENMVSA-N malonyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 LTYOQGRJFJAKNA-DVVLENMVSA-N 0.000 abstract 2
- 230000002503 metabolic effect Effects 0.000 abstract 2
- 229930001119 polyketide Natural products 0.000 abstract 2
- 125000000830 polyketide group Chemical group 0.000 abstract 2
Abstract
DC60(12/12/55) การประดิษฐ์นี้เกี่ยวข้องกับเชื้อจุลชีพที่ถูกผ่านกระบวนการพันธุวิศวกรรมแบบเมตาโบลิก ได้แก่เชื้อแบคทีเรียซึ่งมีการใช้ที่เพิ่มขึ้นของมาโลนิลCoAสำหรับการผลิตผลิตภัณฑ์ทางเคมีซึ่ง รวมถึงโพลีคีไทด์และ3ไฮดรอกซีโพรพิโอนิกแอซิด การประดิษฐ์นี้เกี่ยวข้องกับเชื้อจุลชีพที่ถูกผ่านกระบวนการพันธุวิศวกรรมแบบเมตาโบลิก ได้แก่เชื้อแบคทีเรียซึ่งมีการใช้ที่เพิ่มขึ้นของมาโลนิลCoAสำหรับการผลิตผลิตภัณฑ์ทางเคมีซึ่ง รวมถึงโพลีคีไทด์และ3ไฮดรอกซีโพรพิโอนิกแอซิด DC60(12/12/55) This invention relates to microorganisms that have been subjected to metabolic genetic engineering. including bacteria which have increased use of malonyl CoA for the production of chemical products which Includes polyketides and 3-hydroxypropionic acid. The present invention relates to microorganisms that have been subjected to metabolic genetic engineering. including bacteria which have increased use of malonyl CoA for the production of chemical products which Includes polyketides and 3-hydroxypropionic acid.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH137482A true TH137482A (en) | 2014-10-17 |
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