SU1635982A1 - Device for intraocular lens confinement during their treatment with light - Google Patents

Abstract

The invention relates to medicine, more specifically to ophthalmology, to develop ways to increase the effectiveness of cataract treatment and to improve the quality of photochemical staining of intraocular lenses and prevent degradation of the polymeric lens material during processing. The device comprises a housing 1 and a cassette-type attachment 5 for fastening lenses, while the housing is sealed, has openings 2 and 3 for a blowing agent — nitrogen. Attachment 5 is made in the form of a plate with openings whose diameter is smaller than the diameter of the attachment zone of the supporting elements 3 or less.

Description

Fig 1

The invention relates to medicine, ophthalmology, and can be used in the surgical treatment of cataracts.

The purpose of the invention is to prevent degradation of the polymeric lens material.

Figure 1 shows a device, a general view in two projections; figure 2 - installation of IOL in the plate of the device; on fig.Z - heat filter.

The device consists of a sealed frame case 1 having openings 2 and 3 for inlet and outlet of a blowing agent (nitrogen). The front panel of the housing, on the side of irradiation with UV light, is equipped with a quartz plate 4. In the case 1, a board 5 with holes (21 pcs.) Of a cassette type is inserted, acting as an IOL holder, which are pressed to the back openings of the board with glass for 6 seconds. by means of spring latches 7 fixed by screws 8. The diameter of the holes is chosen in such a way as to remove the fastening elements of the lenses from the optical zone of the transmitted UV light. Such precaution is caused by the need to prevent the photodestruction of polypropylene (the material from which IOL fasteners are usually made), which is extremely sensitive to the action of UV light. The housing 1 is installed in a vertical position with the help of the rack 9, to which the housing 1 is fixed with rivets 10 (not shown). During irradiation, a heat filter 11 is installed between the device and the light source with water cooling through the inlet 12, the optical surfaces 13 of which are made of quartz glass that transmits UV light.

The device is used as follows.

The IOL from PMMA is removed from the original packaging and carefully placed in the holes of the armor holder 5 IOL of a cassette type device located 50 cm away from a mercury lamp (LED 120 A) emitting near UV light. The IOL is pressed against the board from the back of the housing with glass 6. It is verified that the IOL fasteners are not in the area of the optical path emitted by the light source. Through inlet 2, IOL purging with nitrogen is started. Simultaneously, a heat filter with water cooling is activated. Then a UV light source is prepared for operation. The test samples in dry form are exposed to near-UV light at room temperature. The following treatment mode is used: the total radiation flux is 50-100 W / m2.

Spectral analysis of materials Vis PMMA.

Absorption and Transmission Characteristics of Intact and Neighborhood Treated

The UV light of a PMMA IOL is determined by recording the corresponding spectra in the range from 190 to 500 nm on a spectrophotometer (Specord M-40, GDR, Carl Cess). The spectral characteristics of the PMMA IOL are compared before irradiation, as well as after treatment with near UV light. The measurement conditions for the spectra are similar in both cases.

Photodestruction of materials is assessed by registering Raman spectra of an IOL from PMMA on a DFS-24 laser spectrometer with an excitation line 5145. And with a light beam power of 200–350 mW, an interference filter is used, the linear width of the slit is 300 µm. scanning speed of 0.360 nm / min; samples in the illuminator are arranged according to their shape. The spectra are recorded with good reproducibility, and no significant changes were observed in the intensities and frequencies of the scattering lines in the spectra of samples that have undergone laser action for 4 hours.

Raman spectra in the spectral region of 1640 cm - in the region of frequencies of stretching vibrations of SS oscillations. The low-intensity vibration SS line in the Raman spectrum of the original PMMA IOL, and in the Raman spectrum

An IOL treated for 100 hours with UV radiation is clearly visible due to an increase in its integrated intensity. Along with the fact of increasing the intensity of the SS line of oscillations in the spectrum of the irradiated

Sample should be noted the appearance of a weak background fluorescence with the development of yellowish color of the material. The resulting changes in the Raman spectra are in good agreement with. photodestruction scheme

PMMA according to the equation

CH, CH n

"G" H

sn-s-

soots,

Have

COOCW-j

sc, cn-not with

sososi

" about

sn,

with I

sooo

from which it follows that the accumulation level of PMMA endgroups containing SS

double bonds (the right-hand fragment in the diagram) recorded on the Raman spectra of PMMA can serve as an objective criterion for the photodegradation of an IOL polymer material. The proposed device prevents degradation of the IOL polymer material during processing and protects IOL fasteners from light damage, and also increases the quality of photochemical IOL staining: greater depth of light yellow IOL staining (filtration of UV light) can be achieved . In addition, it is possible to impart to a large number of IOLs (21 pcs during one period of irradiation) a constant property to absorb light from the long-wave ultraviolet and short-wave visible spectral regions, i.e. the approximation of the spectral characteristics of the IOL to those of the natural lens of a young man. This feature provides a device for fixing the lenses.

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five

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It is possible to reduce the potential toxicity of UV absorbing IOLs prior to their implantation in the eye and the likelihood of the formation of ingredients in the IOL polymeric material capable of inducing toxic reactions to the eye, as well as the possibility of preventing damage to the optical surface of the IOL.

Claims (1)

An apparatus for retaining intraocular lenses during their light treatment, comprising a housing with a lens attachment device installed therein, characterized in that, in order to prevent degradation of the lens’s polymeric material, the housing is sealed and has openings for blowing in and out agent, while the front panel of the case is made of quartz glass, and the device for attaching the lenses is in the form of a plate with openings whose diameter is less than the diameter of the attachment zone of the supporting elements in the intraocular lenses. m radiation Fig.Ј I / 3