SU689598A3 - Rodenticide composition - Google Patents

Description

(54) RODENTICIDAL COMPOSITION a) the reaction of an aniline compound of the general formula (II) in which —Kb is hydrogen, methyl, ethyl or propyl; RI-Rs are as defined above, with a 2-halogen-5-nitrobenzotrifluoride compound of the general formula (PP in which X is halo, and R is hydrogen or nitro, provided that Re and at least one of Rj and Cs is hydrogen, when Rr is a nitro group; b) N-alkylation of the compound obtained in step a) when Re is hydrogen; c) nitrating the compound obtained in step b) when R is hydrogen; d) if it is necessary to halogenate the compound obtained in step c), which lacks the desired halogen substituents. To reduce the population of rats or mice, an effective amount of the ropeptide composition of these compounds is applied to the places of their permanent residence. All of the listed compounds are referred to as diphenylamines for consistency and clarity, although some compounds may be called differently by the nomenclature rules. The following are specific compounds of the indicated general formula (I): 2,6-dibromo-4-chloro-y-methyl-2,4-dinitro-6-trifluoromethyldiphenylamine; 2-bromo-4 - chloro-N - ethyl-2,4 - dinitro-6 trifluoromethyldiphenylamine; 2,4-dichloro-M-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine; 2,6-dibrop-4-cyano-N - methyl 2,4-dinitro-6-trifluoromethyldiphenylamine; 2-chloro-2,4-dinitro-M-propyl - N-4, Qbis- (trifluoromethyl) -diphenylamine; N-ethyl-2,6 - dibromo-4-iodo-2,4-dinitrob-trifluoromethyldiphenylamine; M-propyl-2,6 - dichloro-2,4,4 - trinitro-6 trifluoromethyldiphenylamine; 2-bromo-6-chloro-2,4,4-trinitro-M-propyl-trifluoromethyl diphenylamine; 4-bromo-2-chloro-N-methyl-24-dinitro-6 trifluoromethyldiphenylamine; 2,4-dibromo-6-chloro-M-ethyl-2,4-dinitrob-trifluoromethyldiphenylamine; 2-bromo-6-chloro-y-methyl-2,4-dinitro-4,6bis-bis (trifluoromethyl) -diphenylamine; 2-chloro-N-methyl-2,4,4-trinitro-6-trifluoromethyldiphenylamino; fluoromethyldiphenylamine; 2,6-dibromo - 4-iodo-M-methyl-2,4-pitro-6 2.6-ibppm - 4-ypt-M-mrtil-94.-pitp-Vtrifluoromethyl-diphenylaminnn; 1M-methyl-2,4,6 - trichloro-2,4-dinitro-6 trifluoromethyldiphenylamine; 2,6-dibromo-N-methyl-2,4,4-trinitro-6 trifluoromethyldiphenylamine; N-ethyl-2-bromo-2,4-nitro-4-6-bys- (trifluoromethyl) -diphenylamine; 2,6-dibromo-4-cyano-2,4-dinitpo-N-propyl-b-trifluoromethyldiphenylamine; 2,4,6-trichloro-2,4-dinitro-N-propyl-6 trifluoromethyldiphenylamine; 2,6-dibromo-4-chloro-y-ethyl-2,4-dinitroblufluoromethyldiphenylamine; 2,6-dichloro-y-ethyl-2,4-dinitro-4,6-bis (trifluoromethyl) -diphenylamine; 2,6-dibromo-y-methyl-2,4-dinitro-4,6bis- (trifluoromethyl) -diphenylamine; 2-chloro-4-iodine - N-methyl-2,4-dinitro-6 trifluoromethyldiphenylamine; 2,6-dichloro-4-cyano-M-ethyl-2,4-dinitrob-trifluoromethyldiphenylamine; 2,4-dibromo-2,4-dinitro - N-propyl-b-trifluoromethyldiphenylamine; 4-bromo-2-chloro-N-ethyl-24-dinitpo-6-trifluoromethyldiphenylamine; 2-chloro-4-cyano-y-methyl-2,4-dinitro-6 trifluoromethyldiphenylamine; 2-bromo-M-methyl-2,4,4-trinitro-b-trifluoromethyldiphenylamine; 2-chloro-4-iodo-2 4-dinitpo-N - propyl-6 trifluoromethyldiphenylamine; 2,6 - dichloro-N - ethyl - 2,4,4 - trinitro - 6 trifluoromethyldiphenylamine; 2-bromo-4,6-dichloro-M-ethyl-2,4-dinitrob-trifluoromethyldiphenylamine; 2-bromo-6-chloro-4-cyano-2,4-dinitro-Nnropyl-b-trifluoromethyldiphenylamine; 2,6-dichloro-M-ethyl - 4-iodo-2,4 - dinitro-6 trifluoromethyldiphenylamine; M-ethyl-2,6-dibromo-4 - chloro-2,4-dinitrob-trifluoromethyldiphenylamine; 2-chloro-4-cyano-2,4-dinitro-N-propyl-trifluoromethyldiphenylamine; 2-bromo-4-chloro-M-methyl-2,4-dinitro-6 trifluoromethyldiphenylamine; 2-chloro-2,4,4-trinitro-N-nronyl-b-trifluoromethyldiphenylamine; 2-bromo-N-ethyl-2,4-dinitro-4,6-5 "c (trifluoromethyl) -diphenylamine; 2 - bromo-N - ethyl-4 - iodine-2,4 - dinitro-6-trnfluoromethyldiphenylamine; 2,4-dichloro-N-ethyl-2,4-dinitro-b-trifluoromethyldiphenylamine; 2,4,6 - tribromo-N - ethyl-2,4 - dinitro-6 trifluoromethyldiphenylamine; N-propyl - 2-bromo-4-cyano-2,4-dinitrob-trifluoromethyldiphenylamine; M-ethyl-2,6-dichloro-2,4-dinitro-4,6 (trifluoromethyl) -diphenylamine; 1fgirims 1; -diphenylamine, 2-chloro-y-methyl-2,4-dinitro-4,6- (5 "GO V tt oA„ pttoggggg (/ 1 P, (trifluoromethyl) -diphenylamine;

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N-methyl-2-bromo-4-nod-2,4-dinitro-6 trifluoromethyldiphenylamine;

2-bromo-4,6-dichloro-y-methyl-2,4-dsntro-6-triFluoromethyl diphenylamine;

2-bromo-6-chloro-4-cyano-N-methyl-2,4-dipitro-b-trifluoromethyldipheylamine;

4-unario-N - methyl - 2,4 - dinitro-b-triftopmetil 1feiyl amine;

2-bromo-4-chloro-2.4 - dptpttro-N-propyl-btriFtophenylphenyl aryl:

M-ethyl-2,2,4-trinitro - b-trpfluoromethyldipheylamine;

K-methyl-2-bromo - 2,4.4 - trinitro-b-trifotopmethyldifoyl-amylamine:

2.6-dichloro-4-iodo-2 4-dinitpo-N-propyl-6-triftopmestidifeilamine;

2-bromo-6-chloro-y-methyl-2,4,4-triiroben-toifluoromethyl diphenylamine:

N-1troyl-4-bromo-2-chloro-2,4-diitro-6triFluoromethyldipheylamine;

4-bromo-2.6-dichloro-2.4 - diiitro-N-yropyl-b-triftopmethylphenylamine;

2, b-dibrom-2.4.4-trinitro - N-pronyl-btrifluoromethyl diphenylamine;

2-bromo-6-chloro-4-iodine - K-methyl-2.4-dinitrop-6-trifluoromethyl diphenylamine;

-9til-2.6-dichloro-4-1thiano-2,4-diiitro6-three (lopmethyl diphenylamine;

4-G1Pom-2.6 - dichlor-N-methyl - 2,4-dinitro-6-trifluoromethyl diphenylamine;

N-gropyl - 2.4-dibrom - 2.4 - dinitro-6trispilPepil min;

(pom-6-chloro-K-ethyl-4-iodo-2,4-diiitro-6-trifluoromethyl diphenylamine; 2-bopt-4-niano-X-ethyl-2,4-dinitro-6trgbtormetnl diphenylamine;

2,4 - dibromo-6-chloro - 2,4 - dinitro-N-napyl-b-trifluoromethyldiphenylamine;

2,4-dibromo-2,4-diiitro-N-propyl-brifluoromethyldipheylamine;

2-bromo-4-chloro-6, N-dimethyl-2,4-diitro-6-trifluoromethyl diphenylamine;

2,4-dichloro-3-methyl-2,4-dinitro-N-nroyl-b-trifluoromethyl diphenylamine;

2,4-dibromo-2,4-diiitro-N-iroyl-b, bbis- (trifluoromethyl) -diphenylamine;

4-bromo-2-chloro-l-ethyl-2,4-dinitro-6,6bis-trifluoromethyl) -diphenylamine;

2,6-dichloro-4, S - dimethyl - 2,4-dinitro-btrifluoromethyl diphenylamine;

2-bromo-4, b-dichloro-N-methyl-2,4-dinitro-3, 6-bg / s- (trifluoromethyl) -diphenylamine;

2,4, b-trichloro-3, N-dimethyl - 2,4-dinitrob-trifluoromethyl diphenylamine;

2,4-dibromo-M-ethyl-b-methyl-2,4-dinitrob-trifluorometi l diphenylamine;

4-6 ppm-2 - chlorine - 2,4-dinitro-N - propyl 3, 6-bms- (trifluoromethyl) -diphenylamine;

2, b-dibrom-2,4-dinitro-M-ironil-4, bbis- (trifluoromethyl) -diphenylamine;

N-ethyl-2,4-diiitro-3, 5, b-tris- (trifluoromethyl) -phenylamine;

2,4,6-tribromo-N-ethyl-3-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

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2, b-dibromo-4-chloro-M-ethyl-2,4-dinitro 3, b-bg c- (trifluoromethyl) -diphenylamine;

4-bromo-2, b - dichloro-N - ethyl-3-methyl-2,4-dinitro-b-trifluoromethyl diphenylamine; 2, b-dnbrom-X-ethyl -, 4-ethyl-2,4 - diiitrob-trifluorome nl diphenylamine;

2-bromo-4-chloro-2,4-diiitro-N-nroiyl6, Q-6uc- (trifluoromethyl) -diphenylamine;

2-bromo-b-chloro-3, N-dimethyl - 2,4-dinitro-6-trifluoromethyl diphenylamine;

2-bromo-4, b-dichloro-3-methyl-2,4-dinitroN-proyl-b-trifluoromethyl diphenylamine;

4-bromo-2-chloro-5, N-dimethyl-2,4-dinitro-b-trifluoromethyldipheylamine;

4-bromo-2, b-dichloro-N-methyl-2 4-dinitro-3, b-bg / s- (trifluoromethyl) -diphenylamine;

2-bromo-6-chloro-N-ethyl - 2,4-dinitro-4,6bis- (trifluoromethyl) -diphenylamine; 2,4-dichloro-CT-methyl-2,4-dinitro-3,6bis bis (trifluoromethyl) -diphenylamine;

2,4-dibromo-M-methyl-2 4-dinitpo-N-propyl-b-trifluoromethyldiphenylamine;

4-bromo-2-chloro-b, N-dimethyl-2,4-dinitro-b-trifluoromethyldiphennlamine;

2,4-dinromo-N-ethyl-2 4-dinitro-3,6-bis (trifluoromethyl) -diphenylamine;

2,4,6 - tribromo-2,4 - dinitro-N - propyl 3, b / gc- (trifluoromethyl) -diphenylamine; 2-bromo-4-chlorop-N-ethyl-3-methyl-2,4-dinitro-b-trifluoromethyl diphenylamine;

2,4, b-trichlorop-N-ethyl-2,4-dinitro-3,6bis-trifluoromethyl) -diphenylamine;

2, b-dibromo-4-chloro-3-methyl-2,4-dinitroN-iroyl-b-trifluoromethyldiphenylamine;

2-bromo-4-chloro-N-methyl-2,4-dinitro3, b-bg / s- (trifluoromethyl) -diphenylamine;

2, b-dichloro-2,4-dinitro-1ch1 - ironil. 4,6b "c- (trifluoromethyl) -diphenylamine; 2,4-dibromo-3,5-dimethyl-2,4-dinitro-Nyroyl-b-trifluoromethyldiphenylamine;

2, b-dichlorop-3.5, N-trimethyl - 2,4-dinitrob-trifluoromethyl dipheylamino;

2-bromo-4-chloro-N-ethyl - 3.5-dimethyl - 2,4 dinitro-b-trifluoromethyldiphenylamine;

4-bromo-2-hlop-3,5, N - trimethyl - 2,4-dinitro-b-trifluoromethyl diphenylamine;

4-bromo-1Я-methyl-2,4-dinitro-3,5, b-gris (trifluoromethyl) -diphenylamine; 2,4, b-trichloro-2,4-dinitro-N-nronyl 3, 5, b-trg / s- (trifluoromethyl) -diphenylamine;

2,4-dibromo-N-ethyl-2,4-dinitro-3,5,6tris- (trifluoromethyl) -diphenylamine;

2, b-dibrom-4-chlorop-N-ethyl - 2,4-dinitro 3, 5, b-trys- (trifluoromethyl) -diphenylamine;

2,4, b-TRIBROM-3,5, N-trimethyl - 2,4-dinitro-b-trifluoromethyl diphenylamine;

4-chloro-K-ethyl-2,4-dinitro-2,6-bis (trifluoromethyl) -diphenylamine; 4-bromo-2,4-diiitpo-N-propyl - 2, b-bns (trifluoromethyl) -diphenylamine;

2, b-dibrom-N-ethyl-8-methyl-2,4,4-trinitro-6-trifluoromethyldiphenylamine;

2-bromo-b-chloro-3, K-dimethyl - 2,4,4-trinitro-b-trifluoromethyldiphenylamine;

2,6-dichloro-N-ethyl-3-methyl-2,4,4-trinitro-b-trifluoromethyldiphenylamine;

2,6-dibromo-4-iiano-3-methyl-2,4-dinitpo-N — propyl-b — trifluoromethyldiphenylamine;

2-bromo-6-chloro-4-cyano-M-el-3-methyl2, 4-dinitro-6-trifluoromethyldiphenylamine;

2,6-dichloro-4-cyano-3, M-dimethyl-2,4-dinitro-b-trifluoromethylphenylamine;

2-bromo - 6-chloro - 2,4-dinitro - N-propyl4, 6-b “c- (trifluoromethyl) -diphenylamine;

2.6-dibromo-y-ethyl-2,4-dinitro-4,6-bis (trifluoromethyl) -diphenylamine;

2,6-dichloro-M-ethyl - 2,4-dinitro-4,6-byc (trifluoromethyl) -diphenylamine;

2, b-dibrom-M-methyl - 2,4,4-trinitro-3, bbis- (trifluoromethyl) -diphenylamine;

2-bromo-6 - chloro-N - ethyl-2,4,4-trinitro 3, 6-bass- (trifluoromethyl) -diphenylamine;

2,6-dibromo-4-cnano-M-ethyl - 2,4-dinitro3, b-bms- (trifluoromethyl) -diphenylamine;

2-bromo-6-chloro-2,4,4-trinitro-M-propyl 3, 6-bis- (trifluoromethyl) -diphenylamine;

2,3,5-trichloro-M-methyl - 2,4,4,6-tetranitro-6-trifluoromethyldiphenylamine;

2-bromo-M-ethnl-2,2,4-triiitro-b-trifluoromethyldiphenylamine;

4-chloro-2,4,4-trinltro-Y-propyl-b-trifluoromethyldiphenylamine;

2,4-Dibromo-K-ethyl - 2,46 - trinitro-5,6bis- (trifluoromethyl) -diphenylamine;

4-bromo-2-chloro-M-methyl-2,46-trinitrob-trifluoromethyldiphenylamine;

2,3,4,5,6-pentachlor-N-methyl - 2,4-dinitro-6-trifluoromethyldiphenylamine;

2,3,4,5,6-pentabrom-L1-ethyl - 2,4-dinitrob-trifluoromethyldiphenylamine;

4-bromo-2,5,6-trichloro-3-fluoro-2,4-dinitro - N - nronyl-b - trifluoromethyldiphenylamine;

2,3,5,6-tetrabrom - 4-fluoro-M - methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

3,5-dibromo-2,4, b-trichloro-2,4-dinitroN-propyl-b-trifluoromethyldiphenylamine;

2,3,5,6 - tetrachloro - N-ethyl - 4-iodo-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,4, b-tribromo-3,5-dichloro-N-methyl 2,4-dinitro-b-trifluoromethyldiphenylamine;

2,3,4, b-tetrachloro-N-ethyl - 5-fluoro-2,4-dinitro-b-trifluorodiphenylamine;

3-bromo-2,4,5, b-tetrachloro-N-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,3,6-tribromo-5-fluoro-4,4-iodo-2,4-dinitro-N-propyl-b-trifluoromethyldiphenylamine;

2,3,4,5-tetrachloro-b - fluoro-N - methyl - 2,4-dinitro-b-trifluoromethyldiphenylamine;

2,3,4,6-tetrachloro-N-ethyl-2,4-dinitrob-trifluoromethyldiphenylamine;

2,3,5,6-tetrabrom - 2,4 - dinitro - N-propyl-b-trifluoromethyldiphenylamine;

2,6 - lpbrom-3,5 - dichloro - M-ethyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,3,4 - tribromo-b - fluoro-M-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,3,4-trichlpr M-: e1yl-5-fluoro-2,4-dinitro-b-trifluoromethyldiphenylamine; 2.b-dibp-4-fluoro - N-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,4 - dichloro-3-fluoro - 2,4-dinitro-N-napropyl-b-trifluoromethyldiphenylamine;

2-bromo-4-chloro-b - fluoro-N - methyl 2,4-dinitro-b-trifluoromethyldiphenylamine;

2, b-dibromo-3-cbtor - 4 - iodo-2,4-dinitroN-proyl-b-trifluoromethyldiphenylamine;

2,3,6 - trichloro-4-fluoropne-N-methyl - 2,4-dinitro-b-tififluoromethyldiphenylamine;

2-chloro-M-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

3-bromo -, M-methyl - 2.4 - dinitro - b-trifluoromethyldiphenylamine;

2, b-dichloro-4-fluoro-2 4-dinitro-N - propyl-b-trifluoromethyldiphenylamine;

2,4,6-trihl-N-ethyl-3-fluoro-2,4-dinitro-6-trfluoromethyldiphenylamine;

4-bromo-2, b-dichloro-3-fluoro-N-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine; 2,4-dibromo-M-ethyl-b - fluoro-2,4-dinitrob-trifluoromethyldiphenylamine;

2, b-dichloro-4-cyano-3-fluorop-N-meti.n-2 4 dinitro-b-trifluoromethyldiphenylamine;

4-6pOM-N - ethyl - 9 /, 4 - dinitro-2, b-bass (trifluoromethyl) -diphenylamine;

4-11: iano-M-methyl-2,4-dinitro-b-triftopmethyldisenylamine;

2.b-d chloro-3-fluoro-M, 4-dimethyl-2,4-dinitro-b-trifluoromethyldiphenylamine; 2,4-dibrom-3-chloro-N-methyl - 2,4 - dinitro-6, 6-bms- (trifluoromethyl) -diphenylamine;

2,4,4-trinitro-M-propyl-b-trifluoromethyl diphenylamine;

3,4-dichloro-N-methyl - 2,4-dinitro-b-trifluoromethyldiphenylamine;

2, b-dphlor-3-fluoro-methyl-24,4-trinitro-b-trfluoromethyldiphenylamine;

4-iodo-M-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

4-bromo-M-methyl - 2,4-dinitro-3,5, b-grms (trifluoromethyl) -diphenylamine;

2, b-dichloro-M-ethyl-3-bromo-2,4-dinitro6, 4-bass- (trifluoromethyl) -diphenylamine; 3,5-dibromo-y-methyl - 2 4-dinitro-b-trnfluoromethyldiphenylamine;

2-bromo-4-chloro-b-fluorop-N, 3-dimethyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2, b-dichlor-N-methyl-2,4-dinitro-3,5,6tris- (trifluoromethyl) -diphenylamine;

N-methyl-2,4-dinitro-4,6-bis- (trifluoromethyl) -diphenylamine;

4-chloro-N - methyl-2,4 - dianitro-b-trifluoromethyldiphenylamine;

4-bromo-2-chloro-N-ethyl-b-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

3,5-dibrom-2-chloro-N-methyl - 2,4 - dinitro-b-trfluoromethyldiphenylamine;

2,4-D 1-chloro-M-ethyl-3-methyl-2,4, b-trintro-b-trifluoromethyldiphenylamine;

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2,3,4-tribromo-5-fluoro - 2,4,6-trinitro-propyl-b-trifluoromethyldiphenylamine;

2,2,4,4 - tetranntro-N-propyl t b-trifluoromethyldiphenylamine;

2,4,6-trichloro-3,5-difluoro-N-methyl-2,4-dinitro-b-trifluoromethylphenylamine;

2,4-dibromo-6-chloro-M-ethyl-3,5-difluoro2, 4-dinitro-6-trifluoromethyldiphenylamine;

2,4-dibromo-3,5-dichloro-Y - methyl - 2,4-dinitro-6, 6-bass - (trifluoromethyl) - diphenylamine;

2,4 - dichloro - N-ethyl - 3,5 - difluoro - 2,4,6trinitro-b-trifluoromethyldiphenylamine;

4-bromo-2-chloro-3,5-difluoro-6-methyl-2,4-dinitro-N-propyl-6-trifluoromethyldiphenylamine;

2,6-dibromo-3,5-difluoro-M-methyl - 2,4-dinitro-b-trifluoromethyl diphenylamine;

2,4 - dichloro-N - ethyl-3,5 - difluoro-2,4-dinitro-b-trifluoromethyldiphenylamine;

2,6-dichloro-3,5-difluoro-4-iodo-.M-methyl2, 4-dinitro-6-trifluoromethyldiphenylamine;

2,6-dichloro-4-piano-M-ethyl-3,5-difluoro2, 4-dinitro-6-trifluoromethyldiphenylamine;

2,6-dibromo-3,5-difluoro-2,4,4-trinitrome-propyl-6-tififluoromethyl phenyl amine;

2,4-dichloro-3,6-difluoro-N-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine;

2-bromo-4-chloro-3,6-difluoro-2,4-dinitroN-propyl-b-trifluoromethyldiphenylamine;

4-bromo-2-chloro-y-methyl-2,4-dinitrob, 6-bms- (trifluoromethyl) -diphenylamine;

2,4-dibromo-Y-ethyl-6-methyl-2,4-dinitrob-trifluoromethyl diphenylamine;

4-bromo-2,4, - dinitro-N - propyl - b-trifluoromethyl diphenylamine:

2,4-dibromo-y-ethyl-2,4-dinitro-b, b-bis (trifluoromethyl) -diphenylamine;

3,4-Dibromo-M-methyl-2,4-dinitro-b-trifluoromethyldiphenylamine.

The following compounds are preferred for the present invention:

2,4, b-trichloro-M - ethyl - 2,4 - dinitro-btrifluoromethyldiphenylamine:

2,4,6-trichloro-N-methyl-2,4-dinitro-6-trn fluorometi l diphenylamine:

2,4-dibromo-M-methyl - 2,4-dinitro-b-trifluoromethyldiphenylamine;

2.4-dibromo-b-chloro-M-methyl-2,4-dinitro-b-trifluoromethyl diphenylamine;

2,4,6-tribromo-M-methyl-2,4-dinitro-brifluoro methyl diphenylamine;

-methyl-2,4 - distro - 3, 5,6 - tris- (trifluoromer1l) -dife1T1Tlamin;

2,6-dibromo-4-chloro-M-methyl-2,4-dinitro-b-trifluoromethylphenylamine.

The usefulness of the invention has been investigated with the administration of compounds of the general formula (I) to rodents in laboratory experiments.

The first series of oats is carried out by mixing the compounds with food grains.

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rodents and feeding processed food to male white rats of the species Sprek-Daley. Used food has the following composition,%:

Yellow crushed corn 42, 3 Ground oats crushed 10.0 Wheatgrass 10.0 Soybean flour extracted with Dehulled18.0 solvent Unnursed dry milk5.0 Dry corn distilled2.5 Alfalfa flour dehydrated 2, 5 Dry whey 1.0 Fish meal 4, 0 Animal fat (beef) 2.0 Dicalcium Phosphate 0.5 Calcium carbonate 1.0 Salt 0.3 Mineral premix 0.2 Vitamin premix 0.6 Hydroxyl analog of methionine 0, 1

The compounds of general formula (I) are mixed with portions of the above mentioned food in the concentrations shown in the tables below. The control rats in each experiment were fed the same, but unprocessed food.

A treated group of 4-5 rats was fed each serving of processed food, providing drink and water in unlimited quantities. Each rat is observed after death or the end of each experiment; each experience lasts 10 days if the rats survive.

The following tables give the concentration of the compound in the food, the number of days after the start of feeding to the rats treated with PIII until each rat died, and the weight change (positive or negative) for each rat during the 10-day experiment.

As rodenticide use 0,0025 weight. % 2,4, b-trichloro-y-ethyl-2,4-dinitro-b-trifluoromethyl diphenylamine. The results are shown in Table. one.

Table 1

55

60

Compound 2,4.6 - trichloro-N - methyl-2,4-dinitro-b - trifluoromethyl-diphenylamine - 0.0015 weight %

65 The results are shown in Table. 2. t a l l II c a 2 Compound 2,4 - dnbrom-M-methyl - 2,4-di nitro - 6 - trifluoromethyldiphenylamine - 0.1 weight. % The results are shown in Table. 3. Table 3 The second series of experiments was carried out to the mice - Mus musculus. Compound No. 1 — 2,4-dibromo-6-chloro-M methyl-2,4-dinnitro-b-trifluoromethyldifine-nylamnn and compound N ° 2 — 2,4,6-three bromo-K-methyl-2,4 - dinitro-6 - trifluoromene diphenylamine take at 0.005 weight. % The results are shown in Table. 4. Table 4 Number (it is to death when using compound No. According to the tables, it is clear that the proposed compound is effective rodenticides even at low concentrations. The most valuable is that the compounds kill rats after some time, and not immediately. When HpeyViaraeMHX is used in WWII to reduce the population of rats or mice, these compounds are applied in places where they are kept in rats or mice. The time and place of application of the rodenticide compositions, as well as the carriers for them, are normal. zhayut Tacna harmful types Plays unov as house mouse (Mus musciiliis). Norwegian kpysa (Rattns narveeicus). black rat R. rattiis reftiis) domailtih kpovelnyh rats (R. of frusfivorusi. Belonog Myint GRegomvscus leucapiis). luggage rats of fNeoto cinerea), a field mouse (Microtiis pennsvlvanicusl. Corresponding regulation of the compound concentrations in rodentinidic compositions allows them to be used to reduce the populi of rats or mice, both by immediate poisoning of the animals and by chronic poisoning of them after 1-hour feeding by 1 h.). The lethal effect of the compounds in question is important for their ire. 1. Rats eat 5–50 g of food per day, mice - 1–5 g per day, in each case it depends on the age of the animal, its size and condition. HEALTH: A pest control specialist can determine the number of animals in a colony and apply the appropriate quantities of treated animals or other forms of animals to animal habitats to ensure that each animal has an effective amount of ira. Rodentinide compositions are administered as powders or with potable water. used in the same way as food-based compositions, making appropriate adjustments to account for the difference in the methods of administration of compositions to rodents. Rodenticidal compositions are based on inert carriers, which include ischemic products, drinking water and finely divided solid powders. Compositions based on food products that are, in particular, inert carriers may contain any edible substance, since rats and mice are all bottoms. For example, such compositions may consist of cereal, meat by-products, or fats. Grain niche products that can be used in rodenticidal compositions include substances such as oats for flour, crushed or crushed corn, soy products, wheat and wheat by-products, rice waste, etc. Any grain can be the basis for such compositions. To increase the zrit of the bait, sweetening and odor-enhancing agents can be added to it. Fat rodenticide baiting compositions are usually made from inert ingredients such as oil.