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Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Abstract
FIELD: medicine. SUBSTANCE: synthesis is carried out by reaction 2-(fluorophenyl)-DL-alanine with 4-[bis-(2- chloroethyl)-amino] -phenylacetylchloride in the presence of sodium hydroxide. The process takes place in the medium of aqueous dioxane at temperature (-5)- (-20) C. Desired product has empirical formula CHClFNO, its yield is 56.4% , its melting point is 129-131 C. EFFECT: produces novel compound having improved efficiency. 2 tbl
SU4475322/04A1988-08-181988-08-18N-{4-[bis-(2- chloroethyl)- amino]- phenylacetyl} -2-(4-fluorophenyl)-dl-alanine having antitumoral effect
SU1568480A1
(en)