SU393828A3 - - Google Patents
Info
- Publication number
- SU393828A3 SU393828A3 SU1651104A SU1651104A SU393828A3 SU 393828 A3 SU393828 A3 SU 393828A3 SU 1651104 A SU1651104 A SU 1651104A SU 1651104 A SU1651104 A SU 1651104A SU 393828 A3 SU393828 A3 SU 393828A3
- Authority
- SU
- USSR - Soviet Union
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5289169 | 1969-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU393828A3 true SU393828A3 (en) | 1973-08-10 |
Family
ID=10465723
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1496136A SU419026A3 (en) | 1969-10-29 | 1970-10-29 | METHOD FOR PREPARING THE SUBSTITUTED ISOTHYOL1 UCHEVIN1 The invention relates to the method of obtaining the derivatives of amides, in particular the substituted isothiourea, which has pharmacological activity. The proposed method for producing a substituted isothiourea of the general formula .- ^^ - (^ E,}, t ^ '(^^^^' "X_LASR ^ where X is hydrogen, lower alkyl, amino or lower alkylthio; b ^ 1; n - 2-5; R— hydrogen, Ci — 4-, alkyl, aryl, or aralkyl; R * is saturated or unsaturated Ci — Cb-alkyl or (CH2) mZ, where m is 1-3; Z is substituted or unsubstituted aryl, hydroxyl, carboxyl, alkyl ^ mino or cyano group; R and R ^ together can form a 5-membered ring; 2A together with the adjacent carbon and nitrogen atoms is an unsaturated 5-6 membered heterocyclic ring, based on the well-known alkylation reaction of group 5 - C = S and consists in the fact that the thiourea of the general formula /? NK. "South": '™' ^^ Agde A, X, B, n and R have the above meanings, are treated with a compound of general 15 of the formula R'Y, where R 'is as indicated above; Y is halo or hydroxyl, and the target is isolated the product is in the form of a salt or is converted into the base by known methods. 20 The starting thiourea is used as an acid addition salt, for example, with a halogen-hydrogen, sulfuric, picric or maleic acid, or is carried out in the presence of one of these acids. organic solvent, such as ethyl alcohol, dimethylformamide, or acetone. uyuschies isothiourea addition salts converted to the base in the processing 30 for example, potassium carbonate. |
| SU1651104A SU393828A3 (en) | 1969-10-29 | 1970-10-29 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1496136A SU419026A3 (en) | 1969-10-29 | 1970-10-29 | METHOD FOR PREPARING THE SUBSTITUTED ISOTHYOL1 UCHEVIN1 The invention relates to the method of obtaining the derivatives of amides, in particular the substituted isothiourea, which has pharmacological activity. The proposed method for producing a substituted isothiourea of the general formula .- ^^ - (^ E,}, t ^ '(^^^^' "X_LASR ^ where X is hydrogen, lower alkyl, amino or lower alkylthio; b ^ 1; n - 2-5; R— hydrogen, Ci — 4-, alkyl, aryl, or aralkyl; R * is saturated or unsaturated Ci — Cb-alkyl or (CH2) mZ, where m is 1-3; Z is substituted or unsubstituted aryl, hydroxyl, carboxyl, alkyl ^ mino or cyano group; R and R ^ together can form a 5-membered ring; 2A together with the adjacent carbon and nitrogen atoms is an unsaturated 5-6 membered heterocyclic ring, based on the well-known alkylation reaction of group 5 - C = S and consists in the fact that the thiourea of the general formula /? NK. "South": '™' ^^ Agde A, X, B, n and R have the above meanings, are treated with a compound of general 15 of the formula R'Y, where R 'is as indicated above; Y is halo or hydroxyl, and the target is isolated the product is in the form of a salt or is converted into the base by known methods. 20 The starting thiourea is used as an acid addition salt, for example, with a halogen-hydrogen, sulfuric, picric or maleic acid, or is carried out in the presence of one of these acids. organic solvent, such as ethyl alcohol, dimethylformamide, or acetone. uyuschies isothiourea addition salts converted to the base in the processing 30 for example, potassium carbonate. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4946307B1 (en) |
| DK (1) | DK140938B (en) |
| ES (2) | ES385015A1 (en) |
| FI (1) | FI56001C (en) |
| IE (1) | IE34882B1 (en) |
| IL (1) | IL35518A (en) |
| NO (1) | NO133197C (en) |
| PH (1) | PH10563A (en) |
| SE (1) | SE376613B (en) |
| SU (2) | SU419026A3 (en) |
| ZA (1) | ZA707151B (en) |
-
1970
- 1970-10-19 DK DK531370AA patent/DK140938B/en unknown
- 1970-10-19 IE IE1346/70A patent/IE34882B1/en unknown
- 1970-10-20 ZA ZA707151A patent/ZA707151B/en unknown
- 1970-10-22 SE SE7014260A patent/SE376613B/xx unknown
- 1970-10-23 IL IL35518A patent/IL35518A/en unknown
- 1970-10-28 FI FI2901/70A patent/FI56001C/en active
- 1970-10-29 SU SU1496136A patent/SU419026A3/en active
- 1970-10-29 NO NO4129/70A patent/NO133197C/no unknown
- 1970-10-29 ES ES385015A patent/ES385015A1/en not_active Expired
- 1970-10-29 SU SU1651104A patent/SU393828A3/ru active
- 1970-10-29 JP JP45095831A patent/JPS4946307B1/ja active Pending
-
1971
- 1971-01-08 ES ES387088A patent/ES387088A1/en not_active Expired
-
1973
- 1973-02-09 PH PH14382A patent/PH10563A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL35518A (en) | 1978-07-31 |
| FI56001C (en) | 1979-11-12 |
| PH10563A (en) | 1977-06-28 |
| FI56001B (en) | 1979-07-31 |
| IE34882B1 (en) | 1975-09-17 |
| JPS4946307B1 (en) | 1974-12-09 |
| DK140938C (en) | 1980-05-19 |
| DK140938B (en) | 1979-12-10 |
| SU419026A3 (en) | 1974-03-05 |
| NO133197B (en) | 1975-12-15 |
| ZA707151B (en) | 1971-07-28 |
| ES385015A1 (en) | 1973-03-16 |
| ES387088A1 (en) | 1973-06-16 |
| IL35518A0 (en) | 1970-12-24 |
| IE34882L (en) | 1971-04-29 |
| SE376613B (en) | 1975-06-02 |
| NO133197C (en) | 1976-03-24 |