SU1141296A1 - Device for filling small-volume trays of flow-through type - Google Patents

Abstract

A DEVICE FOR FILLING FLOWS OF THE SMALL VOLUME QUANTUM,%; -.W -x-- /. / holding a flow cell with a meter, channels for supplying fluid with a movable intake spout, channel for draining fluid with a dehumidifier, and f) a filling device, characterized in that, in order to simplify the design of the device, the device for filling is designed as a hollow cylinder with a base, inside the cylinder there is a piston with a rod, a sleeve with a spring is placed on the rod, the sleeve is connected to the body with the possibility of movement, and the rod is equipped with a stop, a regulating nut and placed between it and drive plug.

Description

go

with

Od

"one

The invention relates to medical laboratory technology and is intended to fill a small volume of the measuring cuvette with a reaction mixture during biochemical analyzes,

A device for filling small flow cells of a small volume is known, comprising a flow cell with a meter, channels for supplying fluid with a movable intake spout, a channel for diverting fluid with a moisture separator, and a device for filling .LO.

A disadvantage of the known device is the complexity of the design, due to the presence of the spool valve and two interconnected piston devices, which in turn does not ensure the high reliability of the device. In addition, after draining the liquid, a drop of liquid remains at the end of the intake spout, which contaminates the subsequent bioassay, thereby reducing the measurement accuracy.

The purpose of the invention is to simplify the design of the device.

This goal is achieved by the fact that in a device for filling small flow cells, containing a flow cell with a meter, channels for supplying fluid with a movable suction tip, channel for diverting fluid with a dehumidifier and filling device, the latter is made in the form of a hollow cylinder with a base, inside the cylinder there is a piston with a rod, a sleeve with a spring is placed on the rod, the sleeve is connected to the housing with the possibility of movement, and the rod is equipped with a stop, a regulating nut and a spacer I forward them drive fork

FIG. 1 is a schematic diagram of the device; in fig. 2 different positions of the cycle of the device

Position I marked filling the cuvette; on position II - the main, sample discharge; at position iil - npo duvka air lines; At position IV, the piston is reset to its original position.

Flow cell 1 with meter 2 has channels 3 and 4 for the supply and discharge of fluid. A fluid intake nozzle 5 is connected to channel 3 for supplying liquid, which is lowered in the terminal 962.

bone 6 with the reaction mixture. A channel 4 for draining the fluid through the dehumidifier 7 is connected to the cavity of the piston device 8, a spring 10 is installed on the rod 9 of the piston device, one end of which rests on the housing 11, and the second is placed in the sleeve 12 suspended from the housing 11 on the studs 13 and 14, At the end of the rod 9, the stop 15 is fixed and the adjusting nut 16 is installed, the displacement of which regulates the stroke of the piston 17, the piston rod 9 of the piston device is driven by a fork 18 connected to a drive (not shown).

The device works as follows.

Before starting to measure the reaction mixture, the intake nozzle 5 is lowered into the tank 6. When the drive is turned on, the fork 18 moves downward, moving the piston 17 to the lower position (pos. I), as a result of which a vacuum is created in the cavity of the piston device 8. the mixture from the tank 6 enters the inlet pipe 3 and fills the cavity of the measuring cell 1. When the actuator plug 18 moves upward from the adjusting nut 16 to the stop 15, the piston is in a stationary state and at this time the reaction mixture is measured and in cuvette 1,

At the same time, the pick-up nozzle 5 rises from the tank 6. When in contact with the stop 15, the plug 18 moves the piston 17 upward, due to which the fluid flows from the cavity-cavity 1 and channels 3 and 4 into the tank 6 (pos. II). When the stop 13 is in contact with the sleeve 12, the spring 10 is compressed, and upon further upward movement of the piston 17, the lines of the cuvette are purged with air from the piston cavity

device 8 (pos. III);

When the actuator fork 18 moves down to its original position due to the action of the spring 10, the piston 17 moves downward by a distance fixed by the studs 13 and 14, air is drawn into the cuvette main through the nozzle 5, simultaneously drawing a drop of liquid in the pipeline the end of the intake nozzle during the discharge of the liquid, which reduces the contamination of the subsequent measured bioassay (pos. IV). The proposed design of the device is more compact and small in comparison with the known. In addition to 1,412,964, it provides a higher accuracy of measurement, since it eliminates contamination of the subsequent sample with a previous drop of liquid, which forms during the discharge of liquid from the spout into the container with the reaction mixture.

J t

Claims (1)

DEVICE FOR FILLING FLOW CUVETS OF SMALL VOLUMES, containing a flowing cuvette with a meter, channels for supplying liquid with a movable intake nozzle, a channel for draining liquid with a moisture separator and a filling device, characterized in that, in order to simplify the design of the device, a device for filling made in the form of a hollow cylinder with a base, a piston with a rod is placed inside the cylinder, a sleeve with a spring is placed on the rod, while the sleeve is movably connected to the housing, and the rod is equipped with Porom regulating nut and disposed between the fork actuator. 4 ^ ND ί