SU1657190A1 - A method for preventing autoimmune orchitis after cryptoorchidism surgery - Google Patents

A method for preventing autoimmune orchitis after cryptoorchidism surgery Download PDF

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Publication number
SU1657190A1
SU1657190A1 SU894638557A SU4638557A SU1657190A1 SU 1657190 A1 SU1657190 A1 SU 1657190A1 SU 894638557 A SU894638557 A SU 894638557A SU 4638557 A SU4638557 A SU 4638557A SU 1657190 A1 SU1657190 A1 SU 1657190A1
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USSR - Soviet Union
Prior art keywords
orchitis
surgery
postoperative
cryptoorchidism
autoimmune orchitis
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SU894638557A
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Russian (ru)
Inventor
Андрей Иосифович Наконечный
Владимир Иосифович Гроховский
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Львовский государственный медицинский институт
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Abstract

Изобретение относитс  к медицине, в частности к урологии. Цель - повышение эффективности профилактики послеоперационных орхитов при лечении крипторхизма . Дл  этого в известный комплекс профилактики и лечени  послеоперационного орхита, включающий токоферол ацетат и никотиновую кислоту, дополнительно ввод т плацентарный полибиолин в возрастных дозировках, который назначают с первых суток после операции внутримышечно ежедневно . Способ позвол ет в 2-3 раза сократить разрешение инфильтрации тканей  ичка, предупредить развитие орхита и послеоперационную атрофию  ичек.The invention relates to medicine, in particular to urology. The goal is to increase the effectiveness of prevention of postoperative orchitis in the treatment of cryptorchidism. For this, placental polybioline is administered in age dosages, which is prescribed intramuscularly daily from the first day after the operation, into the well-known complex for the prevention and treatment of postoperative orchitis, including tocopherol acetate and nicotinic acid. The method makes it possible to reduce the resolution of the infiltration of the tissues of the testicle by a factor of 2-3, to prevent the development of orchitis and postoperative atrophy of the testis.

Description

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Изобретение относитс  к медицине, в частности к урологии.The invention relates to medicine, in particular to urology.

Цель изобретени  - повышение эффективности профилактики.The purpose of the invention is to increase the effectiveness of prevention.

Способ осуществл ют следующим образом .The method is carried out as follows.

После полного выхода больного из наркоза после орхипексии ему ввод т внутримышечно плацентарный полибиолин 1 раз в сутки в течение 6 дней по 0,3 г дет м от 6 мес цев до 10 лет, по О.Е г дет м старше 10 лет. Препарат раствор ют соответственно в 3 и 5 мл 0,5%-ного раствора новокаина или физиологического раствора. Одновременно ввод т токоферола ацетат и никотиновую кислоту.After the patient is completely out of anesthesia after orchippexy, he is given intramuscular placental polybioline 1 time per day for 6 days, 0.3 g of children from 6 months to 10 years, and according to O.E. children of more than 10 years. The drug is dissolved, respectively, in 3 and 5 ml of a 0.5% aqueous solution of novocaine or saline. Tocopherol acetate and nicotinic acid are added simultaneously.

Пример. Больной Ц.,5 лет 10 мес цев, поступил в клинику с диагнозом - правосторонний крипторхизм, пахова  форма. Произведена операци  - орхипекси  по методу Петривальского-Шемахера. С первых сутокExample. Patient C., 5 years and 10 months, was admitted to the hospital with a diagnosis of right-sided cryptorchidism, inguinal form. The operation was done - Orhipeksi method Petrivalsky-Shemakher. From the first day

после операции больному вводили ежедневно плацентарный полибиолин внутримышечно по 0,3 г в течение 6 дней, а также токоферол ацетат по 10 мг в сутки и никотиновую кислоту 0,5 мг/кг массы тела в 2-3 приема. Отмечено раннее разрешение инфильтрации тканей  ичка. При обследовании вы влено увеличение уровн  Т-супрессоров при отсутствии повышени  титра антител, а также торможени  миграции лейкоцитов к тестикул рному антигену. При контрольном обследовании через год -  ички свободно расположены в мошонке, тугоэластичной консистенциии, равны по величине, размеры соответствуют возрасту ребенка.after surgery, the patient was administered daily placental polybioline intramuscularly at 0.3 g for 6 days, as well as tocopherol acetate at 10 mg per day and nicotinic acid 0.5 mg / kg body weight in 2-3 doses. Early resolution of infiltration of ichka tissues is noted. The examination revealed an increase in the level of T-suppressors in the absence of an increase in antibody titer, as well as inhibition of leukocyte migration to a testicular antigen. During follow-up examination after one year, the eggs are freely located in the scrotum, of a tight elastic texture, equal in size, the dimensions correspond to the age of the child.

Предлагаемым способом проведена, профилактика орхита у 62 детей с различными формами одно- и двустороннего крипторхизма . Отмечено сокращение в 2-3 раза сроков разрешени  клеточной инфильтрась елThe proposed method carried out, prevention of orchitis in 62 children with various forms of single and bilateral cryptorchidism. A reduction by a factor of 2-3 in the resolution of cell infiltration was observed

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ции ткани  ичка в сравнении с использованием известного способа. Ни в одном случае не развилс  аутоиммунный орхит.tion of the tissue of the egg in comparison with the known method In no case did autoimmune orchitis develop.

Следовательно, способ  вл етс  высокоэффективным в предупреждении аутоим- мунного орхита, а соответственно послеоперационной атрофии  ичек, Способ прост в исполнении, лишен побочных эффектов , может быть широко внедрен в клинической практике.Consequently, the method is highly effective in preventing autoimmune orchitis, and, accordingly, postoperative atrophy of the cheek, The method is simple in execution, devoid of side effects, and can be widely implemented in clinical practice.

Claims (1)

Формула изобретени  Спороб профилактики аутоиммунного орхита после оперативного лечени  крип- торхизма, включающий введение токоферола ацетата и никотиновой кислоты в послеоперационном периоде, отличающийс  тем, что, с целью повышени  эффективности профилактики, ввод т плацентарный полибиолин с первых суток после операции в возрастной дозировке.Claims of the invention Sporob prophylaxis of autoimmune orchitis after surgical treatment of cryptochism, including the administration of tocopherol acetate and nicotinic acid in the postoperative period, characterized in that, in order to increase the effectiveness of prophylaxis, placental polybioline is administered from the first day after surgery at the age dosage.
SU894638557A 1989-01-16 1989-01-16 A method for preventing autoimmune orchitis after cryptoorchidism surgery SU1657190A1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040187A (en) * 1994-03-18 2000-03-21 Ivan Nikolaevich Golovistikov Method of determining the suppressor cell component of human immune status and a means for the realization thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Терещенко А.В. Профилактика осложнений оперативной коррекции крипторхизма у детей. Информационное письмо. Киевский НИИ урологии. - Киев, 1987. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040187A (en) * 1994-03-18 2000-03-21 Ivan Nikolaevich Golovistikov Method of determining the suppressor cell component of human immune status and a means for the realization thereof

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