SU982658A1

SU982658A1 - Method of determining blood oxygenation level

Info

Publication number: SU982658A1
Application number: SU813237175A
Authority: SU
Inventors: Юрий Александрович Власов; Борис Михайлович Рогачевский; Анатолий Васильевич Якименко; Сергей Михайлович Смирнов
Original assignee: Новосибирский электротехнический институт
Priority date: 1981-01-12
Filing date: 1981-01-12
Publication date: 1982-12-23

Description

(54) СПОСОБ ОПРЕДЕЛЕНИЯ УРОВНЯ ОКСИГЕНАПИИ(54) METHOD FOR DETERMINING OXYGENAPIUM LEVEL

1one

Изобретение относитс к мединине и может быть использовано дл определени оксигенации крови.This invention relates to medine and can be used to determine blood oxygenation.

Известен способ определени оксигенации крови, заключающийс в том, что предварительно вз тую кровь больного располагают между источником света и фотоприемником . С фотоприемника снимают сигнал , пропорциональный оксигенации крови 1.There is a known method for determining blood oxygenation, which consists in placing patient's pre-drawn blood between the light source and the photodetector. A signal is taken from the photodetector that is proportional to blood oxygenation 1.

Недостатком этого способа вл етс необходимость заборов крови, при этом невозможно осуществл ть непрерывный контроль оксигенации крови длительный промежуток времени.The disadvantage of this method is the need for blood sampling, it is not possible to carry out continuous monitoring of blood oxygenation for a long period of time.

Известен также способ определени оксигенации крови, включающий измерение ее магнитного момента 2.There is also known a method for determining blood oxygenation, including the measurement of its magnetic moment 2.

Однако и этот способ св зан с вз тием проб крови. Кроме того, на получение результата уходит много времени.However, this method is associated with the collection of blood samples. In addition, the result takes a lot of time.

Целью изобретени вл етс осуществление способа in vivo и его ускорение.The aim of the invention is the implementation of the method in vivo and its acceleration.

Поставленна цель достигаетс тем, что согласно способу определени уровн оксигенации крови, включающему измерение ееThe goal is achieved by the fact that according to the method of determining the level of oxygenation of the blood, including the measurement of

КРОВИBLOOD

магнитного момента, измерение осуп1сствл ют сверхпровод щим измерителем градиента магнитного момента, при этом расно.чагают один из его чувствительных эломептои над легочной веной, а другой - над исследуемой точкой, и по разнице в показани х измерител определ ют степень oKcnixMiaции крови в исследуемой точке.magnetic moment, measurement of the residual by a superconducting measuring instrument for the gradient of the magnetic moment, in this case one of its sensitive electrons over the pulmonary vein, and the other over the test point, and the degree of oKcnixMia in the test point is determined.

Определение степени оксигенации крови определ ют с помощью прибора, содержа 0 щего криостат, заполненный жидким ге.мнем, в котором установлены два идентичных чувствительных элемента (сверхпровод щие петли диаметром менее 1 см), включенные навстречу друг другу и последовательно со сверхпровод щим трансформатором потока. Последний индуктивно св зан со сверхпровод щим квантовым интерференционным датчиком, соединенным через кабель с электронной частью схемы, выход которой подключен к регистрирующему прибору , проградированному в значени х степени оксигенации крови.The determination of the degree of blood oxygenation is determined using an instrument containing a cryostat filled with liquid gem., In which two identical sensitive elements (superconducting loops with a diameter of less than 1 cm) are installed, connected opposite to each other and in series with a superconducting flow transformer. The latter is inductively coupled to a superconducting quantum interference sensor connected via a cable to the electronic part of the circuit, the output of which is connected to a recording device that has been programed in terms of the degree of blood oxygenation.

Claims

In order to measure the stenosis of oxygenation, it is necessary to have a reference point at which the magnetic moment is known. As such a point, you can choose the pulmonary vein. The method is carried out as follows. The cryostat is positioned so that one sensor element is above the reference point, and the other is above the point of interest. The gradient of the magnetic moment between the reference and the studied points of the cardiovascular system is measured. Instrument readings correspond to the degree of blood oxygenation. In a device for determining the degree of blood oxygenation, external magnetic fields are compensated. In order to be able to measure the degree of oxygenation in the studied points located at different distances from the research institute from the reference one, you can either have a set of sensitive elements and with a different distance between them, or determine the degree of oxygenation for one fixed distance between sensitive elements at the studied point through any intermediate. The proposed method makes it possible to measure the degree of oxygenation even with a relatively small value of the magnetic moment of a unit volume of 10 A / m. Since the minimum magnetic field strength of 10 A / m measured by superconducting quantum interference sensors, as follows from the above estimates, the resolution of the proposed method for measuring the degree of oxygenation of less than 1% is quite attainable. Thus, a method for determining the level of oxygenation of the blood allows the method to be carried out in vivo and to obtain immediate results. Using the method, it is possible to continuously monitor the degree of blood oxygenation in a patient without disturbing the integrity of the skin. DETAILED DESCRIPTION OF THE INVENTION A method for determining the level of blood oxygenation, including measurement of its magnetic moment, characterized in that, in order to carry out the method in vivo and accelerate it, the measurement is carried out by a superconducting measuring instrument of the magnetic moment gradient, with one of its sensing elements arranged and the other is above the test point, and the degree of oxygenation of the blood at the test point is determined from the difference in the readings of the meter. Sources of information taken into account during the examination 1. Krepe E. P. Oxygeometry. 1959, p. 21-87.

2.News of medical instrumentation.-Works of VNIIMP, vol. 3, 1968, p. 175--177.