SU1599829A1 - Method of producing polymeric hydrogels - Google Patents

Method of producing polymeric hydrogels Download PDF

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Publication number
SU1599829A1
SU1599829A1 SU874282506A SU4282506A SU1599829A1 SU 1599829 A1 SU1599829 A1 SU 1599829A1 SU 874282506 A SU874282506 A SU 874282506A SU 4282506 A SU4282506 A SU 4282506A SU 1599829 A1 SU1599829 A1 SU 1599829A1
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USSR - Soviet Union
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dmso
water
polymeric
soluble
permeability
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SU874282506A
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Russian (ru)
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Олег Владимирович Суберляк
Владимир Иосифович Скорохода
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Львовский политехнический институт им.Ленинского комсомола
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Priority to SU874282506A priority Critical patent/SU1599829A1/en
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Abstract

Изобретение относитс  к химии полимеров и позвол ет получить полимерные гидрогели с повышенной водопроницаемостью - коэффициент водопроницаемости (53-79).10-4 м3.м-2.ч-1, что достигаетс  радикальной сополимеризацией смеси состава, мас.ч.: оксиалкилметакрилат 80This invention relates to the chemistry of polymers and makes it possible to obtain polymer hydrogels with a high permeability, a coefficient of permeability (53-79) . 10 -4 m 3. m -2. h -1 , which is achieved by radical copolymerization of a mixture of the composition, parts by weight: hydroxyalkyl methacrylate 80

поливинилпирролидон мол.м. 11000±2000 20polyvinylpyrrolidone mol.m. 11000 ± 2000 20

инициатор полимеризации 0,2polymerization initiator 0,2

водорастворимый донорно-акцепторный агент 1-40water-soluble donor-acceptor agent 1-40

вода 60-99, и использованием в качестве водорастворимого донорно-акцепторного агента вещества, выбранного из группы, состо щей из диметилсульфоксида, N-метилпирролидона, ацетонитрила. 1 табл.water 60-99, and using a substance selected from the group consisting of dimethyl sulfoxide, N-methylpyrrolidone, acetonitrile as a water-soluble donor-acceptor agent. 1 tab.

Description

Изобретение относитс  к химии и технологии полимеров, а именно к способу получени  полимерных гидрогелей , и может быть использовано в биологической и медицинской технике дл  создани  гидрогелевых сорбентов и устройств.The invention relates to polymer chemistry and technology, in particular, to a method for producing polymer hydrogels, and can be used in biological and medical technology to create hydrogel sorbents and devices.

Целью изобретени   вл етс  повышение водопроницаемости полимерных гидрогелей при сохранении их свето- прозрачности и прочности.The aim of the invention is to increase the permeability of polymeric hydrogels while maintaining their light transparency and strength.

Способ осуществл ют следующим образом.The method is carried out as follows.

Пример 1. 30 мае.ч. оксиэтил- метакрилата ОЭМ), 20 мае.ч. поли- И-винилпирролидона с мол.м. 11000± t 2000 (ПВП) и 0,2 мае.ч. персульфата кали  (ПС) раствор ют в 99 мае.ч. воды, добавл ют к смеси 1 мае.ч. диметилсульфоксида (ДМСО) и полимери- зуют смесь до образовани  гел  межцу двум  стекл нными пластинами с толщиной зазора:О,4 мм. Полученный в ви- де пленки гидрогель имеет характеристики , приведенные в таблице.Example 1. 30 ma.ch. hydroxyethyl methacrylate OEM), 20 ma.ch. poly-And-vinylpyrrolidone with mol.m. 11000 ± t 2000 (PVP) and 0.2 mach. Potassium persulfate (PS) is dissolved in 99 mash. water, is added to the mixture of 1 wt. dimethyl sulfoxide (DMSO) and polymerize the mixture before gel formation between the two glass plates with a gap thickness of about 4 mm. The hydrogel obtained as a film has the characteristics shown in the table.

Claims (1)

Формула изобретени Invention Formula Способ получени  полимерных гидрогелей путем радикальной сополимери- зацни в водном растворе оксиалкилме- такрилата, поливинилпирролидона и добавки, отличающийс  тем, что, с целью повьппени  водопроницаемости полимерных подрогелей при сохранении светопрозрачности и проч- НО.СТИ, в качестве добавки испольтуют водорастворимый донорно-акцепторньш агент, выбранный из группы, состо щей из диметилсульфоксида, N-метилпирролидона и ацетонитрнла, и процесс провод т при следующем соотношении компонентов, мае.ч.: .Оксиалкил- The method of obtaining polymeric hydrogels by radical copolymerization in an aqueous solution of hydroxyalkyl methacrylate, polyvinylpyrrolidone and an additive, characterized in that, in order to improve the permeability of the polymeric undergill while maintaining translucency and strength, the use of a water-soluble fiber was used as a supplement, a water-soluble glass, and a translucency and H. Baconium were used to make the water permeability of the polymeric drogells while maintaining translucency and strength. selected from the group consisting of dimethyl sulfoxide, N-methylpyrrolidone and acetonitrnl, and the process is carried out in the following ratio of components, wt.h.: Oxyalkyl- Метакрилат 80Methacrylate 80 Поливинилпирролидон .20Polyvinylpyrrolidone .20 Инициатор полимеризации Водорастворимый донорно- акцепторныйPolymerization initiator Water-soluble donor-acceptor агентagent ВодаWater Свойства полимерных гидрогелевых пленокProperties of polymer hydrogel films огласно-изобретениюaccording to the invention 1(ДМСО) 10(ДМСО) 20(ДМСО) 30 (ДМСО). 40(ДМСО) 10(ДМСО) 60(ДМСО) 20(МП) 20(ДМСО) 20(ДМСО) 30(АН) 10(АН)1 (DMSO) 10 (DMSO) 20 (DMSO) 30 (DMSO). 40 (DMSO) 10 (DMSO) 60 (DMSO) 20 (MP) 20 (DMSO) 20 (DMSO) 30 (AN) 10 (AN) 25 31 4t 52 65 22 67 39 38 44 71 4225 31 4t 52 65 22 67 39 38 44 71 42 сравнени compare 5050 2929 2020 2424 ГельGel - - - - Примечание. М. - молекул рна  масса межузлового фрагмента полимерной сетки. В примерах 1-8,11,12,13-19 в качестве оксиалкилметакрилата (ОАМА) использован 2-оксиэтилметакрШ1ат, в примере 9 - 2-оксипропш1метакрШ1ат, в примере 10 - 2-оксипропилакрнлат. МП - Ы-метш1пнрролндон. АН - ацетонитрнл. БК - бензойна  кислота.Note. M is the molecular mass of the interstitial fragment of the polymer network. In examples 1-8, 11, 12, 13-19, 2-hydroxyethylmethacrylate was used as hydroxyalkyl methacrylate (OAMA), in example 9, 2-hydroxypropshylmethacrylate, in example 10, 2-hydroxypropylacrylate. MP - N-metsh1pnrrnolddon. AN - acetonitrnl. BK is benzoic acid. ПЭИЗ - полиэтиленгликолевый эфир нзооктилфенола. ВА - винилацетат...PEIZ is nzooctylphenol polyethylene glycol ether. VA - vinyl acetate ... 95 95 95 95 9595 95 95 95 95 96 96 94 97 9796 96 94 97 97 0,40 0,41 0,41 0,42 0,420.40 0.41 0.41 0.42 0.42 0,4.0 0,43 0,40 0,41 0,420.4.0 0.43 0.40 0.41 0.42 53 57 63 70 76 36 77 59 57 70 79 6453 57 63 70 76 36 77 59 57 70 79 64 105 105 106105 105 106 0606 940,22 102940.22 102 950,32 68950.32 68 960,46 30 95 0,40 52960.46 30 95 0.40 52 неоднороден и непрозрачен 74 0,10heterogeneous and opaque 74 0.10
SU874282506A 1987-05-28 1987-05-28 Method of producing polymeric hydrogels SU1599829A1 (en)

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SU874282506A SU1599829A1 (en) 1987-05-28 1987-05-28 Method of producing polymeric hydrogels

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SU874282506A SU1599829A1 (en) 1987-05-28 1987-05-28 Method of producing polymeric hydrogels

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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент US № 3503942, кл. 260-80.75, опублик. 1970. За вка JP № 54-72291, кл. С 08 F 15/40, опублик. 1977. *

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