TH104259B - Spyrochetals with fused rings and their use As an antidiabetic drug - Google Patents
Spyrochetals with fused rings and their use As an antidiabetic drugInfo
- Publication number
- TH104259B TH104259B TH701003385A TH0701003385A TH104259B TH 104259 B TH104259 B TH 104259B TH 701003385 A TH701003385 A TH 701003385A TH 0701003385 A TH0701003385 A TH 0701003385A TH 104259 B TH104259 B TH 104259B
- Authority
- TH
- Thailand
- Prior art keywords
- chemical formula
- formula
- group
- spyrochetals
- compounds
- Prior art date
Links
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 8
- 150000001875 compounds Chemical class 0.000 claims abstract 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 claims abstract 2
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims abstract 2
- 125000003118 aryl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- 239000000470 constituent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000529 probiotic Effects 0.000 abstract 1
- 239000006041 probiotic Substances 0.000 abstract 1
- 235000018291 probiotics Nutrition 0.000 abstract 1
Abstract
ที่จัดเตรียมเป็นสารประกอบซึ่งแทนโดยสูตร (I) [สูตร 1] (สูตรเคมี (I) ที่ซึ่ง R1,R2,R3 , และ R4 อย่างไม่ขึ้นแก่กัน แต่ละหมู่ได้รับการคัดเลือกจากอะตอมของ ไฮโดรเจน, หมู่ C1-6 แอลคิลซึ่งอาจได้รับการแทนที่, หมู่ C7-14 อะแรลคิลซึ่งอาจได้รับการแทนที่ และ -C (=O) Rx; n บ่งชี้ จำนวนเต็มที่ได้รับการคัดเลือกจาก 1 และ 2; และวงแหวน Ar ไดัรับการคัดเลือก จากหมู่ที่แทนโดยสูตร (a) ถึง (f) ต่อไปนี้ : [สูตร 2] (สูตรเคมี) (a) (สูตรเคมี) (b) (สูตรเคมี) (c) (สูตรเคมี) (d) (สูตรเคมี) (e) (สูตรเคมี) (f) หรือโพรดรักของสารประกอบ หรือเกลือที่สามารถยอมรับได้ทางเภสัชกรรมของ สารประกอบ และรวมทั้งยารักษาโรคและองค์ประกอบทางเภสัชกรรมที่มีสารประกอบ หรือ โพรดรัก ของสารประกอบ หรือเกลือที่สามารถยอมรับได้ทางเภสัชกรรมของสารประกอบ ดังกล่าว: Provided as a compound represented by formula (I) [Formula 1] (chemical formula (I), where R1, R2, R3, and R4 are independent of each other. Each group is selected from the hydrogen atom, the C1-6 alkyl group which may be substituted, the C7-14 aralkyl group which may be substituted, and -C (= O) Rx; n indicates the integer selected from 1 and 2; And the Ar ring has been selected From the group represented by the following formulas (a) to (f): [Formula 2] (Chemical Formula) (a) (Chemical Formula) (b) (Chemical Formula) (c) (Chemical Formula) (d) (Chemical Formula) (e. ) (Chemical formula) (f) or compound prop love Or pharmaceutical acceptable salts of compounds and including therapeutic agents and pharmaceutical constituents containing compounds or probiotics of the compound or of the pharmaceutical salts of such compounds:
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH104259A TH104259A (en) | 2010-09-24 |
| TH104259B true TH104259B (en) | 2010-09-24 |
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