SU1178408A1 - Method of differential diagnosis of the primary and secondary hypogonadism of the male - Google Patents
Method of differential diagnosis of the primary and secondary hypogonadism of the male Download PDFInfo
- Publication number
- SU1178408A1 SU1178408A1 SU833648537A SU3648537A SU1178408A1 SU 1178408 A1 SU1178408 A1 SU 1178408A1 SU 833648537 A SU833648537 A SU 833648537A SU 3648537 A SU3648537 A SU 3648537A SU 1178408 A1 SU1178408 A1 SU 1178408A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- primary
- patient
- increase
- secondary hypogonadism
- hypogonadism
- Prior art date
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
СПОСОБ ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКИ ПЕРВИЧНОГО И ВТОРИЧНОГО ГИПОГОНАДИЗМА У ЛИЦ МУЖСКОГО ПОЛА .путем введени больному лекарствен-ных препаратов, воздействующих на секрецию лютинизирующего гормоотличающийс на. тем. что, с целью повьшени точности диагностики, больному ввод т нифтолид перорально в дозе 10 мг/кг массы тела в сутки, определ ют суточную экскрецию лютеинизирующего гормона с мочой через 3-5 сут и при увеличении этого показател более чем в 1,5 раза от исходного уровн диагностируют первичный гипогонасл дизм, а при увеличении менее, чем в 1,5 раза - вторичньш гипогонадизм .METHOD OF DIFFERENTIAL DIAGNOSTICS OF PRIMARY AND SECONDARY HYPOGONADISM IN THE FACE OF THE MALE FLOOR. By administering drugs to the patient that affect the secretion of lutealizing hormone that is different. topics that, in order to improve the accuracy of diagnosis, the patient was administered nifolide orally at a dose of 10 mg / kg of body weight per day, determine the daily excretion of luteinizing hormone in urine after 3-5 days and with an increase of more than 1.5 times the initial level is diagnosed with primary hypogonasdism, and with an increase of less than 1.5 times, secondary hypogonadism.
Description
slsl
00 4 1 Изобретение относитс к медици й в частности к эндокринологии, и может быть использовано дл диагностики мужского гипогонадизма. Целью изобретени вл етс повышение точности диагностики. П р и м е р 1. Больной 19 лет, поступил в клинику дл уточнени диагноза гипогонадизма. У больного была собрана суточна моча и в ее аликвоте бьшо определено содержание лютеинизирующего гормона (ЛГ) по методу Wide. Результат 58 ,1 МЕ/сут. В течение трех дней больной принимал внутрь через 20 мин после еды нифтолид по полтаблетки (125 мг) 3 раза в день. На третьи сутки приема нифтолида у больного собирали суточную мочу. Пр повторном определении ЛГ бьшо установлено , что зкскреци гормона составл ла 87 МЕ/сут. Таким образом, увеличение экскреции ЛГ превысило исходньй уровень в 1,54 раза. На основании результатов пробы был 8 поставлен диагноз первичного гипогонадизма . Последующее комплексное клинико-лабораторное исследование подтвердило диагноз первичного гипогонадизма . Пример 2. Больной 16 лет, поступил в клинику с целью уточнени диагноза и назначени патогенетической терапии. В собранной суточной моче было определено содержание ЛГ, по Wide - 8,2 МЕ/сут. Больной в течение 5 дней принимал нифтолид по 3/4 таблетки (180 мг) 3 раза в день через 20 мин после еды. В суточной моче, собранной на п тые сутки приема нифтолида, вновь было проведено определение ЛГ. Результат:9,0 МЕ/сут на п тые сутки. Отсутствие прироста экскреции ЛГ свидетельствует об истощении функциональных резервов гипоталамо-гипофизарной системы. На основании полученных данных бьш поставлен диагноз вторичного гипогонадизма .00 4 1 The invention relates to medicine, in particular, to endocrinology, and can be used to diagnose male hypogonadism. The aim of the invention is to improve the accuracy of diagnosis. PRI me R 1. A patient, 19 years old, was admitted to the clinic to clarify the diagnosis of hypogonadism. The patient was collected daily urine and in its aliquot was determined by the content of luteinizing hormone (LH) according to the method of the Wide. Result 58, 1 IU / day. For three days, the patient took orally 20 minutes after eating nifolid half a tablet (125 mg) 3 times a day. On the third day of taking niftolide, daily urine was collected from the patient. In the repeated determination of LH, it was established that the hormone secretion was 87 IU / day. Thus, the increase in LH excretion exceeded the baseline level by 1.54 times. Based on the test results, 8 was diagnosed with primary hypogonadism. A subsequent comprehensive clinical and laboratory study confirmed the diagnosis of primary hypogonadism. Example 2. A 16-year-old patient was admitted to the clinic for the purpose of clarifying the diagnosis and prescribing pathogenetic therapy. The content of LH in the collected daily urine was determined; for Wide - 8.2 IU / day The patient took nftolid 3/4 tablets (180 mg) 3 times a day 20 minutes after meals for 5 days. In the daily urine collected on the 5th day of nifoldide intake, the LH was again determined. Result: 9.0 IU / day for the fifth day. The lack of increase in the excretion of LH indicates the depletion of the functional reserves of the hypothalamic-pituitary system. Based on the data obtained, secondary hypogonadism was diagnosed.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU833648537A SU1178408A1 (en) | 1983-07-27 | 1983-07-27 | Method of differential diagnosis of the primary and secondary hypogonadism of the male |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU833648537A SU1178408A1 (en) | 1983-07-27 | 1983-07-27 | Method of differential diagnosis of the primary and secondary hypogonadism of the male |
Publications (1)
Publication Number | Publication Date |
---|---|
SU1178408A1 true SU1178408A1 (en) | 1985-09-15 |
Family
ID=21084043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU833648537A SU1178408A1 (en) | 1983-07-27 | 1983-07-27 | Method of differential diagnosis of the primary and secondary hypogonadism of the male |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU1178408A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2712180C1 (en) * | 2019-07-25 | 2020-01-24 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Diagnostic method of central hypogonadism in females |
-
1983
- 1983-07-27 SU SU833648537A patent/SU1178408A1/en active
Non-Patent Citations (1)
Title |
---|
M.E.Shoep, H.Doorenbos, W.S.de Zande: The effect of LK-RH infusion on serum LH, FSH, and tesbosterone .in boys with advanced Puberty, delayed puberty and hypogona dotrophic hypogonadiem, Acto and ocrind, (KGh) , 1978, 89, 2, 209-216. * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2712180C1 (en) * | 2019-07-25 | 2020-01-24 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Diagnostic method of central hypogonadism in females |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Willis et al. | Greater inhibition of the pituitary–ovarian axis in oral contraceptive regimens with a shortened hormone-free interval | |
Fichman et al. | Diuretic-induced hyponatremia | |
Lachelin et al. | Hypothalamic chronic anovulation | |
Freeman et al. | Incidence of thyroid dysfunction in an unselected postpartum population | |
Turnbull et al. | Relationships between symptoms, menstrual cycle and orocaecal transit in normal and constipated women. | |
Bartholomew | A long-acting phenothiazine as a possible agent to control deviant sexual behavior | |
Kreek et al. | Analyses of methadone and other drugs in maternal and neonatal body fluids: use in evaluation of symptoms in a neonate of mother maintained on methadone | |
Schulhafer et al. | Steroid-induced Kaposi's sarcoma in a patient with pre-AIDS | |
Hull | The Effects of Hormonal Contraceptives on Lactation: Current Findings, Methodological Considerations, and Future Prorities | |
Samantray et al. | Landry‐Guillain‐Barré‐Strohl syndrome: A study of 302 cases | |
Beck et al. | Observations on the regulatory mechanisms of aldosterone secretion in man | |
Jayson et al. | Thyrotoxicosis and Hashimoto goitre in a pair of monozygotic twins with serum long-acting thyroid stimulator | |
Markovitz | Acute intermittent porphyria: a report of five cases and a review of the literature | |
HODGES et al. | Factors Affecting Human Antibody Response: III. Immunologic Responses of Men Deficient in Pantothenic Acid | |
Frank | The role of the female sex hormone | |
GLASS et al. | Intestinal absorption and hepatic uptake of radioactive vitamin B12 in various age groups and the effect of intrinsic factor preparations | |
Harkness et al. | The serum leucine aminopeptidase test | |
Ehrlich et al. | The use of chlorpropamide in diabetes insipidus in children | |
Pearson et al. | Pernicious anemia with neurologic involvement in childhood: Report of a case with emphasis on dangers of folic acid therapy | |
SU1178408A1 (en) | Method of differential diagnosis of the primary and secondary hypogonadism of the male | |
Cruickshank et al. | The relationship of total and differential leukocyte counts with urinary oestrogen and plasma cortisol levels | |
Corcoran et al. | Tetracycline for acne vulgaris and possible teratogenesis. | |
Hausmann et al. | Biochemical effects of short-term treatment with carbenoxolone disodium. | |
Lockhart et al. | The effect of pregnancy and puerperium on the thiamine status of women | |
RABINER et al. | The urinary excretion test in the diagnosis of Addisonian pernicious anemia |