SU1380750A1 - Method of prophylaxis of recurrent lithogenesis in kidneys - Google Patents

Abstract

The invention relates to medicine, more specifically to urology. The purpose of the invention is to increase the effectiveness of prevention of re-stone formation in the kidneys and urinary tract by increasing urine proteolysis through enzyme therapy carried out every ten days. 1-decade - drugs that improve the function of the kidneys are introduced - phytopreparations. 2-decade — correction cycle associated with pH parameters (eg, acezine pepsin or p-normin). - agents that increase diuresis and improve renal circulation

Description

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This invention relates to medicine, namely, to urology.

The purpose of the invention is to increase the effectiveness of prevention of re-stone formation in the kidneys and urinary tract,

Example 1. Patient L., 58 years old, was admitted to the clinic with complaints of pain in the right side.

The examination revealed protei nuri, leukocyturia, a significant amount of urate in the urine. Initial urine proteolysis: urine acid 1.312, protein 0.638, proteolytic activity 1.530, inhibitors 20.45, proteolysis index 0.118.

Clinical diagnosis, uratokamenna disease, coral stone of the right kidney, chronic pyelonephritis.

The operation was performed - pyelolitomite, nefrostomp. The postoperative course without complications. At discharge from the hospital, the patient was advised on the prevention of education and her methodological assistance. Under the supervision of a urologist at the place of residence, the patient was systematically treated.

The podkadnoe treatment (10 days of each month) consisted of cycles: 1 decade — a functional cycle, preparations improving kidney function were injected, phytopreparations, 2 decade a correction cycle, rto pH 5.0–5.4, the patient took Acidineps M1, as well as additionally herbal remedies that increase diuresis, as well as all the preparations leading to an improvement in the renal circulation, the 3-decade - antibacterial cycle, were administered the preparations in accordance with the sensitivity of the powdered micro (1).

One year after the operation, no recurrence was observed. Urine proteolysis indicators: uric acid 0.920, protein 0.288, proteolytic activity 2.114, inhibitors 0.42, proteolysis index 17.31.

X-ray data showed an improvement in kidney function. Obsled. after 3 years - no recurrence. Proteolysis indicators: uric acid 0.920, protein 0.288, proteolytic activity 2.114, proteolysis inhibitors 0.83, index 8.844.

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Thus, the stone formation metaphilactics was successful.

Example 2. Patient F., 60 years old, was admitted to the hospital with a diagnosis of oxalate nephrolithiasis, a stone of the lower third of the right ureter.

Urine proteolysis: protein 1,100, proteolytic activity 0.336, inhibitors 3.21, proteolysis index 0.095.

Ureterolite extraction operation was performed on the right. The postoperative course without complications.

Prophylactic treatment in the future on an outpatient basis was carried out according to the decadal principle specified in Example 1.

In the corrective cycle, the patient received a panzinorm due to a pH of 6.3-6.5. The level of urine proteolysis was determined twice per month.

At follow-up after one year of recurrence, the disease was not revealed, the renal function was not impaired.

Urine proteolysis indicators: protein 0.242, proteolytic activity 1.312, protease inhibitors 2.77, proteolysis index 4.619.

Three years after the operation, on the background of the preventive therapy being carried out, the patient's condition is satisfactory, no complaints, no recurrence of the disease was detected. Correction of proteolysis and urine pH over a long period of time has been an effective means of preventing re-stone formation.

Clinical observation of 30 bolus nephrolithiasis, regularly accepted treatment using the proposed method, showed that relapse was detected in 1 patient (3.3%), in the control group relapses were 22% in patients who did not take prophylactic medication, and 20% in patients not including oral treatment with enzyme preparations.

Claims (1)

Invention Formula A method for the prevention of re-stone formation in the kidneys, including dietary and phytotherapy, the introduction of antibacterial drugs, and, Funds, corrective urine pH, of t-l, and that, with a price of 3,380,750 In order to increase the effectiveness of pro-proteolytic enzymes of pepsin-polactics, at urine pH less than 6.0, similar effect, and at pH 6.0, enzyme enzymes are more or less administered orally; mental drugs containing trypsin-like action.