SU974981A1 - Method of synchronization of agricultural animal rut - Google Patents

Description

This invention relates to animal husbandry, in particular, to methods for synchronizing hunting in farm animals, mainly in mature chicks.

There is a known method for synchronizing hunting in farm animals, mainly in mature heifers, which includes a single sequential parenteral administration of progestogen 17c-oxyprgesterone capronate in the form of a 10-12% solution in a mixture of vegetable oil with benzene benzoate C 7:37 and at 17 18 day administration of chorionic gonadotropin in a dose of 1000-1500 HE / GOL., With estradiol benzoate at a dose of 5-10 mg / goal. l}.

The disadvantage of this method is the high cost of hormonal treatment of animals.

The aim of the invention is to reduce the cost of hormonal treatment of animals.

This goal is achieved by using metrogenol diacetate as a progestogen, which is administered in a dose of 100-140 mg per animal.

Example 1. Cows with known sexual cycles were administered subcutaneously once with mepregenol diacetate at a dose of 100 mg (7 goals) and at a dose of 140 mg of CU goals; per animal, with nine animals given the drug in the first half of the sexual cycle, and the rest in the second half of the cycle. When slaughtered on the 16th day after the injection of mepregenol diacetate in only one of 17 cows

10 5.9%) fresh ovulation was found, and predvulatory follicles were found in the ovaries of the remaining 16 cows (94.1%). The effect of a single parenteral administration of meperpregenol diacetate on the functional state of the ovaries of the cows is given in Table. one.

From tab. 2, it can be seen that treatment of cows with pregeneral diacetate for up to 20–100-140 mg per animal inhibits ovulation in approximately 94% of animals for at least 16 days.

Example 2. In the first production of a poor experience, 12 hells of a similar age were treated with mepregene diacetate at a dose of 140 mg per animal subcutaneously and after 18 days with intracranial chorionic

30 gonadotropin dose; 1500 IU / goal.

In combination with estradiol baseoatom at a dose of 10 mg / goal. All heifers (100% J hunted for 3 days after the last treatment. After the first insemination, 5 were fertilized (.41.6% of 12 heifers. Unfertilized heifers re-hunted 17-18 days later, of which after insemination 4, i.e., for two consecutive hunts, 9 heifers fertilized, which is 75-6 of the total number of treated animals.

Example 3. In the second production experiment, we treated 20 heifers of a similar age of mepregene with diacetate at a dose of 140 mg per animal subcutaneously and after 18 days intramuscularly with chorionic gonadotropin at a dose of 1000 IE / dgol. in combination with estradiol benzoate at a dose of 5 mg / goal. All heifers (100% 7 hunted for 3 days after the last treatment.) 8 (40%) and 8 heifers after the first insemination, 8 С 80% of the 20 treated animals fertilized heifers.

Example 4. In order to more accurately control hunting and ovulation in heifers, the effect of the time of the second hormonal treatment on the synchronism of the manifestation of the hunt and fertility of heifers was recognized. Telkag.1 was injected with once subcutaneously mapregenol diacetate at a dose of 140 mg, and then on day 14 (group 1) or on day 18 (group 2 was injected with chorionic gonadotropin at a dose of 1500 IU / goal, in combination with estradiol benzoate at a dose of 10 mg / goal. The three groups of the control group {3- group; hormones were injected parenterally. The hunting of heifers from the experimental and control groups was performed from 10 days after the last treatment.

The synchronicity of the manifestation of hunting and fertilization of heifers treated with hormonal preparations at various times after the administration of mepregene of diacetate is given in Table.

From tab. 2 shows that the accuracy of synchronization of hunting within 7 days

in the 1st experimental group, where the second treatment was carried out on day 14, was significantly higher than in the second and third groups (89.8% versus 75% and 24%).

The conducted tests of the proposed method showed that the treatment of heifers of mepregenol with diacetate in combination with chorionic gonadstrophy-. nom and estradiol benzoate allows

to obtain a high synchronization effect in sexually mature heifers and ensures normal fertilization in two consecutive sexual cycles.

15a, based on the data obtained, the following scheme for processing and insemination of heifers is recommended.

Over the month prior to insemination, 100 mg to 140 mg per animal in a mixture of vegetable oil, with benzyl benzoate (7: 3) are injected subcutaneously with mepregene once up to insects, with benzyl benzoate (7: 3, and 14–20 days after injection of mepregenol diacetate are injected

1000-1500 IE / Grl. chorionic gonadotropin in saline and 5-10 mg / goal. extraradio JIa benzoate in oil solution.

12 days after the second treatment, the hunt is started and

insemination. All hormonal treatments are carried out; ts before the start of heifer insemination. This allows the entire group of heifers to be seeded on average in 10-15 days, and not in 40-45 days,

how this is done in practice.

Due to the high gestagenic activity of mepregenol diacetate, the effective dose of this drug is

for parenteral administration, for hench sync ing, heifers are 10–15 times lower than 17 °. hydroxyprogesterone capronate. The cost of one hormonal treatment heifers 17 about {.- oxyprogesterone

capronate is about 10 rubles, and mepregene by diacetate is 2.2 rubles. Therefore, the economic efficiency of hormonal treatment in a single parenteral administration

Mepregenol diacetate, higher than 17s -roxyprogesterone capronate by 7.8 rubles per each treated animal.

Table 1

Claims (1)

Claim The method of synchronizing hunting in farm animals, mainly in mature heifers, including a single sequential parenteral administration of progestogen and chorionic gonadotropin with estradiol benzoate, about t and. characterized in that, in order to reduce the cost of processing ⁴⁵ , mepregenol diacetate, which is administered at a dose of 100-140 mg per animal, is used as a progestogen. ι Sources of information, 50 taken into account during the examination 1. USSR author's certificate No. 676284, cl. A 61 K 37/24, 1975.