SU1681502A1 - 3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects - Google Patents

3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects

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Publication number
SU1681502A1
SU1681502A1 SU4744306/04A SU4744306A SU1681502A1 SU 1681502 A1 SU1681502 A1 SU 1681502A1 SU 4744306/04 A SU4744306/04 A SU 4744306/04A SU 4744306 A SU4744306 A SU 4744306A SU 1681502 A1 SU1681502 A1 SU 1681502A1
Authority
SU
USSR - Soviet Union
Prior art keywords
dimethoxybenzoyl
bromobenzofuran
dimethylaminomethyl
hydroxy
antiarrythmic
Prior art date
Application number
SU4744306/04A
Other languages
Russian (ru)
Inventor
Т.И. Муханова
А.А. Столярчук
Г.И. Степанюк
О.С. Медведев
С.Ф. Дугин
Original Assignee
Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе
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Application filed by Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе filed Critical Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе
Priority to SU4744306/04A priority Critical patent/SU1681502A1/en
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Publication of SU1681502A1 publication Critical patent/SU1681502A1/en

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Abstract

FIELD: organic chemistry. SUBSTANCE: product: heterocyclic compound, 3-(2,5-dimethoxybenzoyl)-4-dimethylaminomethyl-5-hydroxy-6-bromobenzofuran hydrochloride. Synthesis is carried out by bromination of 3-(2,5-dimethoxybenzoyl)-5-hydroxybenzofuran following by aminomethylation of bromo-derivative prepared. EFFECT: improved method of synthesis. 14 tbl
SU4744306/04A 1989-07-26 1989-07-26 3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects SU1681502A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4744306/04A SU1681502A1 (en) 1989-07-26 1989-07-26 3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4744306/04A SU1681502A1 (en) 1989-07-26 1989-07-26 3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects

Publications (1)

Publication Number Publication Date
SU1681502A1 true SU1681502A1 (en) 1994-06-15

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Application Number Title Priority Date Filing Date
SU4744306/04A SU1681502A1 (en) 1989-07-26 1989-07-26 3-(2, 5-dimethoxybenzoyl)-4-dimethylaminomethyl-5- hydroxy-6-bromobenzofuran hydrochloride showing analgetic, local anesthetic, anticonvulsant, antiarrythmic, stimulating coronary, cerebral and renal blood circulation effects

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SU (1) SU1681502A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696365B2 (en) 2003-08-01 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
US7723366B2 (en) 2001-02-20 2010-05-25 Chugai Seiyaku Kabushiki Kaisha Azole compounds as malonyl-CoA decarboxylase inhibitors for treating metabolic diseases
US7786145B2 (en) 2003-08-01 2010-08-31 Chugai Seiyaku Kabushiki Kaisha Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
US8080665B2 (en) 2003-08-01 2011-12-20 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
US7723366B2 (en) 2001-02-20 2010-05-25 Chugai Seiyaku Kabushiki Kaisha Azole compounds as malonyl-CoA decarboxylase inhibitors for treating metabolic diseases
US8110686B2 (en) 2001-02-20 2012-02-07 Chugai Seiyaki Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
US7696365B2 (en) 2003-08-01 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors
US7786145B2 (en) 2003-08-01 2010-08-31 Chugai Seiyaku Kabushiki Kaisha Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
US8080665B2 (en) 2003-08-01 2011-12-20 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors

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