SV2002000466A - ACAT CARBOXIALQUILETER-INHIBITOR COMBINATIONS - Google Patents

ACAT CARBOXIALQUILETER-INHIBITOR COMBINATIONS

Info

Publication number
SV2002000466A
SV2002000466A SV2001000466A SV2001000466A SV2002000466A SV 2002000466 A SV2002000466 A SV 2002000466A SV 2001000466 A SV2001000466 A SV 2001000466A SV 2001000466 A SV2001000466 A SV 2001000466A SV 2002000466 A SV2002000466 A SV 2002000466A
Authority
SV
El Salvador
Prior art keywords
acat
carboxialquileter
formula
rent
inhibitor combinations
Prior art date
Application number
SV2001000466A
Other languages
Spanish (es)
Inventor
Donna Lee Zobel
Bruce Jeffrey Auerbach
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of SV2002000466A publication Critical patent/SV2002000466A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

LA INVENCION ES UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN CARBOXIALQUILETER QUE REDUCE TRIGLICERIDOS Y LDL Y ELEVA EL HDL Y UN INHIBIDOR DE ACAT QUE MEJORA LA DISLIPIDEMIA EN MAMIFEROS, DICHA COMPOSICION ES UTIL PARA TRATAR LA DISLIPIDEMIA Y SINDROMES ISQUEMICOS Y PARA PREVENIR O RETARDAE EL COMIENZO DE ATAQUES CARDIACOS.LOS CARBOXIALQUIETERES TIENEN LA FORMULA 8 VER FORMULA), EN DONDE Y1 E Y2 INCLUYEN COOH, R1, R2, R3 Y R4 PUEDEN SER ALQUILO, Y N Y M SON NUMEROS ENTEROS DE 2 A 9; Y LOS INHIBIDORES DE ACAT TIENEN LA FORMULA ( VER FORMULA ), EN DOENDE R ES HIDROGENO, X ES O, R1 Y R2 SON FENILO SUSTITUIDO, E Y ES ALQUILOTHE INVENTION IS A PHARMACEUTICAL COMPOSITION THAT INCLUDES A CARBOXIALQUILETER THAT REDUCES TRIGLICERIDES AND LDL AND ELEVATES THE HDL AND AN ACAT INHIBITOR THAT IMPROVES DISLIPIDEMIA IN MAMIFEROS, SUCH COMPOSITION IS USEFUL TO TREAT THE DISTRICT AND COMPLETE DISMISSION. CARDIAC ATTACKS. CARBOXIALQUIETERES HAVE FORMULA 8 SEE FORMULA), WHERE Y1 AND Y2 INCLUDE COOH, R1, R2, R3 AND R4 CAN BE RENT, YNYM ARE WHOLE NUMBERS FROM 2 TO 9; AND THE ACAT INHIBITORS HAVE THE FORMULA (SEE FORMULA), IN DOENDE R IS HYDROGEN, X IS O, R1 AND R2 ARE SUBSTITUTED PHENYL, AND AND IS RENT

SV2001000466A 2000-06-07 2001-05-24 ACAT CARBOXIALQUILETER-INHIBITOR COMBINATIONS SV2002000466A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21005600P 2000-06-07 2000-06-07

Publications (1)

Publication Number Publication Date
SV2002000466A true SV2002000466A (en) 2002-04-03

Family

ID=22781424

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000466A SV2002000466A (en) 2000-06-07 2001-05-24 ACAT CARBOXIALQUILETER-INHIBITOR COMBINATIONS

Country Status (14)

Country Link
EP (1) EP1292363A2 (en)
JP (1) JP2003535125A (en)
AR (1) AR034255A1 (en)
AU (1) AU2001263003A1 (en)
BR (1) BR0111428A (en)
CA (1) CA2413906A1 (en)
GT (1) GT200100106A (en)
MX (1) MXPA02010762A (en)
PA (1) PA8518601A1 (en)
PE (1) PE20020265A1 (en)
SV (1) SV2002000466A (en)
TN (1) TNSN01085A1 (en)
UY (1) UY26752A1 (en)
WO (1) WO2001093845A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7387236B2 (en) 2001-10-09 2008-06-17 Delaware Capital Formation, Inc. Dispensing of currency

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2311356C (en) * 1998-01-28 2004-07-13 Warner-Lambert Company Method for treating alzheimer's disease

Also Published As

Publication number Publication date
JP2003535125A (en) 2003-11-25
TNSN01085A1 (en) 2005-11-10
EP1292363A2 (en) 2003-03-19
GT200100106A (en) 2002-05-20
BR0111428A (en) 2003-06-10
PA8518601A1 (en) 2002-07-30
MXPA02010762A (en) 2003-03-10
CA2413906A1 (en) 2001-12-13
WO2001093845A3 (en) 2002-10-10
AU2001263003A1 (en) 2001-12-17
AR034255A1 (en) 2004-02-18
PE20020265A1 (en) 2002-04-19
WO2001093845A2 (en) 2001-12-13
UY26752A1 (en) 2001-07-31

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