SU1547277A1 - 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity - Google Patents

1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity

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Publication number
SU1547277A1
SU1547277A1 SU4482657/04A SU4482657A SU1547277A1 SU 1547277 A1 SU1547277 A1 SU 1547277A1 SU 4482657/04 A SU4482657/04 A SU 4482657/04A SU 4482657 A SU4482657 A SU 4482657A SU 1547277 A1 SU1547277 A1 SU 1547277A1
Authority
SU
USSR - Soviet Union
Prior art keywords
quinazolinedione
diglycidyl
antitumor activity
showing antitumor
synthesized
Prior art date
Application number
SU4482657/04A
Other languages
Russian (ru)
Inventor
Г.А. Лосев
Н.И. Коротких
В.А. Чернов
О.П. Швайка
Original Assignee
Институт физико-органической химии и углехимии АН УССР
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт физико-органической химии и углехимии АН УССР filed Critical Институт физико-органической химии и углехимии АН УССР
Priority to SU4482657/04A priority Critical patent/SU1547277A1/en
Application granted granted Critical
Publication of SU1547277A1 publication Critical patent/SU1547277A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

FIELD: heterocyclic compounds. SUBSTANCE: product: 1,3-diglycidyl-2,4-quinazolinedione. Synthesis is carried out from urea and anthranilic acid. 2,4-Quinazolinedione synthesized at the first stage is subjected for interaction with epichlorohydrin and condensation products were dehydrochlorinated with alkali. The yield is 58-82%; LD= 280 mg/kg. Synthesized compound shows antitumor activity. EFFECT: increased yield. 3 tbl
SU4482657/04A 1988-07-01 1988-07-01 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity SU1547277A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4482657/04A SU1547277A1 (en) 1988-07-01 1988-07-01 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4482657/04A SU1547277A1 (en) 1988-07-01 1988-07-01 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity

Publications (1)

Publication Number Publication Date
SU1547277A1 true SU1547277A1 (en) 1997-07-20

Family

ID=60517759

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4482657/04A SU1547277A1 (en) 1988-07-01 1988-07-01 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity

Country Status (1)

Country Link
SU (1) SU1547277A1 (en)

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