SU1708328A1 - Method for manufacturing vascular prostheses - Google Patents

Method for manufacturing vascular prostheses Download PDF

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Publication number
SU1708328A1
SU1708328A1 SU894718559A SU4718559A SU1708328A1 SU 1708328 A1 SU1708328 A1 SU 1708328A1 SU 894718559 A SU894718559 A SU 894718559A SU 4718559 A SU4718559 A SU 4718559A SU 1708328 A1 SU1708328 A1 SU 1708328A1
Authority
SU
USSR - Soviet Union
Prior art keywords
umbilical cord
artery
vascular prostheses
stud
bioprostheses
Prior art date
Application number
SU894718559A
Other languages
Russian (ru)
Inventor
Леонид Семенович Барбараш
Александр Сергеевич Криковцов
Original Assignee
Кемеровский государственный медицинский институт
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Application filed by Кемеровский государственный медицинский институт filed Critical Кемеровский государственный медицинский институт
Priority to SU894718559A priority Critical patent/SU1708328A1/en
Application granted granted Critical
Publication of SU1708328A1 publication Critical patent/SU1708328A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels

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  • Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

Изобретение относитс  к медицине и может быть использовано при изготовлении биологических сосудистых протезов из артерии пупочного канатика новорожденного. Цель изобретени  состоит в улучшении биомеханических свойств сосудистого протеза. Дл  достижени  цели артерию пупочного ка- ''натика выдел ют острым путем из тканей пуповины вместе с окружающим слоем варто- новой студени. Полученные предложенным способом биопротезы использованы в 10 зкспериментах на собаках и у 2 больных дл  протезировани  глубокой артерии бедра. Во всех случа х через год отмечена хороша  проходимость биопротеза с сохранением соединительно-тканной структуры оболочки. Способ рекомендован дл  внедрени  в практическое здравоохранение.The invention relates to medicine and can be used in the manufacture of biological vascular prostheses from the artery of the umbilical cord of a newborn. The purpose of the invention is to improve the biomechanical properties of a vascular prosthesis. In order to achieve the goal, the artery of the umbilical cord is extracted in an acute way from the tissues of the umbilical cord together with the surrounding layer of the warrant stud. The bioprostheses obtained by the proposed method were used in 10 experiments on dogs and in 2 patients for prosthetic deep artery of the thigh. In all cases, the patency of the bioprosthesis with the preservation of the connective tissue structure of the membrane was noted after a year. The method is recommended for implementation in practical health care.

Description

Изобретение относитс  к медицине, а именно к сердечно-сосудистой хирургии, и может быть использовано при изготовлении биологических сосудистых протезов из артерии пупочного канатика новорожденного .The invention relates to medicine, namely cardiovascular surgery, and can be used in the manufacture of biological vascular prostheses from the artery of the umbilical cord of the newborn.

Цель изобретени  - улучшение биомеханических свойств сосудистого протеза.The purpose of the invention is to improve the biomechanical properties of the vascular prosthesis.

Указанна  цель достигаетс  тем, что после моделировани  на мандрене соответствующего профил  артерию пупочного канатика выдел ют острым путем из тканей пуповины вместе с окружающим слоем вартоновой студени.This goal is achieved by the fact that after modeling the corresponding profile on the mandrel, the umbilical cord artery is extracted in an acute way from the umbilical cord tissues along with the surrounding layer of the vartone stud.

Пример. После отмывани  ткани пуповины от крови физиологическим раствором в просвет артерии ввод т буж-мандрен конической формы диаметром 2-4 мм. ПупочНый канатик помещают в раствор глютарового альдегида. После окончани  процесса консервации с помощью хирургических инструментов острым путем артерию выдел ют из элементов путчного канатика с участком окружающей ее вартоновой студени таким образом, чтобы толщина стенки была 1-1,5 мм. Мандрен удал ют, артерию помещают а сосуд с глютаровым альдегидом дл  хранени .Example. After washing the umbilical cord tissue from the blood with a saline solution, a conical-shaped bougé mandrin with a diameter of 2-4 mm is introduced into the lumen of the artery. The umbilical cord is placed in a solution of glutaraldehyde. After the end of the preservation process using acute surgical techniques, the artery is isolated from the elements of the cable with the surrounding Wharton stud surrounding it in such a way that the wall thickness is 1-1.5 mm. The mandrin is removed, the artery is placed and the vessel containing glutaraldehyde is stored.

Хронические зксперименты проведены на 10 собаках. Изготовленные предложенным способом биопротезы в сроки до 12 мес сохран ли структуру соединительнотканной оболочки, бьши проходимы. Формирование анастомозов значительно упрощалось, отсутствовало прорезывание швов. В клинической практике оперированы 2 больных. Биопротезы использованы дл  протезировани  глубокой артерии бедра (диаметром 3 мм). Через год биопротезы проходимы, функци  конечности сохранена .Chronic experiments were conducted on 10 dogs. The bioprostheses made by the proposed method for up to 12 months preserved the structure of the connective tissue sheath, being passable. The formation of the anastomoses was significantly simplified, there was no eruption of the seams. In clinical practice, 2 patients were operated on. Bioprostheses are used for prosthetics of the deep femoral artery (3 mm diameter). After a year, the bioprostheses are passable, the limb function is preserved.

Способ рекомендован дл  применени  в практическом здравоохранении.The method is recommended for use in medical practice.

317083284317083284

Claims (1)

Формула изобретени личающийс  тем, что, с целью улучшени The claims are in order to improve Способ изготовлени  сосудистого про-биомеханических свойств протеза, артериюA method of manufacturing vascular pro-biomechanical properties of the prosthesis, artery теза, включающий выделение элементов пу-пупочного канатика выдел ют вместе с окпочного канатика из тканей пуповины, о т -ружающим слоем вартоновой студени.A prosthesis, including the isolation of the elements of the umbilical cord, is separated from the umbilical cord, from the umbilical cord tissue, by the surrounding layer of the varton stud.
SU894718559A 1989-07-11 1989-07-11 Method for manufacturing vascular prostheses SU1708328A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU894718559A SU1708328A1 (en) 1989-07-11 1989-07-11 Method for manufacturing vascular prostheses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU894718559A SU1708328A1 (en) 1989-07-11 1989-07-11 Method for manufacturing vascular prostheses

Publications (1)

Publication Number Publication Date
SU1708328A1 true SU1708328A1 (en) 1992-01-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU894718559A SU1708328A1 (en) 1989-07-11 1989-07-11 Method for manufacturing vascular prostheses

Country Status (1)

Country Link
SU (1) SU1708328A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005176663A (en) * 2003-12-17 2005-07-07 Ikushu Fu Cell line for producing somatic cell
JP2006517102A (en) * 2003-02-11 2006-07-20 ダビース，ジヨン・イー Progenitor cells from Wharton's jelly of human umbilical cord

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент US № 3974526, кл. А 61 F 2/24' 1976. *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517102A (en) * 2003-02-11 2006-07-20 ダビース，ジヨン・イー Progenitor cells from Wharton's jelly of human umbilical cord
JP4790592B2 (en) * 2003-02-11 2011-10-12 ダビース，ジヨン・イー Progenitor cells from Wharton's jelly of human umbilical cord
JP2005176663A (en) * 2003-12-17 2005-07-07 Ikushu Fu Cell line for producing somatic cell

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