SV2018005657A - "nuevos derivados de imidazo[4,5-b]piridina, un proceso para su preparacion y composiciones farmaceuticas que los contienen" - Google Patents

"nuevos derivados de imidazo[4,5-b]piridina, un proceso para su preparacion y composiciones farmaceuticas que los contienen"

Info

Publication number
SV2018005657A
SV2018005657A SV2018005657A SV2018005657A SV2018005657A SV 2018005657 A SV2018005657 A SV 2018005657A SV 2018005657 A SV2018005657 A SV 2018005657A SV 2018005657 A SV2018005657 A SV 2018005657A SV 2018005657 A SV2018005657 A SV 2018005657A
Authority
SV
El Salvador
Prior art keywords
piridina
imidazo
contain
preparation
pharmaceutical compositions
Prior art date
Application number
SV2018005657A
Other languages
English (en)
Inventor
András Kotschy
Nicolas Foloppe
David Wamsley
Michaël Frank Burbridge
Francisco Humberto Cruzalegui
Balázs Balint
Melinda Sipos
Csaba Wéber
Original Assignee
Servier Lab
Vernalis R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab, Vernalis R&D Ltd filed Critical Servier Lab
Publication of SV2018005657A publication Critical patent/SV2018005657A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

COMPUESTOS DE FÓRMULA (I): (VER FORMULA) EN LA QUE R1, R2, R3, R4, Y R5 SON COMO SE DEFINEN EN LA DESCRIPCIÓN
SV2018005657A 2015-09-30 2018-03-22 "nuevos derivados de imidazo[4,5-b]piridina, un proceso para su preparacion y composiciones farmaceuticas que los contienen" SV2018005657A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1559252A FR3041639B1 (fr) 2015-09-30 2015-09-30 NOUVEAUX DERIVES D'IMIDAZO[4,5-b]PYRIDINE, PROCEDE POUR LES PREPARER ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

Publications (1)

Publication Number Publication Date
SV2018005657A true SV2018005657A (es) 2018-07-31

Family

ID=54979755

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2018005657A SV2018005657A (es) 2015-09-30 2018-03-22 "nuevos derivados de imidazo[4,5-b]piridina, un proceso para su preparacion y composiciones farmaceuticas que los contienen"

Country Status (26)

Country Link
US (1) US20180273528A1 (es)
EP (1) EP3356363A1 (es)
JP (1) JP2018535931A (es)
KR (1) KR20180054858A (es)
CN (1) CN108137581A (es)
AU (1) AU2016333505A1 (es)
BR (1) BR112018006157A2 (es)
CA (1) CA2999935A1 (es)
CL (1) CL2018000783A1 (es)
CO (1) CO2018003473A2 (es)
CR (1) CR20180181A (es)
CU (1) CU20180028A7 (es)
DO (1) DOP2018000083A (es)
EA (1) EA201890821A1 (es)
EC (1) ECSP18023253A (es)
FR (1) FR3041639B1 (es)
HK (1) HK1255804A1 (es)
IL (1) IL258341A (es)
MA (1) MA43020A (es)
MX (1) MX2018003860A (es)
NI (1) NI201800043A (es)
PE (1) PE20181331A1 (es)
PH (1) PH12018500650A1 (es)
SV (1) SV2018005657A (es)
TN (1) TN2018000090A1 (es)
WO (1) WO2017055530A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108822103A (zh) * 2018-07-28 2018-11-16 刘凤娟 一种咪唑并[4,5-b]吡啶化合物及其制备方法和应用
CA3118093A1 (en) * 2018-09-28 2020-04-02 Arizona Board Of Regents On Behalf Of The University Of Arizona Small molecule inhibitors of dyrk1/clk and uses thereof
EP3873608A1 (en) 2018-10-31 2021-09-08 Gilead Sciences, Inc. Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
CA3117556A1 (en) 2018-10-31 2020-05-07 Gilead Sciences, Inc. Substituted 6-azabenzimidazole compounds as hpk1 inhibitors
TWI826690B (zh) 2019-05-23 2023-12-21 美商基利科學股份有限公司 經取代之烯吲哚酮化物及其用途
CN114786673A (zh) * 2019-09-11 2022-07-22 普莱鲁德疗法有限公司 Cdk抑制剂及其作为药物的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015021549A2 (pt) * 2013-03-13 2017-07-18 Abbvie Inc inibidores de piridina cinase cdk9

Also Published As

Publication number Publication date
CA2999935A1 (en) 2017-04-06
BR112018006157A2 (pt) 2018-10-09
JP2018535931A (ja) 2018-12-06
NI201800043A (es) 2018-06-21
PH12018500650A1 (en) 2018-10-01
CU20180028A7 (es) 2018-07-05
FR3041639A1 (es) 2017-03-31
HK1255804A1 (zh) 2019-08-23
MX2018003860A (es) 2018-08-16
US20180273528A1 (en) 2018-09-27
TN2018000090A1 (en) 2019-07-08
KR20180054858A (ko) 2018-05-24
CO2018003473A2 (es) 2018-07-10
DOP2018000083A (es) 2018-10-15
EA201890821A1 (ru) 2018-10-31
CR20180181A (es) 2018-06-22
CN108137581A (zh) 2018-06-08
MA43020A (fr) 2018-08-08
IL258341A (en) 2018-05-31
ECSP18023253A (es) 2018-04-30
CL2018000783A1 (es) 2018-09-21
EP3356363A1 (en) 2018-08-08
PE20181331A1 (es) 2018-08-20
FR3041639B1 (fr) 2019-01-25
AU2016333505A1 (en) 2018-04-19
WO2017055530A1 (en) 2017-04-06

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