TH13324B - New type of slime-adherent emulsion - Google Patents
New type of slime-adherent emulsionInfo
- Publication number
- TH13324B TH13324B TH9501001072A TH9501001072A TH13324B TH 13324 B TH13324 B TH 13324B TH 9501001072 A TH9501001072 A TH 9501001072A TH 9501001072 A TH9501001072 A TH 9501001072A TH 13324 B TH13324 B TH 13324B
- Authority
- TH
- Thailand
- Prior art keywords
- mixture
- cyclodextrin
- weight
- derivatives
- emulsion
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 13
- 229920000858 Cyclodextrin Polymers 0.000 claims abstract 7
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims abstract 7
- 229940079593 drug Drugs 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims 4
- 229960004130 itraconazole Drugs 0.000 claims 4
- 239000003381 stabilizer Substances 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000003232 mucoadhesive effect Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 239000007762 w/o emulsion Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 210000003097 mucus Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวกับการใช้ไซโคลเคกส์ทรินหรืออนุพันธ์ของสารนั้นในการเป็นสาร ยึดติดกับเมือกในอิมัลชันหรือสารละลายแอเควียส, ใช้ไซโคลเดกซ์ทรินหรืออนุพันธ์ของสารนั้นดังกล่าว ในปริมาณจาก 10% ถึง 70% โดยน้ำหนักบนพื้นฐานของน้ำหนักทั้งหมดของสารผสม สิทธิบัตรยา The invention is concerned with the use of cyclokextrin or its derivatives as a substance. Adheres to mucus in an emulsion or aqueous solution, uses cyclodextrin or its derivatives in amounts from 10% to 70% by weight on the basis of the total weight of the drug patent mixture.
Claims (9)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH19571A TH19571A (en) | 1996-07-16 |
| TH13324B true TH13324B (en) | 2002-08-09 |
Family
ID=
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