SU1731228A1 - Disinfecting preparation and method for disinfecting objects of veterinary inspection - Google Patents

Abstract

The invention relates to the field of veterinary medicine and can be used in veterinary practice to carry out disinfection of veterinary objects in the event of infections. The aim of the invention is to increase the disinfection activity of the agent. The drug has the following composition, wt.%: Indanyl-o-cresol 13.0-16.0, orthocresol 2.5-2.9, caustic soda 9.2-9.6, sulfonic acid 2.3-2.7, sodium benzoate 2.5-2.9, water the rest. An aqueous solution of the preparation is treated with the surface of objects at a flow rate of 0.5-1.0 l / m2, a temperature of 15-21 ° C and an exposure time of 3.0-24.0 hours, depending on the type of infection pathogen. Reliable disinfection of livestock buildings occurs when the preparation is used in 2-3% concentrations with disinfection quality control for E. coli, 4% for staphylococcus, and 6% for tuberculosis. 2 sec. f-ly, 2 tab. It poorly penetrates contamination, which leads to poor-quality disinfection of disinfection objects. In terms of toxicological parameters, the proposed composition is moderately hazardous and belongs to hazard class III. The purpose of the invention is to increase the disinfection efficiency against pathogens of the third group of usV | CJ yu 00

Description

resistance, including pathogens of tuberculosis, increasing the stability of the drug.

The preparation is prepared, a solution in half the amount of water is caustic soda, indanyl-o-cresol, orthocresol, sulfonol, sodium benzoate, then water is added to 100%.

PRI me R 1. The drug composition, wt.%:

13.0 2.5 9.2 2.3 2.5 Else

obtained by mixing the components, has bactericidal activity against Escherichia coli pcs. 1257 at a concentration of 0.097 g / 100 ml (known composition - at a concentration of 1.449 g / 100 ml), in relation to mycobacterium tuberculosis, pcs. B-5 at a concentration of 0.190 g / 100 ml (the known composition is non-bactericidal).

PRI mme R 2. The optimal drug composition, wt.%:

l

14 2.7 9.4 2.5 2.7 Else

obtained by mixing the components, has bactericidal activity against Escherichia coli pcs. 1257 at a concentration of 0.068 g / 100 ml (known composition - at a concentration of 1.449 g / 100 ml), in relation to mycobacteria tuberculosis, B-5 at a concentration of 0.136 g / 100 ml (known composition non-bactericidal).

PRI mme rZ. The drug composition, wt.%:

45

16 2.9 9.6 2.7 2.9 Else 50

obtained by mixing the components, has bactericidal activity against Escherichia coli pcs. 1257 at a concentration of 0.097 g / 100 ml (known composition - at a concentration of 1.449 g / 100 ml), in relation to mycobacterium tuberculosis, pcs. B-5 in a concentration of 0.190 g / 100 ml (the known composition is non-bactericidal).

0

five

0

five

0

five

0

five

0

five

The preparation obtained according to Examples 1-3 is a uniform brown liquid that is miscible with water in any ratios.

Disinfection activity of the drug is provided by the introduction of indanyl-o-cresol in synergism with caustic soda. Due to the introduction of sulfonol into the preparation, its solutions penetrate well into the contaminants. The stability of the drug is due to the administration of sodium benzoate. The drug is stable for 1.5 years without reducing its bactericidal properties.

At the same time test samples 4-11, the composition of which is given in table. one.

The essence of the proposed disinfection method consists in treating the surfaces of livestock facilities and equipping them with a solution of a disinfectant substance, the preparation solutions being used at a concentration of 2.0-6.0 wt.%, The surfaces are treated at a flow rate of 0.5-1 l / m solution temperature of 10-30 ° C and exposure time of 3-24 hours

In livestock buildings after mechanical cleaning, wet disinfection with an aqueous solution of the preparation is carried out by applying the solution to the surface to be treated manually or using technical means for spraying liquids (hydraulic controls, sprays, disinfectants). Solutions of the preparation are prepared in water at a temperature of 15-21 ° C, which is necessary for maximum disinfecting effect.

PRI me R 4. When disinfecting with a working solution of a preparation of 2% spray concentration under a pressure of 2 atm, a solution temperature of 18 ° C and its consumption at the rate of 0.5 l / m2, exposure 24 hours, disinfection activity against intestinal sticks (pieces 1257) is 100% (the prototype is effective in 10% drug concentration at a flow rate of 1 l / m2).

EXAMPLE 5 When using solutions of 4% concentration with a flow rate of 0.5 l / m, an exposure time of 3 hours and a solution temperature of 15 ° C, the disinfection activity against Staphylococcus aureus (pcs. 209-P) is 100 % (prototype effective in 20% concentration at a flow rate of 1 l / m2).

EXAMPLE 6 When using solutions of 6% concentration at a flow rate of 1 l / m, an exposure of 24 hours and a temperature of 21 ° C, the disinfection activity against mycobacteria (pcs. B-5) is 100% (the prototype is ineffective ).

At the same time, the drug solutions are tested in other concentrations (see Table 2).

As studies show, reliable disinfection of livestock buildings occurs when the preparation is used in 2-3% concentrations while controlling the quality of disinfection in E. coli, 4% in staphylococcus and 6% in microorganisms related to 3- th group of devices, in this case bacteria of tuberculosis. At the same time, the consumption rate of the preparation solution is 0.5-1.0 l / m2, and the exposure time is 3-24 hours, depending on the type of microorganism.

The use of the proposed drug and its method of disinfection of objects of veterinary supervision can significantly reduce the cost of disinfection work, improve the quality of disinfection and at the same time destroy the causative agents of infectious diseases in the external environment, including microorganisms, related to the third group, particular pathogens of tuberculosis.

Claims (2)

1. Disinfectant preparation, including active substance, surfactant and water, characterized in that, in order to increase its effectiveness, indanyl-o-cresol, ortho-cresol, caustic soda, sodium benzoate are used as active substance, and as a surfactant - sulfonol in the following ratio of components, wt.%: Indanyl-o-cresol Orthocresol Caustic soda Sulfonol Sodium benzoate Water 13.0-16.0 2.5-2.9 9.2-9.6 2.3-2.7 2.5-2.9 Else 2. A method for disinfecting veterinary surveillance objects, including the treatment thereof with a disinfectant, characterized in that, in order to increase .effectiveness of the method for tuberculosis, as a disinfectant, use a preparation containing the following components, wt%: indanyl-o-cresol 13.0-16.0; orthocresol 2.5-2.9; sodium hydroxide 9.2-9.6; sulfonol 2.3-2.7; sodium benzoate 2.5-2.9; water is the rest, and surface treatment is carried out at a drug consumption rate of 0.5-1.0 l / m2, its temperature is 15-21 ° C and exposure time is 3-24 hours, depending on the type infectious agent. Table 1 table 2