SU761456A1 - Method of tripsin purification - Google Patents

Description

The invention relates to the field of organic synthesis, specifically, to a new chemical compound 1- / 1 (2-hexyloxyethoxy) ethoxy / -3- (piperidino) propanol-2 as a flotation reagent. This property suggests the possibility of using the compound in the mining industry.

Such flotation reagents as cresol, pine oil [1] and [2] are known.

These flotation reagents have a number of disadvantages such as high toxicity and cost.

Also known flotation agent, which is a mixture of alcohols pyran and dioxane series, the so-called (T-6b) £ 1] and [2].

The disadvantage of flotation reagent is its low efficiency.

The purpose of the invention is the creation of a highly effective flotation reagent.

This property is determined by the new chemical structure of the formula

from ₆ n

_1E osn (sn _a ) osn ₂ sn ₂ osn ₂ sn dn sn ₂

ten

15

20

25

Shenny, transparent liquid with a faint amine odor, stable in storage and perfectly soluble in most organic solvents, mol. weight 331; boiling point 159-161 ° C; n "1.4b05; c |" 0.9790.

1- / 1- (2-hexyloxyethoxy) ethoxy /

-3- (piperidino) propanol-2-'is obtained by the interaction of epoxy-acetal with a secondary amine. The reaction is carried out without solvents and catalysts, by heating an equimolar mixture of piperidine with acetyldehyde hexylglycidyloxyethoxyethyl acetal acetaldehyde at 60-70 ° C

The yield of the target product is close to quantitative. Almost after the completion of the reaction, individual hydroxyaminoacetal is obtained, which does not require special purification, although if necessary it can be further purified by distillation.

The composition and structure of 1- / 1- (2-hexyloxyethoxy) ethoxy / 3- (piperidino) propanol-2 are proved by elemental analysis and IR-spectroscopy.

In the IR spectrum of the compound, there are no characteristic frequencies of the oxide cycle (915, 1250, 3070 cm ' ¹ ),

but there is an absorption band of ΟΗΊ group (3450 cm).

he

1- / 1- (2-hexyloxyethoxy) ethoxy / -3 (piperidino) propanol-2 - slightly red 30

3 761466

Note ρ ....... 1. Synthesis of 1- / 1- (2hexyloxyethoxy) ethoxy‘-3-piperidino propanol-2. A mixture of 30 g

(0.122 m) heceylglycidyloxyethoxyethyl acetaldehyde and 10.4 g (0.122 M) piperidine are heated at 70 ° C for 4 h. By fractionation in a. 38.8 g of 96% 'of the desired product was isolated under vacuum with a boil of 159-161 ° C, η _about 1.4605; ό 0.9790 MN _C Found 92.7; calculated 94.0

Found,%: C 66.03; H 11.03;

N 4.16. ......................

C18 Nuu N04.

Calculated,%: C 65.25; H 11.18;

N 4.23.

Example 2. The test results of 1- / 1- (2-hexyloxyethoxy) ethoxy / -3- (piperidino) propanol-2- as a flotation reagent.

Test method.

For experiments, the initial sample (with a particle size of 2.0 mm and a weight of 125 g) is ground in a ball mill to 70% of a class of 0.063 mm. Flotation of the crushed product is carried out in a laboratory typewriter mechanical type with a capacity of 0.75 liters. The experiments are carried out according to the selective flotation scheme under the following reagent mode.

Grinding:

c _ianists d sodium, g / t 200

Zinc vitriol, g / t 200

Primary Lead Flotation:

Sodium Sulfur, g / t 50

Potassium butyl xanthohexate, g / t 15

Blowing agent

(variable flow), g / t 10-100

Basic zinc flotation:

Lime, kg / t

four

Copper sulphate, g / t 500

Potassium butyl xanthate, g / t 75

Frother (variable flow), g / t 10-100

- 1- / 1- (2-hexyloxyethoxy) ethoxy / ⁵ -3- (piperidino) propanol-2 was tested as a flotation agent on lead-zinc ore from the Akatuyevsky deposit of the Nerchinsk polymetallic plant. .The results are compared with the results of experiments using the T-66 blowing agent used at the beneficiation plant. Optimal flotation results using T-66 are achieved at a flow rate of 30 g / t. The total extraction of 15 metals in the concentrates of the same name is 172.02% '(see tab. 1).

1- / 1- (2-hexyloxyethoxy) ethoxy / -3- (piperidino) propanol-2 shows good foaming properties already 20 at a flow rate of 10 g / ton of ore, giving a total metal recovery of 178.06% of the same name

(see tab.2), and T-bb at the same expense - 169.53 (see Table 1).

25 Using 1- / 1- (2-hexyloxyethoxy) ethoxy / -3- (piperidino) propanol-2 as a flotation reagent, the recovery is higher; than with the T-66, at 8.29%. With an increase in flotation reagent consumption, the flotation selectivity ³⁰ does not decrease. At the same time, the consumption of 1- / 1- (2-hexyloxyethoxy) ethoxy / -3 (piperidino) propanol-2 is 3 times less. Thus, the use of 1- / 1- (2-hexyloxyethoxy) ethoxy / -3- (piperidino) propanol-2 as a flotation reagent increases the efficiency of the flotation process with the least consumption.

Table 1

The results of flotation using t-6b as an injector

Products enrichment Output, % Content, Extract, Consumption a driver, g / t Total metal recovery % % Pb Ζη Pb Ζη Pb concentrate 3.58 41.89 2.51 65.06 1.87 ten Pb-prom. product 1.64 19.04 3.95 13.54 1.35 ten Ζη-concentrate 11.18 1.41 32.55 6.84 75,89 ten 169.53 Ζη- prom. product 9.68 1.33 7.45 5.58 15.04 ten Tails 73.92 0.28 0.38 8.98 5.85 Original ore 100 2.31 4.80 100 100 Pb concentrate 5.49 37.02 1.86 76.17 2.16 thirty

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Continued table. ι

Output, Content, Extract, Consumption Sum ^ · Products % % 1 ¹ % foaming This is due to enrichment ---------- X .--- ------------- vatel attraction Pb Ζη Pb .. [. Ζη g / t metals

Pb-prom. “·. ·

product 5.40 3.60 3.06 7.29 3.51 ’ Ζη-concentrate 15.74 1.28 26,12 7.55 87.25 thirty 172.02 Ζη-prom. product 3.55 1.26 1.74 1.67 1.31 Tails 69.82 0.28 0.39 7.32 ’ 5.77 Original ore 100 2.67 4.71 100 100 Pb concentrate 6,69 28.28 1.76 71.50 2.43 60 ·. . - -Ζ- Pb-prom. product 8.46 3.40 2.63 10.86 4.59 2.P-concentrate 17.88 1.24 23,17 8.37 85.45 60 169.98 Ζη-prom. product 5.16 1.41 2.05 2.74 2.18 Tails 61.81 0.28 0.42 6.53 5.33 Original ore 100 2.65 4.85 100 100 . · · Pb concentrate 16.44 12.96 2.66 82.70 10.22 100 167.68 Pb-prom. product 2.64 3.00 3.10 3.07 1.91 2c-concentrate 11.08 1.24 30.36 5.33 78.61 100 Ζη-prom. product 4.23 1.08 3.33 1.77 3.29 Tails 65.61 0.28 0.39 7.13 5.97 Original ore 100 2.58 4.28 100 100 four T but b l and c a 2 The results of flotation using as in 1- / 1- (2-hexyloxyethoxy) ethoxy / -3- (piperidino) sprayer propanol-2 Products enrichment OUTPUT, % Content, % Extract % R Consumption blowing agent, g / t Total metal recovery Pb Ζη Pb Ζη

Pb concentrate 4.75 45.64 1.91 82.24 2.83

3.62 5.75 2.24 7.89 2.52 10

Rb-prom

product

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Products

enrichment

Output, %

Content%

Extract,

%

Continuation of table 2 -------- Ras- Summarr

Ζη

Pb

Ζη

blowing agent stroke, g / t

metal extraction

7.p-concentrate 18.76 '0,56 14.0 3.98 ’82,02 178.06 7. η - prom. product 5.56 0.62 3.41 1.30 5.91 Tails 67.31 0.18 0.32 4.59 6.72 Original ore 100 2.63 3.20 100 100 Pb concentrate 4.51 48.31 1.99 83.22 2.86 Pb-prom. product 2.90 6.36 3.16 7.04 2.92 178.60 concentrate 14.01 0.68 19.00 3.64 84,89 thirty prom. product 4.83 0.56 2.24 1.03 3, 45 Tails 73.75 0.18 0.25 5.07 5.88 Original ore 100 2.618 3,135,100 100 concentrate 5.56 40.26 2.91 82.23 4.92 prom. product 3.39 6.06 3.24 7.55 . 3.34 concentrate 11.13 0.93 24.00 3.80 81.31 60 175.63 prom. product 8.15 0.56 1.83 1.68 4.54 Tails 71.77 0.18 0.27 4.74 5.89 Original ore 100 2,722 3.285,100 100 concentrate 4.41 48.32 2.33 81.77 3.27 prom. product 2.73 8.18 3.07 8.56 2.68 concentrate 18) 86 0.62 14.0 4.48 84.14 100 176.73 prom. product 2.89 1.0 1.91 1.40 1.76 Tails 71.11 0.15 0.36 4.09 8.15

Original Ore 100

2,606 3,138,100 100

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Claims (1)

Claims 1- [1- (2-hexyloxyethoxy) ethoxy] -3 (piperidino) propanol-2 of formula with ₆ N ₀ OCH (CH _a) OCH ₂ CH ₂ CH ₂ -CH OSCh _and "L Y OH as a flotation agent.