SU1334658A1 - Method of synthesis of m-chlorodiphenylmethylurea - Google Patents
Method of synthesis of m-chlorodiphenylmethylureaInfo
- Publication number
- SU1334658A1 SU1334658A1 SU3929189/04A SU3929189A SU1334658A1 SU 1334658 A1 SU1334658 A1 SU 1334658A1 SU 3929189/04 A SU3929189/04 A SU 3929189/04A SU 3929189 A SU3929189 A SU 3929189A SU 1334658 A1 SU1334658 A1 SU 1334658A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- urea
- synthesis
- chlorodiphenylmethylformamide
- hcl
- yield
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
FIELD: organic chemistry, substituted derivatives of urea. SUBSTANCE: synthesis is carried out from m-chlorodiphenylmethylformamide which is treated with urea taken as an aqueous solution in the presence of HCl at 135-140 C in isopropanol medium at the molar ratio m-chlorodiphenylmethylformamide-HCl-urea 1:(1.5-3.5):(5-6). Under these conditions the yield is increased from 70% (by known method) to 89.7% Synthesized compound is used in medicine as antiarrhythmic and anticonvulsant agent. EFFECT: increased yield of the end product. 1 tbl
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU3929189/04A SU1334658A1 (en) | 1985-07-12 | 1985-07-12 | Method of synthesis of m-chlorodiphenylmethylurea |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU3929189/04A SU1334658A1 (en) | 1985-07-12 | 1985-07-12 | Method of synthesis of m-chlorodiphenylmethylurea |
Publications (1)
Publication Number | Publication Date |
---|---|
SU1334658A1 true SU1334658A1 (en) | 1995-10-10 |
Family
ID=60543170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU3929189/04A SU1334658A1 (en) | 1985-07-12 | 1985-07-12 | Method of synthesis of m-chlorodiphenylmethylurea |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU1334658A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2569684C1 (en) * | 2014-12-29 | 2015-11-27 | Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский политехнический университет" | Method of obtaining meta-chlorobenzhydrylurea(halodif) with application of magnetic nanoparticles, modified with sulphogroups |
-
1985
- 1985-07-12 SU SU3929189/04A patent/SU1334658A1/en active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2569684C1 (en) * | 2014-12-29 | 2015-11-27 | Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский политехнический университет" | Method of obtaining meta-chlorobenzhydrylurea(halodif) with application of magnetic nanoparticles, modified with sulphogroups |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU9200823D0 (en) | Process for the production of cyclical carbamide derivatives and medical preparations containing them as active agents | |
EP0191335A3 (en) | Preparation process of (6r)-tetrahydro-l-biopterin | |
SI0754679T1 (en) | Process for the preparation of creatin or creatine-monohydrate | |
SU1334658A1 (en) | Method of synthesis of m-chlorodiphenylmethylurea | |
FR2581641B1 (en) | PROCESS FOR THE PREPARATION OF 6-ALKOXY (LOWER) -1-NAPHTOIC ACIDS AND CORRESPONDING ESTERS AND USE OF THIS PROCESS FOR THE PREPARATION OF 6-ALKOXY (LOWER) -5-HALO-1-NAPHTOIC ACIDS AND CORRESPONDING ESTERS | |
SU1407014A1 (en) | Oligoethyleneoxide sodium sulfonate as a modifying agent of polyethylene terephthalate and a method of its preparing | |
SU1589605A1 (en) | Method of synthesis of n,n' -diderivatives of 2(3)-guanidinoalkanethiols | |
SU1743148A1 (en) | Method of nitrilotriacetic acid synthesis | |
SU1401842A1 (en) | Method of synthesis of diphenylmethylureas | |
SU1363779A1 (en) | Method of synthesis of 2(3)-guanidoalkanethiols | |
SU1746665A1 (en) | N-acyl derivatives of 4-phenylpyrrolidine-2-ones showing cerebroprotective (nootropic) action | |
SU1538476A1 (en) | Method of benfothiamine synthesis | |
SU1824860A1 (en) | Method of polyfluoroethane synthesis | |
ATE14118T1 (en) | PROCESS FOR PREPARING N-METHOXY-N-METHYL-URETHANES. | |
SU1706174A3 (en) | N-substituted 5-phthalimidonaphthalene-1-sulfamides as semiproducts for synthesis of n-substituted aminonaphthalenesulfamides | |
SU1589606A1 (en) | Method of synthesis of n'-monoderivatives of 2(3)-guanidinoalkanethiols | |
SU1557962A1 (en) | Method of acetoacetic acid amide synthesis | |
SU1840597A1 (en) | Bis(chloroximino)acetone preparation method | |
SU1547277A1 (en) | 1,3-diglycidyl-2, 4-quinazolinedione showing antitumor activity | |
DE3663131D1 (en) | Process for the preparation of aqueous ammonium sulphocyanide solutions | |
SU1314641A1 (en) | METHOD OF SYNTHESIS OF DERIVATIVES OF 17α-HYDROXY-3-OXOANDROST-4-ENE-17b-CARBOXYLIC ACID | |
SU1840590A1 (en) | Method for preparing bis-(chlorooxyimino)-acetone | |
SU1367194A1 (en) | 1-adamantane carboxylic acid lithium salt showing psychostimulating activity | |
SU1743175A1 (en) | Diamides of o-[2-(4-phenoxyphenoxy)ethyl]thiophosphoric acid showing juvenile activity | |
SU1422601A1 (en) | Method of arylsulfonylisocyanate synthesis |