SU1393476A1 - Multichannel pipette - Google Patents

Abstract

The invention relates to medical technology, can be used in the dosing of small volumes of reagents and biofluids, and it allows to increase the accuracy of dosing by reducing deviations from a given dose emitted by each frequency generator. The pipette is equipped with C-shaped brackets, on one side rigidly connected with pistons, and on the other hand having adjustment screws, the carriage being made in C-section for engagement with the brackets on the side of adjustment screws, 4 or

Description

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The invention relates to medical technology and can be used in the dosing of small volumes of reagents and biofluids in clinical diagnostic laboratories of medical institutions, as well as in other areas of technology where it is necessary to simultaneously receive a certain number of doses and their volumes in accordance with the number of channels in the pipette and the establishment of the required volumes of doses for each of them.

The aim of the invention is to improve accuracy by reducing deviations from a given dose, issued by each cylinder.

FIG. 1 shows pre; 1 pipette, general view; in fig. 2 - rasare A-A in FIG. one; in fig. 3 — cylinder block with pistons and brackets; in fig. A - section BB in FIG. 3

The pipette contains a vertical body 1, the lower part of which has the shape of a box, a carriage 2 having a C-shaped profile in cross section, a block of 3 shchindrov containing all the cylinders of the pipette and fixed in the body 1 with screws 4. pistons 5, cylindrical ends of which are inserted into a block of 3 cylinders, and opposite ends fitted with fixed C-shaped brackets 6 with screws 7 regulating the strokes of each wall and locking screws 8 are inserted into the cavity of the channel of the carriage 2.

A handle 9 is screwed to the upper part of the housing 1 with a spring-loaded spring 10 placed in it along the axis of the housing 10 by a rod 11, the lower end of which is connected to the common carriage, and the upper one interacts with the pusher 12 through its platform A button 13 with a lock nut 14 and an employee for setting the value of the movement of the pushers, and therefore setting the value of the volumes of the dosing of all channels simultaneously. In the upper part of the handle 9 are located a knob 15 of the slider, which provides additional movement of the pistons for dropping the droplets remaining in the channels during dispensing, and a spring 16, which revolves the button of the slider to its original position. Access to the adjusting screws is secured with external devices and removable KpijiiiiKofi 17,

62

fixed in the case of a spring latch 18.

The replaceable element contains a piston 5, which is rigidly connected to the C-shaped brackets 6, in the upper part of which the adjusting screws 7 are screwed, and the stopper 1 and 8 screws. The ends of the pistons 5 are inserted into the cylinder block 3.

A multichannel pipette works as follows.

Before starting work, the required dose volume is established for all pipette channels simultaneously. This is achieved by adjusting the amount of movement of the pusher 12 by unscrewing or screwing the button 13 and then locking it with a lock nut 14 on the upper end of the pusher. Then the tips (not shown), clad on the conical ends of the cylinder block 3, are lowered into the metered liquid. Button 13 is pressed all the way to the full amount of movement of the pusher. When this is done, the spring-loaded spring 10 moves downward along the stem 11, together with the carriage 2 associated with it. All vehicles 5 carried by the carriage are displaced downward by the amount of movement of the pusher. When the button 13 is subsequently lowered in the block of 3 cylinders, a vacuum is created and the liquid flows into each of the tips in the required volume. exactly by setting the gap b (Fig. 2) by means of the adjusting screws 7 and fixing their position with the locking screws 8. At the same time, since the piston stroke is the difference between the amount of movement of the pusher and the gap b, the decrease or increase in the dose volume corresponds to or reduce the gap b. By pressing the buttons 15 and 13 successively, the liquid is pushed out of each channel of the pipette in precisely defined volumes.

In order to expand the dosing limits of the pipette, it is possible, at 17 in and without having to unscrew the screws 4 without the need of a tool, to replace the existing element with other removable elements designed for other dosing ranges.

The proposed design of a multichannel pipette, in comparison with the known one, allows us to provide ease of operation, which reaches P

With the possibility of 1, U-1-U1, UJ4 but each of Kaiia.riDF) and the installation of interchangeable elements. With such a gas phase, one rod is used for a wide dosing range and the possibility of dose adjustment for each channel is retained. A surge in each channel removes the stringent requirements imposed on the treatment of the plunger pipes and cylinders, which, in turn, leads to cheaper manufacturing of a multi-channel pipette. The design of the proposed pipette is simpler, which also leads to cheaper prices.

The pipette body is designed in such a way that a complete disassembly of the pipette is not needed to replace the elements. In addition, the pipette can be used on a different number of channels. With the ycT element of the replaceable element, it is possible to insert the necessary number of pistons from 1 to n, where n is the number of channels in the multichannel pipette.

The cylinder block is made by pressing and has the shape of a whole body, in which

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The torus has canapes. Iressovlnpe selected in the economy, since at least a cheap form of processing.

Formula

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A multichannel pipette, including the body, is installed in it with the possibility of reciprocating movement of the rod, cylinder block, located) in the lower) 1 part of the body, pistons installed in ras, and a carriage for moving the pistons, connected to the rod In order to increase accuracy by reducing deviations from a given dose delivered by each cylinder, the pipette is equipped with C-brackets on one side rigidly connected to the pistons and on the other side having adjustment screws. carriage is made & C-shaped section for engagement with brackets on the side of adjustment screws,

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with tl l 13 it spruce L. Dombrovska ednik O, Golovach Toxpeji, L. Serdyukova Corrector S.Shekmar

 19P6 / 8

Tirll) MBNII State Committee on the USSR Committee

for inventions and discoveries 113035, Mogkpd, Zh-35, Raushsk nab. d. 4/5

Signature

Claims (1)

Claim A multichannel pipette, including a body installed in it with the possibility of reciprocating movement of the rod, a cylinder block located in the lower part of the body, pistons installed in the cylinders, and a carriage for moving the pistons connected to the rod, which means that, in order to improve accuracy by reducing deviations from a given dose issued by each cylinder, the pipette is equipped with C-shaped brackets, on the one hand rigidly connected to the pistons and on the other hand having adjusting screws, and the carriage is made A cross-section C-shaped for engagement with brackets on the side of the adjusting screws. AA (pi / g. 2 1 393476 s-s of FIG. 4-