SU1161066A1 - Foddrer additive for swine - Google Patents

Abstract

The use of caprylic zinc as a feed additive for pigs. (L with

Description

but:

about. The invention relates to the feeding of animals, in particular to feed additives for increasing the efficiency of growing and fattening pigs. The purpose of the invention is to find a more efficient feed additive for pigs from the group of organic zinc compounds. Zinc caprylic acid (zinc caprylate), white amorphous powder, code 220142, TU 6-09-0922 76, contains 17.7% zinc. This salt is poorly soluble in water (62% of the taken amount of zinc in the form of caprylate. Goes into solvent at 37 s), soluble in 0.4% hydrochloric acid (HCE concentration in the gastric juice of pigs} and in 2 n hydrochloric acid, The pH value of the aqueous solution of zinc caprylate is acid 6.03. Zinc caprilat has the structural formula: CH3 (CH2-) b-C eu5 (: sn2) b-cIon zinc (Zn) forms a salt with caprylic acid, in which the type of bond is ion Capriculum acid is found in many growing fats and animal fats. For example, its content in milk fat is 1-4%. Capr zinc acid is used in analytical chemistry .. Zinc caprilat xopowo dissolved in the contents of the gastrointestinal tract, is a normal part of the body of animals, anaprilic acid plays an important role in the metabolism of lnpidov. All these properties determine the high efficiency of capric acid zinc 1 as a feed additive Example 1. The effectiveness of the proposed compound as a feed additive was confirmed in experiments carried out on large white breeds 3-4 months old. The animals received a semi-synthetic diet (PSR) in which the content of nutrient, mineral and biologically active substances corresponds to the existing feeding standards for young pigs (Table 1). The mineral premix contained magnesium, potassium, iron, copper, manganese, cobalt, selenium, iodine and starch. As a filler. Vitamin premix consisted of vitamins A, Dd, E, K, C, BZ, B, R / B .. J.J, folic i-paraamine benzoic acids, oxytetracin, furazolidone and starch as a filler. Daily feed rate was given twice a day. Animals received distilled water with a content of 0.015% sodium chloride. Before staging the piglet for fourteen days, jITCP was obtained without the addition of zinc. During the period of the experiment, the animals consumed the same amount of feed, the consumption of which was 100%. At the age of 90 days, the pigs were divided into thirteen groups of 3 heads each. The first group received PSR without zinc additives, the content of which was 7.2 mg / kg of air-dry substance of the feed, the second group received PSR + 50 mg of zinc / kg of feed in the form of sulfate salt (), which served as the standard compound as the most the common addition of this element to the PSR of group III animals was injected with 50 mg of zinc / kg of feed in the form of caprylic acid salt. TABLE 1 Composition of semi-synthetic ration for pigs of 3-4 months of age Cellulose (powder from de-ash filters) 4.0 Pork fat3.0 Sunflower oil2.0 To confirm the effectiveness of the proposed additive, zinc digestion from various compounds: from inorganic salts (anhydrous sulfate, chloride, nitric acid, basic carbonate), metallic zinc, oxygen complexes (acetate), and zinc chelates with methionic, tryptophan, phytic acid and EDTA). Methioninate, tryptophan and phytate zinc were synthesized in our laboratory. All compounds were injected into the PSR in the composition of the mineral premix in the amount of 50 mg / kg core. The particle size of all the tested compounds was the same 100-125 microns. The method of studying the bioavailability (BD) of zinc from chemical compounds is as follows: Animals for 2 days. kept on a hungry diet, and then for 7 days. give PSR without the addition of zinc (the first group), and PSR + -the compound to be studied (third group). In the course of the last three experiments, an account was taken of the consumption of Korma, water, feces and urine. In the taken samples, the zinc content is calculated by calculating the value of the elemental deposition in the body, the DB, and the absorption assimilation using the formulas: Deposition - f 2 (h) -K2 (, G% h, - K, -M, mg / head / su deposition of zinc from the studied compound deposition of zinc from the standard compound / 100,% i true absorption, nKt-E, 100,%, the amount of zinc consumed, mg / head / day; the amount of zinc excreted with feces, mg / head / day ; amount of zinc excreted in urine, mg / head / day; endogenous loss of an element with feces, mg / head / day} 1,2,3 - respectively I, II, III groups of animals. Fire losses of zinc with feces were determined in additional experiments on synthetic rations and starving pigs. The value of endogenous losses was 75.5 µg / kg of body weight per day. On PSR without the addition of zinc, the amount of element deposition was 2.95 tO, 27 mg in per day or 0.15 mg / kg body weight per day. The results of studying different parameters of digestion and zinc BD are given in Table 2. As can be seen from Table 2, only the negligent compound of zinc with methionine is slightly (, 05) superior to zinc caprate by assimilation and DB. However, it should be noted that the production of methionine, zinc in our country has not yet been adjusted. In addition, methionine is an essential amino acid and its use in combination with zinc can lead to an imbalance of protein nutrition. The digestibility and DB of zinc from cadrium salt of acid is significantly higher (P = 0.01) than from sulfate, triptanate, acetate, and other compounds of this element, which indicates a high biological efficiency of the proposed additive. From tab. 2 it also follows that the zinc DB from caprylic acid salt is 31.7% higher than from 7-aqueous sulfate. This means that using caprylic acid salt, it is possible to reduce the rate of zinc input into the pigs ration by 30%, i.e. from 50 to 35 mg / kg feed. The total zinc saving over the periods of rearing and fattening of pigs (26-222 days) will be 4 kg of zinc per 1 head. In terms of zinc sulphate 7-water, it is 17.6 kg of salt. The increase in the mass of pigs (Table 3), the incapacitated pSPR with the addition of Inca caprylate, was 27.5% higher (, 01), when the enrichment of the ration was carried out with sulfate salt. Cheating compounds of cin with tryptophan and methionine have no advantages over the proposed

$ 1161066 6

by their effect, neither growth in the effective assimilation and utilization of feed. The consumption of feed in all the trace elements, nutrients of the groups is the same (1.1 kg) .: feed that contributes to the growth, the use of capricious effect on the growth of zinc acid contributes to more eff- 5 monitors.

Biological availability of zinc from various compounds in growing pigs

table 2

Sulfuric acid, 7-water Methioninate Kaprilovokisla Tryptophan acetic acid, 2-water EDTA-zinc chloride; - water Zinc, Nitrate Powder, 6 Water W / O Solnokisla, anhydrous

Carbonic acid is basic, 1-water

Figat

 The difference is significant compared with 7-water zinc sulfate.

. T a b l and c a 3

Live weight dynamics of piglets receiving various zinc compounds

PSR without zinc supplements 29,

PS + sulfate zinc

water (standard

rupp 32.1

222 1 29

31.4

91.0

2D4 110

34.3

100

The difference is significant compared with the standard group. Example 2 In order to confirm the advantages of the proposed compound over the known (zinc methioninate), a second experiment was conducted on young pigs of a large white breed 3-4 months from the age. The animals were supplemented with a semisynthetic ration (PSR), in which the content of nutrient, mineral and biologically active substances corresponds to the existing feeding standards of young pigs. Animals were divided into four groups of 10 animals each according to the principle of analogues. The experiment lasted 31 days. The first group received PSR without the addition of zinc, the content of which was 7.2 mg / kg of air-dry substance of the feed, the second group received PSR + 50 mg / zinc / kg of feed in the salt-sulphate salt (ZnS04 H O) which served as standard Intensity growth growth and their use of feed chemical form of zinc in p 1-PSP without ext. zinc wok22.0 + 1.03 33.0 + 1.85 1-PSP + Sulfate (control) 22.0 + 0.85 34.8 + 0.84

2.90 2.49% compound as the most common additive of this element (control). In the PSR, animals of the third group were injected with 50 mg of zinc / kg of feed in the form of caprylate, and in the PSR of the fourth group, 50 mg of zinc / -kg of feed in the form of methioninate (Table 4). As can be seen from the table. 4, contain more pigments on PSR without zinc additives that led to a significant deterioration in growth rate and feed utilization efficiency, however, the difference between the first and second pears was not significant. The inclusion of zinc caprylate in the PSR led to an increase in live weight of pigs at the end of the experiment by 2.4 kg compared with the control (P 0.05). The difference in live weight between the third and fourth groups was 1.3 kg or 3.6%. 4 months of age depending on non (n 10) Table 4 355 + 291.03 413 -181.03 iTf-nCP-1-kaprilat 22,511.01 37,210.75 W-PSR + methioninate 22.6 ± 0.64 35.910.48 - The difference is significant compared with - the difference is significant between W and N

The average daily weight gain of 20% of the top group of third group treated with zinc caprylate was significantly higher by 61 g or 10.5% compared with group IV (P 0.05) treated with zinc methioninate (basic object). 25 Consumption of consumption in all groups was the same: G, 03 kg / year per day. Eff () feed efficiency

ten

1161066 Continuation of table 4

It was the tallest group in the third group.

Therefore, the use of zinc caprylate contributes to a more efficient absorption and use of zinc, nutrients of the feed in the body, which has a positive effect on the growth of animals. 474120 1.032.17 429 + 11 1.032.40 j group (, 05), groups (Р 0.05), (Р 0.05).

Claims (1)

The use of caprylic zinc as a feed additive for pigs,. ’. 990191Г'Τϊ§ · ^{, 6,>} 1 1161066 2