SU615936A1 - Method of measurement of electrophoretic transfer of high-molecular substances - Google Patents

Method of measurement of electrophoretic transfer of high-molecular substances

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Publication number
SU615936A1
SU615936A1 SU772453490A SU2453490A SU615936A1 SU 615936 A1 SU615936 A1 SU 615936A1 SU 772453490 A SU772453490 A SU 772453490A SU 2453490 A SU2453490 A SU 2453490A SU 615936 A1 SU615936 A1 SU 615936A1
Authority
SU
USSR - Soviet Union
Prior art keywords
measurement
molecular substances
electrophoretic transfer
substances
membranes
Prior art date
Application number
SU772453490A
Other languages
Russian (ru)
Inventor
Абрам Израйлевич Перцовский
Вячеслав Иванович Емелькин
Original Assignee
Ялтинский Научно-Исследовательский Институт Физических Методов Лечения И Медицинской Климатологии
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Application filed by Ялтинский Научно-Исследовательский Институт Физических Методов Лечения И Медицинской Климатологии filed Critical Ялтинский Научно-Исследовательский Институт Физических Методов Лечения И Медицинской Климатологии
Priority to SU772453490A priority Critical patent/SU615936A1/en
Application granted granted Critical
Publication of SU615936A1 publication Critical patent/SU615936A1/en

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Description

(54) СПОСОБ ИЗМЕРЕНИЯ аЛЕКТРОФОРЕТИЧЕСКОГО ПЕРЕНОСА ИЫСОКОМалЕКУЛЯР№4Х СОЕДИНЕНИЙ(54) METHOD OF MEASUREMENT OF ELECTROPHORETIC TRANSFER OF ISO COMPLEX # 4 COMPOUNDS

Изобретевие дтвосвтсг к. фвзвко хвми ческим методам всспедоБавЕ  лекарствев вого адеБтр(4 ореэа в ьожет быть всполь зов&но дл  комплексвог0 взмереввз агаеао трофоретвческого веревоса шлсокомопекуь :л рш и : соедвЕюввА напрвмер белкоВ| фер мевтов в т. о. В со1фемеввыд: 4 звко- хвмнчес1Шх мв тодах асслед1жанвв лекарственвого алео трофс еза првмевббют раапвчвые способы :определевв  пол воств в апектрофоретви ческ(й подвшкноств веществ, BSd6qpe рас вфнтел  в оптвмума крвдевтрацна BOAOJродвых вовов в растворвтепе, сраввевв  действв  раэвых авдов апектрвческах в т, д, 1 . Существующве Способы ПОДГОТОВКЕ рао творов а   взмеревв  алектррфоретвчео EOT о переноса фармакопогвческв активных веществ не првспособлены ки  определ ВИЯ у высокомодекул рвых соедвнеыий указанных аыше параметров в не позво д ют достаточно точно оценвть нх эпеа трофс етвческую подвнжвость« Известен способ копвчественвсого вам ренв  апеЕТрсх|)С тического переноса фар макшмжВчесЕН актввных веществ , В этом способе раствор всследуемого вещества, огранвчеввый ароввдаекелмв мембранами, размещают в Среде раств1 рнтел , затем провод т апектрофорез в ;iio окрнчавнВ его измер ют разввцу девтрадвв даввого вещества в раствс теле боковых отделов. Однако такой способ вмеет пс  решвоб тн в нзмеренв х за счет {даффузай всслв г дуемых веществ. Например, способ првем лём дла внзком0пекул1фных I веществ двф фузва которых через проницаемые мембр| Еы составл ет всего от вх алев рофоретвческой подвижности, но не расЯ считан Eta высокомолекул рные соедин& ВИЯ, медпенно движущиес  в апектрическом пше, вследствие чего диффузи  вх через 1фовнцаемые мембраны превышает апе трофцретнческую подвижность. Эта диффузи  еюе более усиливаетс  в процессе проб, что еще больше снижаетInventions to keep in touch with your family. - hvmnches1Shkh mv vodas asped1zhanvv medicinal aleo trofs ez p vm ov z ravvvvvy ways: having defined a floor east in akroforetvr zak (y podvshkostv substances, BSd6qpe ras vfntel into optvmuma krvdevtra tv zhar, BSd6qpe ras vfntel into optvmma krvdetrak vk zav, zdvkvtvv BS, in BSd6qpe ras vfntel s o in t, d, 1. Existing Ways of PREPARING solutions and creeping an EOT elektrforretvcheo about transferring pharmacopogical active substances do not have a way to determine WIA in the high-mode parameters of the above mentioned parameters, they are not sufficiently accurate, and you will not be aspiring. reputable quality to you all the aforementioned | | With the tical transfer of headlights made of active substances, In this method, the solution of the substance under investigation, the limiting aperture of membranes in membranes, is placed in the Medium , Then it is carried out by spectrophoresis; iio is measured; it is measured at a dilution of the pressure substance in the solution of the lateral parts. However, such a method can be solved in freezes due to {duffusive substances. For example, the method is now known for extra-specular I substances of dvf fuzva through permeable membranes | Ea is only due to the inlet of the alero rophoretic mobility, but the eta is not considered a high molecular weight compound & VIA, medically moving in the aperture line, as a result of which diffusion through the membranes exceeds the apertrophilic mobility. This diffusion is more enhanced during the sample process, which further reduces

SU772453490A 1977-02-09 1977-02-09 Method of measurement of electrophoretic transfer of high-molecular substances SU615936A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU772453490A SU615936A1 (en) 1977-02-09 1977-02-09 Method of measurement of electrophoretic transfer of high-molecular substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU772453490A SU615936A1 (en) 1977-02-09 1977-02-09 Method of measurement of electrophoretic transfer of high-molecular substances

Publications (1)

Publication Number Publication Date
SU615936A1 true SU615936A1 (en) 1978-07-25

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SU772453490A SU615936A1 (en) 1977-02-09 1977-02-09 Method of measurement of electrophoretic transfer of high-molecular substances

Country Status (1)

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SU (1) SU615936A1 (en)

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