SU1563187A1 - 1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
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1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
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FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: product: 1-(2-ethoxyethyl)-4-hydroxypiperidine. Synthesis of new compound is carried out by reaction of 1-(2-ethoxyethyl)-4-ketopiperidine with sodium borohydride in isopropanol. Yield is 99.9%, $$$ = 0.18; empirical formula is $$$. Substances synthesized on the base of new compound show local anesthetic activity comparable with that of novocaine. EFFECT: synthesis of new compound indicated above.
SU4445654/04A1988-06-221988-06-221-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
SU1563187A1
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1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
1-(2-ethoxyethyl)-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-acylhydroxypiperidine hydrochlorides showing local anesthetic activity
1-(2-ethoxyethyl)-4-ethynyl-4-hydroxypiperidine as an intermediate compound for synthesis of 1-(2-ethoxyethyl)-4-ethynyl-4-acyloxypiperidine hydrochlorides showing local anesthetic activity
1-(3-butoxy propyl) -4-oxopiperidine as intermediate compound in synthesis of 1-(3-butoxy propyl) -4-phenyl-4-propionyloxypiperidine hydrochloride having analgesic activity