TH135147B - Secandary derivatives 8-Hydroxycquinoline-7-New type of carboxamide - Google Patents
Secandary derivatives 8-Hydroxycquinoline-7-New type of carboxamideInfo
- Publication number
- TH135147B TH135147B TH1201003222A TH1201003222A TH135147B TH 135147 B TH135147 B TH 135147B TH 1201003222 A TH1201003222 A TH 1201003222A TH 1201003222 A TH1201003222 A TH 1201003222A TH 135147 B TH135147 B TH 135147B
- Authority
- TH
- Thailand
- Prior art keywords
- hydroxycquinoline
- compounds
- new type
- carboxamide
- derivatives
- Prior art date
Links
- 125000003917 carbamoyl group Chemical class [H]N([H])C(*)=O 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 3
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 239000011780 sodium chloride Substances 0.000 claims abstract 2
- 241000228245 Aspergillus niger Species 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 229940095731 Candida albicans Drugs 0.000 abstract 1
- 241000222122 Candida albicans Species 0.000 abstract 1
- 241000825258 Scopulariopsis brevicaulis Species 0.000 abstract 1
- 241000222126 [Candida] glabrata Species 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Abstract
(สูตรเคมี) การประดิษฐ์นี้ให้อนุพันธ์เซคันดารี่ 8-ไฮดรอกซิควิโนลีน-7-คาร์บอกซาไมด์ ชนิดใหม่ตาม สูตรทั่วไป (I) และเกลือซึ่งเป็นที่ยอมรับทางเภสัชกรรมของสารนี้ สารประกอบเหล่านี้มีปรโยชน์ใน การเป็นสารต้านเชื้อรา โดยเฉพาเจาะจง คือ, สารประกอบเหล่านี้ถูกนำมาทดสอบต่อ Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger และ Scopulariopsis Brevicaulis สารประกอบเหล่านี้หลาย ๆ ชนิดมีฤทธิ์ต่อ Candida สปีชี่ส์ เช่น Candida Albicans และ Candida Glabrata (Chemistry formula) This invention gave the second derivative A new type of 8-hydroxycquinoline-7-carboxamide based on the general formula (I) and a chemically acceptable salt of this substance. These compounds have a beneficial effect on Being an antifungal agent Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis.Many of these compounds are active against Candida species such as Candida Albicans and Candida Glabrata.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH135147B true TH135147B (en) | 2014-07-08 |
| TH135147A TH135147A (en) | 2014-07-08 |
Family
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