TH127237B - Secandary derivatives 8-hydroxycquinoline-7-carboxamides for antifungal use - Google Patents
Secandary derivatives 8-hydroxycquinoline-7-carboxamides for antifungal useInfo
- Publication number
- TH127237B TH127237B TH1201003221A TH1201003221A TH127237B TH 127237 B TH127237 B TH 127237B TH 1201003221 A TH1201003221 A TH 1201003221A TH 1201003221 A TH1201003221 A TH 1201003221A TH 127237 B TH127237 B TH 127237B
- Authority
- TH
- Thailand
- Prior art keywords
- formula
- secandary
- compounds
- hydroxycquinoline
- carboxamides
- Prior art date
Links
- 230000000843 anti-fungal Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 3
- 239000003429 antifungal agent Substances 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 239000011780 sodium chloride Substances 0.000 claims abstract 2
- FOXMISVOVQTSGS-UHFFFAOYSA-N 8-hydroxyquinoline-7-carboxamide Chemical compound C1=CC=NC2=C(O)C(C(=O)N)=CC=C21 FOXMISVOVQTSGS-UHFFFAOYSA-N 0.000 abstract 1
- 241000228245 Aspergillus niger Species 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 229940095731 Candida albicans Drugs 0.000 abstract 1
- 241000222122 Candida albicans Species 0.000 abstract 1
- 241000825258 Scopulariopsis brevicaulis Species 0.000 abstract 1
- 241000222126 [Candida] glabrata Species 0.000 abstract 1
Abstract
(สูตรเคมี ) (I) การประดิษฐ์นี้ให้อนุพันธ์เซคันดารี่ 8- ไฮดรอกซีควิดนลีน -7- คาร์บอกซาไมด์ตามสูตรทั่วไป (I) และ เกลือซึ่งเป็นที่ยอมรับทางเภสัชกรรมของสารนี้ สารประกอบเหล่านี้มีประโยชน์ในการเป็นสารต้าน เชื้อรา โดยเฉพาะเจาะจงคือ สารประกอบเหล่านี้ถูกนำมาทดสอบต่อ Tricophyton Rubrum, Tricophyton Mentagrophytes,Aspergillus Niger และ Scopulariopsis Brevicaulis สารประกอบ เหล่านี้มีฤทธิ์ต่อ Candida สปีชี่ส์ เช่น Candida Albicans และ Candida Glabrata (Chemical formula) (I) This invention provides the derivative of secandary 8-hydroxyquinoline-7-carboxamide according to the general formula (I) and a well-established pharmaceutical salt of This substance These compounds are particularly useful as antifungal agents: These compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis.These compounds were active against Candida species such as Candida Albicans and Candida Glabrata.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH127237B true TH127237B (en) | 2013-09-20 |
| TH127237A TH127237A (en) | 2013-09-20 |
Family
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