TH126216B - Salt pill formulas of 8 - ((1- (3,5-bis - (trifluoromethyl) phenyl) - ethoxi) - methyl] -8-phenyl-1,7-diea S-Spiro [4,5] Decan-2-transfer and the pills made from it. - Google Patents
Salt pill formulas of 8 - ((1- (3,5-bis - (trifluoromethyl) phenyl) - ethoxi) - methyl] -8-phenyl-1,7-diea S-Spiro [4,5] Decan-2-transfer and the pills made from it.Info
- Publication number
- TH126216B TH126216B TH801001384A TH0801001384A TH126216B TH 126216 B TH126216 B TH 126216B TH 801001384 A TH801001384 A TH 801001384A TH 0801001384 A TH0801001384 A TH 0801001384A TH 126216 B TH126216 B TH 126216B
- Authority
- TH
- Thailand
- Prior art keywords
- phenyl
- ethoxi
- decan
- trifluoromethyl
- bis
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title claims 2
- 239000011780 sodium chloride Substances 0.000 title claims 2
- 239000006187 pill Substances 0.000 title abstract 3
- -1 3,5-bis - (trifluoromethyl) phenyl Chemical group 0.000 title abstract 2
- 229940023488 Pill Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- WSVLPVUVIUVCRA-RJMJUYIDSA-N (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-RJMJUYIDSA-N 0.000 claims 1
- FYGDTMLNYKFZSV-MRCIVHHJSA-N Dextrin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1O[C@@H]1[C@@H](CO)OC(O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-MRCIVHHJSA-N 0.000 claims 1
- 229960001021 Lactose Monohydrate Drugs 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 235000010980 cellulose Nutrition 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000007906 compression Methods 0.000 claims 1
- 239000002270 dispersing agent Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract 1
Abstract
สูตรทางเภสัชกรรมที่มีเหลือของ (5S,8S)-8-[{(1R)-1-(3,5-บิส-(ไตรฟลูออโรเมธีล)ฟีนิล) -อีธอกซี}-เมธิล]-8-ฟีนิล-1,7-ไดเอซาสไปโร[4.5]เดแคน-2-โอน, ที่แสดงเป็นตัวอย่างโดยสูตร I, ซึ่ง เหมาะสมสำหรับการสร้างไปเป้นรูปแบบยาเม็ด, เช้นเดียวกับรูปแบบยาเม็ดถูกเปิดเผย ที่เปิดเผย เป้นวิธีการของการใช้ประโยชน์รูปแบบยาเช่นนี้ในการรักษาได้ด้วยเหมือนกัน Pharmaceutical formulas with the rest of (5S, 8S) -8 - (((1R) -1- (3,5-bis - (trifluoromethyl) phenyl) - ethoxi) - methyl) -8- Phenyl-1,7-diasspiro [4.5] decan-2-transfer, as illustrated by Formula I, is suitable for making a pill, as well as a formulation. The tablets were disclosed as a means of utilizing this form of medicine in treating as well.
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH126216A TH126216A (en) | 2013-08-19 |
TH126216B true TH126216B (en) | 2013-08-19 |
Family
ID=
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