SU1595521A1 - Method of treating parodontium of oral cavity mucous membrane - Google Patents

Abstract

The invention relates to medicine, namely to dentistry. The aim of the invention is to reduce the duration of treatment. The goal is achieved by imparting to the lesion a mixture containing macrodiisocyanate, a polymerization accelerator dimethylaminomethylphenol in a 10: 1 ratio, and a medicinal substance trypsin, termitiline, furazolidone, gentamicin and sodium mefenaminate at the rate of 1 g of carrier, pre-hardening, and in the wake of the hardening, and in the course of time, in the room, and in the course of time, in the room, and in the course of time, in the room, and in the course of time, in the room, and in the course of time, in the room, and in the course of time, in the room, and in the course of time, in the room, and in the room, in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room, and in the room for the time to apply. in the form of a film. A positive effect is evaluated by an improvement in functional results.

Description

The invention relates to medicine, namely to dentistry, and is intended for use in the complex treatment of inflammatory and destructive diseases of the oral mucosa and periodontal disease.

The aim of the invention is to reduce the duration of treatment.

The method is carried out as follows.

After treatment of the oral cavity with an antiseptic solution (potassium permanganate, furatsilina, tsetral, etoni) and isolation of the affected area from a large amount of saliva, a previously prepared therapeutic polyurethane material is applied. The latter is prepared in the form of a soft drug-adhesive composition and 8 as an active adhesive

films that are applied with regard to the localization of the affected area.

A soft drug-adhesive composition is obtained after adding a medicinal substance to the ampoule with an adhesive base at the rate of administration per gram of carrier. The contents are well mixed and stored in a sealed ampoule at a temperature appropriate to the technical conditions. Before use, the adhesive composition is mixed with a spatula on a dry, smooth surface of a glass slide, for which the required amount of bioactive macrodisocyanate and polymerization accelerator is applied. When it appears in the mass of the first vesicles (the beginning of foaming), it is applied to the pathological focus.

next sl

To prepare a therapeutic polyurethane film 1 / g, the glue base is poured onto a dry glass substrate, the preparation is applied, mixed well and combined with a polymerization accelerator. Using a glass roller, roll the mass on the substrate in a thin layer and leave until full polymerization at room temperature. One day later, the film is removed. It is thin (0.2-0.3 mm), durable, highly elastic, porous

film.

The bioactive film can be recommended for multiple application to the pathological focus in the area of pronounced mobility of soft tissues (gy. Fixation to the moist mucous membrane) (the shell is provided by adhesion. The patient reapplies the film after taking it from the mucosa before eating. After thorough washing with water, it is suitable for reapplication. In some cases, an additional active polyurethane film can be fixed with the same type of soft drug-adhesive composition d.

Soft Drug Adhesive} The composition is used to apply to the pathological lesion in places of sedentary mucosa. It has better fixation due to adhesion to the mucous membrane and is maintained from several hours to 4-5 days, depending on the localization of the pathological focus and the behavior of the patient.

Example. 1. Ill S-va T., 49 years old. Complaints of pain and a feeling of roughness on the mucous membrane of the cheeks, especially on the left. Roughness of the mucous noticed a year ago. - I did not go to the doctor. The pain appeared two weeks ago while taking hard and spicy food.

Objectively; in the distal cheeks, on a slightly edematous and hyperemic background of the mucous membrane, there are multiple single and fused papules. In the area of projection 5-6 teeth, two zozy surfaces of 0.3 x 0.5 cm are defined.

Diag oz: lichen planus, erosive shape.

Treatment: irrigation of the oral solution-. rum etony, a bio-film with sodium mefenaminate (10 mg / g Carrier) is applied to the erosive surface.

The next day, the patient's condition improved, the pain decreased as biofilm was applied, food intake did not cause pain. After repeated application of biofilm for 2 days, pronounced epithelization of erosive surfaces from the periphery, a decrease in hyperemia, was observed. Full maturation occurred after 3 treatments.

Example 2. Patient M-Ko V.V., 21 years old. Complaints of indisposition, temperature 37.2 ° C, the presence of sharply painful ulcers on the gums of the upper and lower jaws to the left in the distal part, pain in the mouth of the mouth, and unpleasant smell from the mouth. Sick during the week.

Objectively: pronounced, hyperemia and swelling of the gums of the upper and lower jaws on the left are spread; the gingival papillae, marginal edge of the gum and mucous cheek in the area of 5678 teeth are removed, covered with gray bloom, bleeding when touched.

0Diagnosis: acute necrotizing gingivostomatitis, moderately severe.

Treatment; under the bath from the solution of potassium-and-calcium potassium, toothpaste and soft plaque and plaque are removed from the ulnar surfaces. A glue-treatment composition with terilitin (400 PE in 1 g of carrier) was applied to the area of the ulcer.

The next day, the condition improved, the temperature returned to normal, there were no complaints about the painfulness of the jugular surfaces. Ulcerative surfaces clean from napet, decreased swelling. After applying 35 therapeutic adhesive compositions with gentamicin (25 mg / g of carrier), epithelialization of ulcer surfaces was observed for 1 day, the area and intensity of mucosal hyperemia significantly decreased, 40 Overlaying of the therapeutic adhesive composition with sodium mefenaminate (10 mg / g of carrier ) contributes to the complete subscription of the inflammatory process.

Being a drug depot, the bioactive polyurethane film at the same time is a good protection of the pathological focus against external irritants, which in turn also reduces the treatment time. The method helps to improve the functional results.

Claims (1)

The invention The method of treating periodontal diseases of the oral mucosa by administering drugs immobilized on a polymer base, characterized in that, in order to shorten the treatment time, a mixture containing macrodiisocyanate, a polymerization accelerator, is applied to the lesion 515955216. xDimmythylaminomethylfenl in the ratio of sodium phenaminate based on 1 g of the carrier 10; 1 and medicinal substance - trypsin, l, with pre-hardening and forformorlitin, furaeolidone, gentamicin and its emulsion in the form of a film.