SU1692579A1 - Vaginal suppository for treatment of inflammatory diseases of cervix uterus - Google Patents

Abstract

This invention relates to medicine and relates to the treatment of inflammatory diseases of the cervix. The purpose of the invention is to increase the pharmacological activity. Vaginal suppository contains boric acid, glucose, sulfadimezin, honsurid, cocoa butter in certain quantities.

Description

This invention relates to medicine and relates to the treatment of inflammatory diseases of the cervix.

The purpose of the invention is to increase the pharmacological activity.

Example 1. Patient D., 21 years old (outpatient history number 160-84), went to the antenatal clinic with complaints of aching pain in the lower abdomen, mucous secretions from the genital tract. History 1 birth and 1 induced abortion. When viewed in the mirrors of the cervix with areas of geperemia. A colposcopy was performed, an ectopic cylindrical epithelium was detected, going out into the second zone of the vaginal part of the cervix with an abundant inflammatory vascular network. Cytological examination of cervical smear - type II, inflammatory process. Bacteriological examination of the cervical canal removed from the conditional pathogenic microflora. After a bimanual study, a diagnosis was made: endocervicitis, chronic bilateral adnexitis. The treatment was carried out by inserting into the vagina balls containing, g: boric acid 0.1, glucose 0.3; sulfadimezin 0,3; Honsurid 0.01; cocoa butter is the rest. Epithelization of the vaginal part of the cervix is over by the end of the 2nd week. The control bukisledovanie contents of the cervical canal microflora growth is not given. Cytologically determined cytogram type I, without features. The observation was carried out on a woman for 2 years. In the first year every 3 months, in the second year every 6 months. No recurrence of the disease was noted; the woman was removed from the dispensary observation.

Example 2. Ill With, 28 years old (outpatient card number 6-84). Appealed to the reception to the gynecologist with complaints of pain in the lower abdomen of the aching nature, giving in the area of the scissors. History 1 genera physiological and two artificial abortions. Colposcopic examination - endocervicitis, cervical smear cytology - type 2, inflammatory process. Bacterioscopy -3- degree of purity. Bacteriological examination of the contents of the cervical canal - E. Colli. Bimanualle C

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study - slightly enlarged and sensitive on both sides of the uterus subdigs -. The diagnosis is chronic bilateral adnexitis at the exacerbation stage, emdotseroitsit. The patient is recommended to use vaginal balls for 20 days, content, g: boric acid 0.05; glucose 0,3; sulfadimezin 0.1; Honsurid 0.01; cocoa butter - the rest. Clinically, improvement after 2 weeks was not observed, and after 3 weeks from the start of treatment, endochervicitis was observed. Bacterioscopically 3-degree purity of flora was determined. Taking into account the ineffectiveness of the therapy, vaginal balls were used, containing, g: boric acid 0.2; glucose 0,5; sulfadimezin 0.5; Honsurid 0.03; cocoa butter else. Disappearance of endocervicitis signs was noted by the 10th day from the start of treatment. In the control studies at the 2-4th week, after 3 and 6 months the growth of microflora was not observed, the disease recurrence was not revealed. After observing for 2.5 years, I am ill from follow-up.

Example 3. Ill R., 27 years old (outpatient history number 37/84). Examination of the cervix revealed changes characteristic of the endocervicitis. Colposcopic sites in the 1st and 2nd zone of the cervix ectopia of a cylindrical epithelium with a vascular network of inflammatory origin. Cytological examination is a type of inflammatory process. Bacteriological examination - St. epidermis IV Art. A bimanual examination of the internal genital organs indicated the presence of a chronic inflammatory process of the genitals. The patient is recommended to take vaginal balls containing, g: boric acid 0.1; glucose 0,3; sulfadimezin 1.0; Honsurid 0.05; cocoa butter - the rest, for 20 days. After taking the vaginal globules for 2 days, the patient complained of a burning sensation in the vagina, increased secretions. On examination, the vaginal mucosa is hyperemic, painful on vaginal examination, abundant leucorrhoea is noted. The condition is regarded as an allergic reaction to the high content of the components of the agent for the treatment of inflammatory diseases of the cervix of the uterus. Further reception of the vaginal balls is stopped and after 3 days of rest the administration of the proposed composition is started, g: boric acid 0.1; glucose 0,3; sulfadimezin 0.5; Honsurid 0.01; cocoa butter is the rest. No adverse reactions were noted during the entire course of treatment. The outcome is favorable: during the examination by the end of the second week, there were no inflammatory changes in the vaginal part of the cervix, the boundary of the multi-layered flat and cervical cylindrical epithelium was within the age norm. Microbial growth was not detected by bacteriological examination of the discharge from the cervical canal. Cytological smear confirmed the absence of inflammation in the cervix - type, cytogram without features. During the year of follow-up, recurrence of the disease .ie was detected.

The proposed remedy is more effective than the known one and has no side effect, which is reflected in the table.

Claims (1)

The proposed agent can be used for the treatment of inflammatory diseases of the cervix prepared before use (ex tern horn). Claims of the invention A vaginal suppository for the treatment of inflammatory diseases of the cervix uterus containing boric acid, glucose, cocoa butter, characterized in that, in order to increase its activity, it additionally contains sulfadimesin, chloiside in the following ratio of components, g: Borna acid 0,1-0,2 Glucose 0.3-0.5 Sulfadimezin 0,3-0,5 Honsurid0,01-0,03 Maslo cocoa the rest. Marked recurrences of the disease occurred in women who underwent pathological labor, artificial abortions, and exacerbations of chronic adnexitis.