SU1584349A1 - 2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action - Google Patents

2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action

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Publication number
SU1584349A1
SU1584349A1 SU4656018/04A SU4656018A SU1584349A1 SU 1584349 A1 SU1584349 A1 SU 1584349A1 SU 4656018/04 A SU4656018/04 A SU 4656018/04A SU 4656018 A SU4656018 A SU 4656018A SU 1584349 A1 SU1584349 A1 SU 1584349A1
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SU
USSR - Soviet Union
Prior art keywords
cardiostimulating
oxo
action
compound
dihydropyridazynyl
Prior art date
Application number
SU4656018/04A
Other languages
Russian (ru)
Inventor
Ю.М. Ютилов
И.В. Комиссаров
Н.Н. Смоляр
И.Т. Филиппов
И.М. Самойлович
Original Assignee
Институт физико-органической химии и углехимии АН УССР
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Priority to SU4656018/04A priority Critical patent/SU1584349A1/en
Application granted granted Critical
Publication of SU1584349A1 publication Critical patent/SU1584349A1/en

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Abstract

FIELD: production of heterogeneous compounds; medicine. SUBSTANCE: synthesis is carried out by reaction of ortho-phenylydene diamine with 3'-oxo-4', 5'-dihydropyridazine-6'-carboxylic acid, the process takes place by heating in solution of orthophosphoric acid. Yield of compound having essential formula CHNO is 96 %, its melting point, 206-209 C. Toxicity of desired compound LDis 400 mg/kg. At 4.7 10mmol/l concentration of novel compound amplitude of cardiac muscle contraction is increased by 35 %. EFFECT: more effective compound with hypotensive and cardiostimulating action. 1 tbl
SU4656018/04A 1988-11-30 1988-11-30 2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action SU1584349A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4656018/04A SU1584349A1 (en) 1988-11-30 1988-11-30 2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4656018/04A SU1584349A1 (en) 1988-11-30 1988-11-30 2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action

Publications (1)

Publication Number Publication Date
SU1584349A1 true SU1584349A1 (en) 1997-12-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU4656018/04A SU1584349A1 (en) 1988-11-30 1988-11-30 2-(3′-oxo-4′,5′-dihydropyridazynyl-6′)-benzimidazole possessing hypotensive and cardiostimulating action

Country Status (1)

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SU (1) SU1584349A1 (en)

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