TH124818B - Nucleocides and their analogous nucleotides replaced. - Google Patents
Nucleocides and their analogous nucleotides replaced.Info
- Publication number
- TH124818B TH124818B TH1101002103A TH1101002103A TH124818B TH 124818 B TH124818 B TH 124818B TH 1101002103 A TH1101002103 A TH 1101002103A TH 1101002103 A TH1101002103 A TH 1101002103A TH 124818 B TH124818 B TH 124818B
- Authority
- TH
- Thailand
- Prior art keywords
- nucleocides
- nucleotides
- nucleotides replaced
- analogous
- sulfur
- Prior art date
Links
- 125000003729 nucleotide group Chemical group 0.000 title abstract 5
- 239000002773 nucleotide Substances 0.000 title abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 239000011593 sulfur Substances 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atoms Chemical class [H]* 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrugs Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 235000021317 phosphate Nutrition 0.000 abstract 3
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 2
- 208000006551 Parasitic Disease Diseases 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K [O-]P([O-])([O-])=O Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing Effects 0.000 abstract 1
- 230000003612 virological Effects 0.000 abstract 1
Abstract
ที่ถูกเปิดเผยในที่นี้คือนิวคลีโอไทด์แอนะล็อก(nucleotide analogs)ที่มีฟอสเฟต(phosphates)ที่ได้รับการป้องกัน,วิธีการของการสังเคราะห์นิวคลีโอไทด์แอนะล็อกที่มีฟอสเฟตที่ได้รับการป้องกัน,และวิธีการสำหรับการบำบัดโรคและ/หรือสภาวะดังเช่นการติดเชื้อไวรัส,มะเร็ง,และ/หรือโรคที่เกี่ยวกับปรสิตด้วยนิวคลีโอไทด์แอนะล็อกที่มีฟอสเฟตที่ได้รับการป้องกัน Revealed here are nucleotides, analogues (nucleotides). Analogs) containing protected phosphates, methods of synthesis of nucleotide analogs containing protected phosphates, and methods for the treatment of diseases and / or conditions such as Viral, cancer, and / or parasitic infection with phosphate-containing analog nucleotides
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH124818A TH124818A (en) | 2013-06-28 |
| TH124818B true TH124818B (en) | 2013-06-28 |
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