SU1724272A1 - Method for treatment of patients with pyoperitonitis - Google Patents

Abstract

This invention relates to medicine, namely to surgery. The goal is to reduce mortality in the treatment of patients with purulent peritonitis of the spilled form. The goal is achieved by extracorporeal irradiation of the autologous blood of the patient with ultraviolet rays with a dose of incident radiation of 5.00-700 J / m2, for which blood is drawn from the abdominal aorta, and after irradiation it is administered directly to the orifice of the celiac trunk and superior mesenteric artery.

Description

This invention relates to the field of medicine, namely surgery.

The purpose of the invention is to reduce mortality in case of spilled forms of purulent peritonitis.

The method is carried out as follows.

A catheter is inserted into the aorta aorta, through which blood is taken at a rate of 1-4 mm per kg of body weight of the patient in a vial with 50 ml of physical solution and 2.5 hectares; After that, the blood is irradiated, then the blood is re-irradiated by pumping it into another empty sterile vial without a filter at a rate of i18 ml / min. After irradiation, a pear with a manometer is attached to the duct of the blood vial and pumped. blood in the catheter installed for infusion therapy to the mouth of the celiac trunk and superior mesenteric artery.

Sessions are conducted every other day, 3-5 sessions -1 owls per course. The dose of incident radiation is 500-700 J / m.

Note 1. Patient A, 56 years old, was admitted to the hospital with a diagnosis of a breakthrough of intraperitoneal abscess into the abdominal cavity, diffuse peritonitis. Surgery: laparotrmy, drainage of the abdominal cavity.

4 sessions of intra-arterial UBI of 3 Ml per kg of weight every other day were conducted. The first session before the ultraviolet irradiation of blood leukocytosis 10.3 109 / l, LII 8, immune complexes (IR) 200 units / ml. After 1 h after the ultraviolet irradiation of blood: leukocytosis 11, .x 10Vn, LII 4.8 IR 81 units / ml. The patient was in the intensive care unit for 7 days, after 27 days he was discharged from the clinic in a satisfactory condition.

PRI mme R 2. Sick V., 76 years old. The 2/3 of the stomach was resected. In the postoperative period has developed

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inconsistency gastroenteroanastosum mosaic spilled purulent peritonitis. Relaparotomy, drainage of the abdominal cavity. 3 sessions of blood ultraviolet irradiation were performed, intra-aortic 4 ml per kg of weight. After 6 days, the patient was transferred from the intensive care unit, another 21 days later she was discharged from the clinic.

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in a satisfactory condition. Before the first session of the UBI, blood leukocytosis was 12.7-109 / l, LII - 14.1, T-lymphocytes 19%, B-lymphocytes 17%, phagocytosis with latex 86%, JK-190 un.ml, immuno-globulins IgG 6, 37 rln} SL 2-, 46 g / l, 15 IgM 2.83 g / l. After the first session bvg one day: leukocytosis 9.0-10. / L, LII 7.2, T-lymphocytes 58%, B lymphocytes 21% ,. phagocytosis with latex 62%, PC 71 units / ml, IgG 13.0 g / l, IgA 2.46 g / l, IgM 1.99 g / l.

Within a day, the level of endotoxemia significantly decreased, the clearance of immune complexes increased, and the dynamics of immunity indices were favorable.

When peritonitis is poured, the microcirculation in the abdominal cavity is significantly impaired, in fact, the blood supply in such organs as peritoneal circulation is blocked.

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, chen, kidneys, intestines, etc. There is a peculiar phenomenon of robbery, reduced blood flow IB celiac trunk, mesenterial vessels and renal arteries.

When conducting intra-aortic UBI due to the well-known effect of UV-acid on blood viscosity, microcirculation in the abdominal organs and anti-inflammatory and detoxication is improved (the medicinal products during intra-aortic infusion therapy are delivered to the abdominal organs. Mortality decreased to 17 % from 40-70%.

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Claims (1)

Invention Formula A method of treating patients with purulent peritonitis, including electrocorporeal ultraviolet irradiation of blood, characterized in that, in order to reduce mortality in various forms of purulent peritonitis, blood is taken from the abdominal aorta for irradiation, and after irradiation is administered directly to the orifice of the celiac trunk and upper mesenteric artery. Invention Formula A method of treating patients with purulent peritonitis, including electrocorporeal ultraviolet irradiation of blood, characterized in that, in order to reduce mortality in various forms of purulent peritonitis, blood is taken from the abdominal aorta for irradiation, and after irradiation is administered directly to the orifice of the celiac trunk and upper mesenteric artery.