TH133355B - Derivatives 3- (heteroaryyl-amino) -1,2,3,4-tetrahydro-9H-carbazole (3- (heteroaryl-amino) -1,2,3,4-tetrahydro-9H-carbazole derivative) and their use as prostaglandin receptor modulators (prostaglandin receptor modulators) - Google Patents
Derivatives 3- (heteroaryyl-amino) -1,2,3,4-tetrahydro-9H-carbazole (3- (heteroaryl-amino) -1,2,3,4-tetrahydro-9H-carbazole derivative) and their use as prostaglandin receptor modulators (prostaglandin receptor modulators)Info
- Publication number
- TH133355B TH133355B TH1201004835A TH1201004835A TH133355B TH 133355 B TH133355 B TH 133355B TH 1201004835 A TH1201004835 A TH 1201004835A TH 1201004835 A TH1201004835 A TH 1201004835A TH 133355 B TH133355 B TH 133355B
- Authority
- TH
- Thailand
- Prior art keywords
- amino
- tetrahydro
- receptor modulators
- carbazole
- prostaglandin receptor
- Prior art date
Links
- 230000000051 modifying Effects 0.000 title abstract 4
- 102000015433 Prostaglandin Receptors Human genes 0.000 title abstract 3
- 108010050183 Prostaglandin Receptors Proteins 0.000 title abstract 3
- 125000005241 heteroarylamino group Chemical group 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 2
- 125000006536 (C1-C2)alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000003709 fluoroalkyl group Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract 2
- 102000009389 Prostaglandin D receptors Human genes 0.000 abstract 1
- 108050000258 Prostaglandin D receptors Proteins 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000000599 controlled substance Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Abstract
การประดิษฐ์ครั้งนี้เกี่ยวข้องกับอนุพันธ์ 3-(เฮทเทอโรแอริล-อะมิโน)-1,2,3,4-เตตระ ไฮโดร-9H-คาร์บาโซล (3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivative) ตามสูตร (I), (สูตรเคมี) (I) โดยที่ R1, R2 และ R3 คือดังที่อธิบายไว้ในรายละเอียด และการใช้งานของพวกมันเป็นสารปรับควบคุม พรอสตาแกลนดินรีเซพเตอร์ (prostaglandin receptor modulators), โดยเฉพาะเจาะจงมากสุด คือ โดยเป็น สารปรับควบคุมพรอสตาแกลนดิน D2 รีเซพเตอร์, ในการบำบัดโรคและความผิดปกติต่างๆ ที่สื่อโดยพรอสตาแกลนดิน, เกี่ยวข้องกับองค์ประกอบเชิงเภสัชกรรมซึ่งมีสารประกอบเหล่านี้ และ เกี่ยวข้องกับกระบวนการสำหรับการจัดเตรียมพวกมัน This invention involved a derivative. 3- (heteroeryl-amino) -1,2,3,4-tetra Hydro-9H-Carbazole (3- (heteroaryl-amino) -1,2,3,4-tetrahydro-9H-carbazole derivative) according to the formula (I), (chemical formula) (I) where R1, R2 and R3 are as described in each Fine And their use as a controlled substance Prosta Glandin Receptor Prostaglandin D2 receptor modulators, most specifically, are prostaglandin receptor modulators, in the treatment of diseases and disorders. Informed by prostaglandin, it is related to the pharmaceutical constituents which contain these compounds and is involved in the process for preparing them.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH133355B true TH133355B (en) | 2014-05-06 |
| TH133355A TH133355A (en) | 2014-05-06 |
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