SU201399A1 - METHOD OF OBTAINING 0-ALKYL-5-ALKYL-5- (R-ACYLOXY) -ETHYLTRITIOPHOSPHATE - Google Patents
METHOD OF OBTAINING 0-ALKYL-5-ALKYL-5- (R-ACYLOXY) -ETHYLTRITIOPHOSPHATEInfo
- Publication number
- SU201399A1 SU201399A1 SU1063881A SU1063881A SU201399A1 SU 201399 A1 SU201399 A1 SU 201399A1 SU 1063881 A SU1063881 A SU 1063881A SU 1063881 A SU1063881 A SU 1063881A SU 201399 A1 SU201399 A1 SU 201399A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- alkyl
- obtaining
- ethyltritiophosphate
- acyloxy
- pyridine
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 4
- 125000003107 substituted aryl group Chemical group 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Natural products CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- -1 R is alkl Chemical group 0.000 description 2
- 239000000370 acceptor Substances 0.000 description 2
- 150000001735 carboxylic acids Chemical class 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 2
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L mgso4 Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 125000000547 substituted alkyl group Chemical group 0.000 description 2
- HXUIDZOMTRMIOE-UHFFFAOYSA-N 3-oxo-3-phenylpropionic acid Chemical compound OC(=O)CC(=O)C1=CC=CC=C1 HXUIDZOMTRMIOE-UHFFFAOYSA-N 0.000 description 1
- ZEBOYYJFGMXNOZ-UHFFFAOYSA-N chloro-ethoxy-ethylsulfanyl-sulfanylidene-$l^{5}-phosphane Chemical compound CCOP(Cl)(=S)SCC ZEBOYYJFGMXNOZ-UHFFFAOYSA-N 0.000 description 1
- WVPKAWVFTPWPDB-UHFFFAOYSA-M dichlorophosphinate Chemical class [O-]P(Cl)(Cl)=O WVPKAWVFTPWPDB-UHFFFAOYSA-M 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 150000002903 organophosphorus compounds Chemical class 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Description
Насто щее изобретение относитс к способу получени не описанных ранее фосфорорганических соединений общей формулы:The present invention relates to a method for producing organophosphorus compounds not previously described with the general formula:
RS (RO) Р ( S) -S-CHaCHaOCOR,RS (RO) P (S) -S-CHaCHaOCOR,
где R - низший алкил, R - алкпл, замещенный алкил, арил или замещенный арил.where R is lower alkyl, R is alkl, substituted alkyl, aryl or substituted aryl.
Названные соединени получают взаимодействием диалкилдитнодихлорфосфатов с р-меркаптоэтиловыми эфирами карбоновых Кислот в присутствии акцепторов хлористого водорода, например, пиридина.These compounds are prepared by reacting dialkyl dinitol dichlorophosphates with the p-mercaptoethyl esters of carboxylic acids in the presence of hydrogen chloride acceptors, for example, pyridine.
При м е р. Получение 0-этил-5-этнл-5-(рфенокспацетоксиэтил )-тритиофосфата.An example. Preparation of 0-ethyl-5-ethnl-5- (p-phenoxpacetoxyethyl) tritiophosphate.
К раствору 0,05 г люль диэтилдитиохлорфосфата п 0,05 г-моль р-меркаптоэтилового эфира феноксиуксусной кислоты в 40 мл сухого бензола прибавл ют при перемешивании и температуре 45-50°С раствор 0,05 г-моль пиридина в 10 лгл бензола. Перемешивание нродолжают в тех же услови х в течение 2 час, реакционную массу охлаладают, хлоргидрат пиридина отфильтровывают, фильтрат промывают водой, сушат сульфатом магни .To a solution of 0.05 g lule diethyldithiochlorophosphate n 0.05 g-mol of phenoxyacetic acid p-mercaptoethyl ester in 40 ml of dry benzene a solution of 0.05 g-mol pyridine in 10 l of benzene is added with stirring and at a temperature of 45-50 ° C. Stirring is continued under the same conditions for 2 hours, the reaction mixture is cooled, pyridine hydrochloride is filtered off, the filtrate is washed with water, and dried with magnesium sulfate.
растворитель отгон ют в вакууме и получают целевой продукт, выход 91%, df 1,2290,the solvent is distilled off in vacuum and get the target product, yield 91%, df 1.2290,
2020
1,5541.1.5541.
Найдено, %: Р 8,29 и 25,37. CwH.iOiPSs.Found,%: P 8.29 and 25.37. CwH.iOiPSs.
Вычислено, %: Р 8,45 и 25,26. В аналогичных услови х получены другие соединени приведенной общей формзлы.Calculated,%: P 8.45 and 25.26. Under similar conditions, other compounds of the above general formula were obtained.
Пред м е т изобретени Prevention Invention
Способ нолучени 0-алкил-5-алкпл-5-(|5aцнлoкcи )-эtилтpитиoфocфaтoв общей формулы:The method of obtaining 0-alkyl-5-alkl-5- (| 5 acetones) -ethyltriophosphate of the general formula:
RS (RO) Р ( S) -S-CHaCHjOCOR,RS (RO) P (S) -S-CHaCHjOCOR,
где R - низший алкил, R - алкил, замещенный алкил, арил или замещенный арил, отличающийс тем, что диалкилдитиохлорфосфаты подвергают взаимодействию с р-меркаптоэтиловыми эфирами карбоновых кислот в присутствии акцепторов хлористого водорода, например, пиридина.where R is lower alkyl, R is alkyl, substituted alkyl, aryl or substituted aryl, characterized in that the dialkyl dithiochlorophosphates are reacted with the p-mercaptoethyl esters of carboxylic acids in the presence of hydrogen chloride acceptors, for example pyridine.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU201399A1 true SU201399A1 (en) |
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