SU1402349A1 - Suturing material - Google Patents

Description

(21} 3410017 / 28- (22) 01.12.82 (46) 06/15/88. Bull. 22 (71) All-Union Scientific Research and Testing Institute of Medical Equipment (72) S.I. Belykh, A. B. Davydov , A.D. Moshchensky, N.N. Kanshin, I.L.Kovalenko, Yu.B. Kirillov, G.I. Osipov and R.I. Ut Myshev (53T 615.475 (088.8)

(56) Clinical Surgeons, 1978, No. 8, p. 71-75.

(54) SUCK MATERIAL

(57) The invention relates to medicine. Suture material is based on bioabsorbable polymers. A layer of a copolymer of H-vinylpyrrolidone and alkyl acrylate or methacrylate containing 20-50% N-vinylpyrrolidone with a biodegradation period shorter than the biodegradation period of the material and an antimicrobial preparation is applied to the thread. The ratio of components, May,%: copolymer of N-vinylpyrrolidone and alkyl acrylate or methacrylate 60-99; antimicrobial drug 1-40. The suture has a tensile strength 2-2.5 times higher than the known materials and a higher knot joint strength.

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ABOUT

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The invention relates to medical technology and relates to the manufacture of suture materials.

The aim of the invention is to increase the strength and control the prolongation of the action of the preparations.

The suture material is made on the basis of bioabsorbable polymers, and at this I a layer of copolymer K of vinylpyrrolidone and alkyl acrylate or methacrylate containing 20-50% N-vinylpyrrolidone with a biodegradation period and containing one or several antimicrobial preparations is applied to the thread the ratio of components, wt.%:

Copolymer K-vinyl pyrrolidone with alkyl acrylate 60-99

Antimicrobial

preparations1-40

EXAMPLE 1 A solution of a copolymer of butyl methacrylate with H-vinylpirrolidone containing 20% in ethanol (15 g of copolymer in 100 ml of alcohol) containing 6 g of dioxidine is applied onto a capron filament with a thick tex. The thread is dried. The thickness of the dioxidine-containing copolymer layer is 0.4 to. The specific strength of the yarn is 65 gf / tex, the specific strength of the knot joint is 58 gf / tex. The maximum duration of the drug detection. blood 18 days.

Example 2, A 48 tex thick polyvinyl alcohol filament was coated with a solution of methyl methacrylate copolymer with N-vinyl pyrrolidone (the content of p-vinyl pyrrolidone units, 35%) in ethyl alcohol (10 g copolymer in 100 ml of alcohol) containing

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14023492

threads. The specific strength of 74 gf / tex, the strength of a nodular compound is 53 gf / tex, the maximum term for detecting a drug in blood is 8 days,

EXAMPLE 4 Analogously to Example 3, a film was applied to the thread from a mixture (1: 1 ratio) of GSB-1 copolymer and vinylpyrrolidone copolymer with methyl methacrylate of the brand PPM- (28.6 May,% vinylpyrrolidone),

ExampleB As in Example 3, a film was applied to the thread from a mixture of SB-1 and P11M-1 copolymers at a ratio of 1: 4

P. pm. 6, Acid-treated yarn from capron No. 1 applied a film from an alcohol solution of PPB-1 copolymer containing a mixture of dioxidine and quinoxidin (the ratio of the components is alcohol 120 ml, copolymer 19 g of dioxidine 4.5 g, Quinoxin - Dina 4.5 g). Film thickness 0.27 of the thickness of the filament,.

The suture material has a tensile strength of 2-2.5 times higher than the strength of the known material and a higher strength of the knot-joint, which allows expanding the range of antimicrobial preparations used.

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Claims (1)

Formula Suture material based on bioabsorbable polymers, about tl, which is because, in order to increase the strength and control of the prolonged action of the preparation, a layer of N-vinylpyrrolidone and alkyl acrylate or methacrylate is applied to the thread. containing 20-50% K-vinylpyrrolidone with a biodegradation period less than the biodegradation period of 2 g of kanamycin. The thread is dried. The thickness of the material and one or several anti-copolymer layers of anti-starch containing its microbial preparations-, with the following kanamycin, is 0.1 filament thick. . The ratio of components, wt.%: For example, a solution of a copolymer of vinyl. Pyrrolidone and butyl methacrylate brand PPB-1 / containing gentamicin (the ratio of the components of the copolymer is 12 g, gentamicin 4 g, ethyl alcohol 100 ml) is applied to the acidic nylon 93.5 tex. The coating has a thickness of 0.28. Thickness 50 Copolymer I-Vinsh1pirrodido and alkyl acrylate or methacrylate Antimicrobial drugs 60-99 1-40 Formula Suture material based on bioabsorbable polymers, about tl, which is because, in order to increase the strength and control of the prolonged action of the preparation, a layer of N-vinylpyrrolidone and alkyl acrylate or methacrylate is applied to the thread. containing 20-50% K-vinylpyrrolidone with a biodest term Copolymer I-Vinsh1pirrodido and alkyl acrylate or methacrylate Antimicrobial drugs 60-99 1-40