SU1220165A1 - Device for measuring and processing parameters of blood current - Google Patents

Description

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the comparison unit contains a series-connected element AND and an element NOT, a group of elements OR-NOT, the outputs of which are connected - respectively to the inputs of the element AND, a group of elements of the comparison with the upper threshold and a group of elements of the comparison with the lower threshold, each of the elements OR-NOT the first and the second inputs are connected between the outputs of the corresponding elements in comparison with the upper and lower thresholds, the first inputs

The invention relates to medical technology and can be used to analyze and dynamically monitor the state of the cardiovascular system of a person or warm-blooded animal, by measuring and processing its blood flow parameters.

The aim of the invention is to reduce the measurement time.

FIG. Figure 1 shows a structural electrical circuit of a device for measuring and processing blood flow parameters; in fig. 2 is a structural electrical circuit of a device comparison unit; in fig. 3 is a control unit, an example of execution; in fig. 4 time diagrams of control unit voltages.

The device for measuring and processing blood flow parameters contains (Fig. 1) the first group of N measuring channels 1, connected in pairs, each of which consists of series-connected sensor 2, a generator of 3 signals and a square measuring unit 4, a group of first adders 5, a group of first dividers 6, each of which is connected by the first and second inputs between the outputs of the first and second measuring channels 1 of the corresponding pair of the first group and between the first and second inputs of the corresponding first adder 5, the display unit 7, block to the 8th control, the first output of which is connected to the additional inputs of sensors 2, the second output to the second inputs of the area measurement units 4, and the third output to the third inputs

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the second inputs are connected to the outputs of the first adders, the first dividers, the second dividers of the fourth adder and the third divider, and the second inputs are connected respectively to the outputs of the memory unit, and the outputs of the comparison elements with the upper and lower thresholds element and the element and are connected respectively to the second group of inputs of the display unit.

blocks 4, and the outputs of the first adders 5 and the first dividers 6 are connected to the corresponding inputs of the first group of the display unit 7,

the second group of measuring channels 1, the group of second dividers 9, the first inputs of which are connected to the output of the first adder from the group of first adders 5, the second inputs

the second dividers 9 in the number N / 2-1 are connected respectively to the inputs of the first adders 5, except for the first, and the second inputs of the other second dividers 9 are connected to the highlight

with the outputs of the measuring

channels 1 of the second group, the second adder 10, whose inputs are connected respectively to the outputs of the first of the corresponding measuring pair

20 channels 1 of the first group, the third adder 11, the inputs of which are connected respectively to the outputs of the second of the corresponding pair of measuring channels 1 of the first group, the fourth

 adder 12 ,. the inputs of which are connected respectively to the outputs of the second 10 and third adders 11 and measuring channels 1 of the second group, the third divider 13, the first input of which

The second input is connected to the output of the second adder 10, and the second input is connected to the output of the third adder 11, memory unit 14 and comparison unit 15, whose outputs are connected respectively to the second input group of display unit 7, the first input group to outputs 14 memory, and the second g upa inputs to the first group of inputs of the display unit 7 and to the outputs of the first sum312

mators 5, the first divisors 6, the second divisors 9, the fourth adder 12 and the third divider 13.

In addition, the comparison unit 15 contains (FIG. 2) the serially connected element AND 16 and the element NOT 17, the group of elements OR-NOT 18, the outputs of which are connected respectively to the inputs of the element AND 16, the group of elements 19 comparison with the upper threshold and the group elements 20 comparison with the lower threshold, each of the elements OR NOT 18 the first and second inputs are connected between the outputs of the corresponding elements 19 and 20 comparison with the upper and lower thresholds, the first inputs of which are interconnected and connected respectively to the outputs of the first adders 5 the first dividers 6, the second dividers 9, the fourth adder 12 and the third divider 13, and the second inputs are connected respectively to the outputs of the memory block 14, and the outputs of the elements 19 and 20 compared with the upper and lower thresholds 17 and element 16 are connected respectively to the second group of inputs of the display unit 7.

In this case, the control unit 8 can be executed, for example, (FIG. 3) in the form of serially connected current pulse generator 21, trigger 22, pneumatic pressure source 23, pressure sensor 24, comparison circuit 25, additional HE element 26 and first AND additional element 27, as well as the second additional element 28 and the start button 29 and the pressure increase regulator 30, the second input of the trigger 22 is connected to the output of the comparison circuit 25 and the first input of the second additional element 28, the second input of which is connected with the trigger output 22 and the second input of the first additional element I 27, the start button 29 is connected to the start pulse formers 21, the lift speed regulator 30 is connected to the pneumatic pressure source 23, and the pneumatic pressure source 23 outputs 27 and 28 are connected to the first, second and third output buses of the control unit 8, respectively.

The device for measuring and processing blood flow parameters works as follows.

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Sensors 2 of a physiological signal, each of which is a set of pneumatically interconnected medical occlusive cuff and a differentiating cuff pressure sensor, are fixed on the patient under test. At the same time, sensors 2 of the first measuring channels 1 of each pair of the first group are placed on the left parts of each pair of symmetric examined body parts, for example, on the head in the left temporal artery, on the left shoulder in the brachial artery, on the left leg in the femoral artery or arteries of the leg. Sensors 2 of the second measuring channels 1 of the same pairs of the first group are placed respectively on the right-hand sides of the same pairs of symmetrical examined body parts. The sensors 2 of the measuring channels 1 of the second group are fixed on the single examined parts of the body, for example, on the penis or tail (of the animal), etc.

After this, measurement and processing of the blood flow parameters are started, the control unit 8 is started up by pressing the start button 29 (Fig. 3). The control unit 8 from its first outlet performs pneumatic inflation of the cuffs of the sensors 2 from zero overpressure to some maximum pressure (130 .., 180 mm Nl

wherein the blood vessels of the body parts to be examined are completely or almost completely clamped. Boost pressure is increased at a constant speed (3, .. 6 mm Nr. Per second), the value of which is set by setting pressure regulator 30 to the pressure rise in control unit 8. At the beginning of the boost, the control pulse from the second output of the control unit 8, all the area measurement units -4 are set to the zero initial position. After the charge pressure reaches the maximum value, the cuff of the cuff automatically stops and their pressure quickly returns to the original (atmospheric) pressure. At the third output of the control unit 8, during the time of pressurization of the cuffs, a control potential is established that permits operation of the area measurement units 4.

When you press the start button 29 at the output of the shaper 21, a start-up pulse arises from the front of the coolant

front (Fig. 4), which overturns the trigger 22, which includes a source 23 of pneumatic pressurization of the pressurization of the cuffs. The current value of the linearly increasing boost pressure is discontinuously measured by pressure sensor 24, whose electrical output signal, proportional to pressure, is compared by comparison circuit 25 to the lower and upper thresholds set by the corresponding constant potentials E i. The lower threshold set by potential E corresponds to such an excess pressurization pressure (ZO.OZO mm HQ), at which the cuffs are pressed to the patient’s body and the differential pressure sensors | begin to register pressure changes in the cuffs caused by Vai pulsation of the blood in the vessels mi surveyed 20 area just an indicator of blood flow.

parts of the body. The upper threshold, set by the potential E, corresponds to the maximum pressure of the cuffs. The comparison circuit 25 forms the output unit potential if its input voltage is in the interval between the values E and E, and the potential is zero in the remaining cases. Within the length of time from triggering trigger 22 until the moment when the left blood flow reaches 30 tel

pressurization of the cuffs of the value corresponding to the lower threshold E, at the output of the first additional element I 27, is formed around the angles, GU E,

corresponding to the upper poro-, trigger 22 back front partly to the right inspected part for the same pairs of symmetrical body parts, characterizing the asymmetry of the blood supply to these couples. The second and third sum impulse of installation of blocks 4, gauges 10 and 11 determine the total area rheniums in the zero state. blood flow indicators, respectively. When the pressurization pressure reaches all left and all right symmetrical

examined body parts. The fourth adder 12 calculates the total travel potential of circuit 25, which compares the blood flow of all the symmetrical ones and returns to the initial state of the single examined parts of the body.

The third divider 13 determines the ratio of the total blood flow indicators of all the left and all the right parts 45 of the body.

The group of second dividers 9 calculates the ratios of blood flow indices of each single examined body part and total indices

and turns off the pneumatic pressure source 23. In the length of time while the pressure of the inflation of the cuffs changes from the lower to the upper threshold, a single control potential is maintained at the output of the second additional element I 28 allowing the operation of the area measurement units 4

In the process of pressurization of occlusive 50 blood flow of each of the pairs of symmetric cuffs of sensors, each differentiated body parts to be examined, to the total indicator of the blood flow of one of the pairs of symmetric examined

A cuff pressure sensor generates an electrical output signal proportional to the first derivative.

patient body parts

in time from the change in the pneumatic 55 of our example — the ratio of the total pressure in the corresponding manna indicators of the blood flow of the arms and legs and the jet caused by the pulsations of the pressure of the blood flow of the head member (tail of the blood in the obstetrician blood vessel) indicator of the part of the body covered by the manzhokrotok head).

that This signal is bipolar oscillation.

The shaper of 3 signals of each measuring channel 1 wasp;

full-time etiquette oscillation, and each area measurement unit 4 measures the total area under the corresponding curve of the 3 tachooscillations converted by the former, equal to the sum of the areas of all its peaks without taking into account their sign. The value of such an area, obtained at the end of the integration time interval at the output of each area measuring unit 4, is a parameter characterizing the intensity of blood flow in the vessel feeding the corresponding part of the body. For brevity, we will call this value

Next, the following processing of the output values of the area measurement units 4 is carried out. The group of first adders 5 calculates total ones; 25 indicators of the blood flow of each pair of symmetric examined body parts (in our example, respectively, of the head, arms and legs). The group of first dividers 6 determines the ratio of the body parts of the patient under study.

The calculated parameters characterize both the total blood flow in all the examined parts of the body, and the absolute and relative distribution of this blood flow along the selected aggregates of the examined body parts vertically (head, arms, legs) and horizontally (left and right parts and half of the body). These parameters are displayed in the form of numbers on the corresponding / O signals of the first adders 5, first digital indicators of the block 7 and second dividers 6 and 9, the fourth

indications and may be further recorded in the patient’s medical history. The device allows the implementation of a new algorithm for determining and processing blood flow parameters, which is as follows. It has been established that the average statistical ranges of the values of the indicated parameters of the blood flow, measured in healthy ones, are equal to 20

the input signal is less than or equal to the upper threshold value, and a single potential if the output signal exceeds the upper threshold. On

nodules of a given species (human, monkey, dog, etc.), gender, age group, and similar organisms with certain pathologists (in particular, cardiovascular diseases - 25 outlets of each element 20 by comparison, for example, hypertension, the atheroscleus with the lower threshold is formed by the zero rose of the vessels of the lower extremities, neurocirculatory astonia, etc.) are not the same and have characteristic grapotential, if its input signal is greater than or equal to the value of the lower threshold, and a single

Nice for each type of pathology. Poe-30 potential, if the input signal to the round is the correlation of the measured blood flow parameters of a given patient to the average statistical ranges of their changes for healthy organisms of the same type, sex and age group and organisms with known pathologies, in particular, makes it possible to carry out a differential diagnosis of the disease given

patient, and with repeated post-40, the corresponding

 indicator light (or board) which indicates confirmation of the pres ence of the presence of this disease (condition) in the patient

Informative measurements — dynamically monitoring changes in its state during treatment or as a result of other influences.

The functions of such correlation are performed by comparison block 15. To carry out this correlation, the upper and lower boundary values of the correlated blood flow parameters, which determine the average statistical ranges of their most likely changes (with a given probability level) for the suspected pathology, are entered into memory block 14, for example the presence of atherosclerosis of the lower extremities in the patient under study with infusion stenosis

Terry, (The boundaries of the named ranges for the selected probabilities of the correct, the decisions are made in advance based on the results of the relevant extensive studies of patients with this disease and the statistical processing of the measurements performed on similar parameters of blood flow). B block 15 comparison (Fig. 2) weekend

the adder 12 and the third divider 13 are compared using the corresponding comparison elements 19 and 20 with the upper and lower thresholds (boundary values) of the matched parameters entered in the memory unit 14. At the output of each element of the comparison with the upper threshold, the shape of the input signal is less than or equal to the value of the upper threshold, and the unit potential if the output signal exceeds the upper threshold. On

the output of each element 20 of the comparison with the lower threshold is formed zero

the output of each element 20 of the comparison with the lower threshold is formed zero

potential, if its input signal is greater than or equal to the lower threshold value, and the unit

that

is lower than the lower threshold. As a result, if each of the compared parameters of the blood flow falls within the range established for it, a single potential is formed at the output of each element OR-HE 18. Then the same potential is formed at the output of the element And 16. Under its influence in block 7

 indicator light (or scoreboard), which indicates confirmation of the assumption about the presence of this disease (condition) in the patient under study.

-If at least one of the blood flow parameters associated with the boundary values does not coincide with the range established for it, the output potential of the corresponding element OR NOT 18 forms a zero potential. The same potential is also formed at the output of the element AND 16, and at the output of the element HE 17 through 5 is a single potential. Under

its influence in the display unit 7; the other indicator lamp (board) lights up, which signals that the checked object is not confirmed

position on the n1sh state of the studied patient. The output potentials of the elements YLI-NE 18 and the elements 19 and 20 of the comparison with the upper and lower thresholds are also controlled by the corresponding auxiliary (specifying) indicator lights of the display unit 7. If the tested assumption is confirmed, then at the outputs of all elements OR NOT 18 uniform control potentials are formed, and at the outputs of all elements 19 and 20 compared with the upper and lower thresholds there are zero potentials. As a result, all the auxiliary indicator lamps in OR-NOT 18 elements are checked, and all the lamps associated with elements 19 and 20 will not be lit against the upper and lower thresholds. If the tested assumption is not confirmed, auxiliary lamps are lit, controlled by the same elements 19 and 20 comparison with faith, threshold and lower thresholds, the output potentials of which are single due to the corresponding parameter being compared beyond the limits of the range set for it. auxiliary indicator lights of the corresponding elements OR NOT 18 o will not light up. This allows you to easily see and record which of the compared blood flow parameters of the test the patient does not fall within the DP them dia: pazony and which side of these ranges, they are deflected.

Specific values established for each tested assumption of the average comparison ranges and the totality of the examined body parts of the examined patient are set either by the physician or by a separate tool prepared in advance based on the available statistical data on the distribution of the measured blood flow parameters to determine pathologies (conditions) this type of organism. In the presence of such an instruction, unqualified personnel, including the patient himself, at home, can also work with the device for measuring and processing blood flow parameters.

When dynamically monitoring the state of the same patient (or experimental animals), the upper and lower limit values of the compared parameters can be set for reasons of detecting the direction and speed of their normalization or destabilization under the influence of various influences (including drugs).

The use of a device for measuring and processing blood flow parameters in clinical practice will significantly reduce the time of examination of patients with cardiovascular diseases and, thereby, shorten the duration of their stay in the clinic, reduce the cost of treatment and increase the efficiency of diagnosis.

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FIG.

Stuod 21

you 93 12

Ym od 2t

Item 25

exit 28

Editor A.Ivanova

Compiled by E. Baluyev

Tehred M. Khodanich Proofreader M. Sharoshi

Order 1813/1 Circulation 596 Subscription

VNIIPI USSR State Committee

for inventions and discoveries 113035, Moscow, Zh-35, Raushsk nab., 4/5

Production and printing company, Uzhgorod, st. Project, 4

Fmg

Claims (2)

1. DEVICE FOR MEASURING AND PROCESSING BLEEDING PARAMETERS, containing the first group of N measuring channels, connected in pairs, each of which consists of a series-connected sensor, a signal shaper and an area measuring unit, a group of first adders, a group of first dividers, each of which is the first and second inputs included between the outputs of the first and second measuring channels of the corresponding pair of the first group and between the first and second inputs of the corresponding first adder, an indication unit and a control unit the first output of which is connected with additional inputs of the sensors, the second output is with the second inputs of the area measuring units, and the third output is with the third inputs of the area measuring units, and the outputs of the first adders and first dividers are connected to the corresponding inputs of the first group of the display unit, characterized in that, in order to reduce the measurement time, a second group of measuring channels, a group of second dividers, the first inputs of which are connected to the output of the first adder from the group of first sums, are additionally introduced into it mators, the second inputs of the second engines in the amount of N / 2-1 are connected respectively to the outputs of the first adders, except for the first, and the second inputs of the remaining second dividers are connected respectively to the inputs of the measuring channels of the second group, the second adder, the inputs of which are connected respectively to the outputs of the first of the corresponding - a pair of measuring channels of the first group, the third adder, the inputs of which are connected respectively to the outputs of the second from the corresponding pair of measuring channels of the first group, the fourth adder, whose moves are connected respectively to the outputs of the second and third adders and measuring channels of the second group, the third divider, the first input of which is connected to the output of the second adder, and the second input to the output of the third adder, a memory unit and a comparison unit, the outputs of which are connected respectively to the second group inputs of the display unit, the first group of inputs to the outputs of the memory unit, the second group of inputs to the first group of inputs of the display unit and to the outputs of the first adders, first dividers, second dividers, fourth sum torus and third divisor. 2. The device pop. 1, characterized in that in it the comparison unit contains a series-connected AND element and an NOT element, a group of OR-NOT elements, the outputs of which are connected respectively to the inputs of an AND element, a group of comparison elements with an upper threshold and a group of comparison elements with a lower threshold, each of the OR-HE elements, the first and second inputs are connected between the outputs of the corresponding comparison elements with the upper and lower thresholds, the first inputs of which are interconnected and connected respectively to the outputs of the first adders, first things Iteli, the second dividers ^ the fourth adder and the third divider, and the second inputs are connected respectively to the outputs of the memory unit, and the outputs of the Comparison elements with upper and lower thresholds, the elements OR-HE, the element NOT and the element AND are connected respectively to the second group of inputs of the display unit.