TH101968B - 2-aryl-6-phenyl-imidazo [1,2-a] derivative of Pyridine. Preparation of such substances and their use in the treatment of diseases. - Google Patents
2-aryl-6-phenyl-imidazo [1,2-a] derivative of Pyridine. Preparation of such substances and their use in the treatment of diseases.Info
- Publication number
- TH101968B TH101968B TH701004738A TH0701004738A TH101968B TH 101968 B TH101968 B TH 101968B TH 701004738 A TH701004738 A TH 701004738A TH 0701004738 A TH0701004738 A TH 0701004738A TH 101968 B TH101968 B TH 101968B
- Authority
- TH
- Thailand
- Prior art keywords
- group
- cycloalkyl
- replaced
- groups
- derivative
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 150000003222 pyridines Chemical class 0.000 title 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 3
- 125000001624 naphthyl group Chemical group 0.000 claims abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 2
- 125000004429 atoms Chemical group 0.000 claims 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000000875 corresponding Effects 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 abstract 4
- 150000008043 acidic salts Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
Abstract
การประดิษฐ์นั้นเกี่ยวข้องกับอนุพันธ์ ที่มีสูตรทั่วไป (I) (สูตรเคมี) (I) ซึ่ง R1 คือหมู่เฟนิลหรือหมู่แนฟธิล เป็นไปได้สำหรับ 2 หมู่ดังกล่าวที่จะเลือกให้ถูกแทนที่ R2 และ R3 ที่ไม่เกี่ยวข้องกันคือไฮโดรเจนอะตอมหรือหมู่ (C1-C6)แอลคิล, (C3-C7) ไซโคลแอลคิลหรือ (C3-C7) ไซโคลแอลคิล(C1-C3) แอลคิลีนซึ่งเลือกให้ถูกแทนที่ ; หมู่แอริลซึ่งเลือกให้ถูกแทนที่ R4 คือ: ไฮโดรเจนอะตอมหรือหมู่ (C1-C6)แอลคิล, (C3-C7) ไซโคลแอลคิลหรือ(C3-C7) ไซโคลแอลคิล (C1-C3) แอลคิลีนซึ่งเลือกให้ถูกแทนที่; หมู่แอริลซึ่งเลือกให้ถูกแทนที่ด้วยหมู่แทนที่ 1หมู่หรือมากกว่า ในรูปของ เบสหรือเกลือแบบรวมตัวกับกรด กรรมวิธีสำหรับการเตรียม และการใช้ในการรักษาโรค: The invention is related to the derivative. With the general formula (I) (chemical formula) (I), where R1 is a phenyl group or a naphthyl group. It is possible for these 2 groups to be substituted for the unrelated R2 and R3, hydrogen atom or group. (C1-C6) alkyl, (C3-C7) cycloalkyl or (C3-C7) cycloalkyl, (C1-C3) alkyline which was selected to be replaced; The aryl group that is chosen to be replaced R4 is: hydrogen atom or group. (C1-C6) alkyl, (C3-C7) cycloalkyl or (C3-C7) cycloalkyl, (C1-C3) alkyline which was selected to be replaced; Ariel groups that are chosen to be replaced with replacement groups 1 group or more as bases or acidic salts Methods for preparation And its use in the treatment of disease:
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH101968B true TH101968B (en) | 2010-06-25 |
TH101968A TH101968A (en) | 2010-06-25 |
Family
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