SU1122340A1 - Filtering material for liquid clarification - Google Patents

Description

to to

The invention relates to pulp and paper production, in particular to the production of filter materials, and can be used in the medical industry for the purification of viral vaccines. Filtration materials based on mineral asbestos and cellulose fibers, inactivated by surface-active substances to reduce the sorption of viruses, are known. However, when filtering virus-containing fluids through such flux, large amounts of calcium, magnesium, iron, and other impurities are washed out, drugs are contaminated and negatively affect the biological activity of antigens. A filtering material for clarifying a virus-containing fluid is also known, which is a polymer film, the pore system of which is formed by the bombardment of heavy cores (core filters) C2. The drawback of nuclear filters is that they quickly clog up when filtering viral suspensions filtering through them is small. The closest to the invention of the technical essence and the achieved result is a filtering material for clarifying mineral asbestos and cellulose fiber liquids, which allows filtering viral suspensions at a high speed and satisfactorily cleansing the CWS liquid. t significant loss of viruses. The aim of the invention is to increase the throughput with respect to viruses when clarifying a virus-containing liquid. This goal is achieved by the fact that (| mlting material contains glass or basalt fiber as mineral fibers, and native cotton fiber as polyfluoric acetate as cellulose fibers in the following ratio of components, wt.%: Glass or basalt fiber 65-90 Native cotton fiber 8-30 Polyvinyl acetate 2-5 Reducing the content of glass and basalt fibers in the composition of the filter material (less than 65%) and increasing the content of native cotton fiber more than 30% leads to a decrease in The degree of clarification of the filtrate and titer (fluorescent virus flu), indicating a loss of the influenza virus. The decrease in fluid clarification can be explained by increasing the average pore diameter in the material with the addition of thicker cotton fibers, resulting in dispersed particles passing through the cardboard into the filtrate. Loss of the influenza virus is caused by their i retention in the swollen native cotton fibers, which have a high spike in the swollen state (glial surface with a large number of microcracks. An increase in the composition of the lithal material of glass fibers, as well as basalt, by more than 90% and a decrease in the content of cotton fiber of less than 8% causes a decrease in the titer of the filtrate of the influenza virus (virus loss). This can be explained by the fact that thin glass and basalt fibers in an amount of more than 90% form a dense structure, causing retention of the influenza virus in small pores. With an increase in the content of polyvinyl acetate (PVA) in samples of more than 5% of INSHORET, reduction of clarification of the viral fluid, since PVA contributes to the formation of large pores in the material, with a decrease in the content of PVA B in samples less than 2% (options A and 9) 0.5 MPa value required for normal material operation. The PVA is introduced into the compound in the form of an aqueous solution (polyvinyl acetate dispersion). Polyvinyl acetate dispersion (GOST 18992--73) is an aqueous solution of the polymer in the form of globules having a size of 0.1-0. 5 microns. The concentration of the dispersion at its dosage to the fibrous components is 10%. The PVA particles dissolved in water (water dispersion J, have a negative value of the electrokinetic potential at the interface between the solid and liquid phases. Therefore, the use of PVA as a /; in the junction of the substance affects the surface charge of native cotton cellulose, glass and basaltic fibers, having a negative surface charge. This eliminates virus sorption during filtration due to electrokinetic effects. During the manufacturing process, the PVA material is deposited on the surface with a fiber. cure, which contributes to the improvement of the mechanical strength of the material.The ultrafine glass fibers with a diameter of 0.65-0.15 μm of the grade M are used as fibrous components according to TU 6-11-389-76, an ultrathin basalt fiber with a diameter 0.95 µm PCT USSR 5013-76, as a native cotton fiber, take the lint according to GOST 38180-72 of the first type 3 type with a staple length of 6-7 mm. and the end of the 1 st. 1 .1.5%, to obtain a fibrous suspension with a fiber length of 1.50: 160 dzg pparatu Ivanov. Basal fiber fiber diameter 0.95 microns

Composition composition

Option 04 is milled into analogs of the same conditions, but at pH 7. The native cotton fiber is milled in a roll at a concentration of 1-2% to 25 SR. The composition is made in the mixer of a sheet-removal apparatus. Before casting, 10% aqueous dispersion of water is introduced into the composition in Rada. The mass concentration before casting doyods is up to 0.6. -0.7%. Samples are cast on a LOA-2 sheet removal apparatus using a No. 16 mesh, on which samples of material are dried to a dryness of 5-6%. Further dewatering of the material samples is carried out on a roller press between the felt. The pressure during the pressing of 2 kgf / cm according to the pressure gauge on the pneumatic drive of the rolls. The dryness of the samples of filter material after pressing is 2830%. Next, the samples are dried on an electric dryer at 90-95 s until complete removal of moisture. Example I. According to the proposed method, a filtering material is prepared with different content of PVA. In tab. Figures 1 and 2 show the composition of samples and their properties. Table I

65 75 90 95 Glass fiber60 Basalt fiber Native cotton fiber35 30 22 PVA6 5 3 60 65 75 90 95 35 30 2283 65321

Table 2 7 1 Only when the PVA content is 2-5%, the filtering material allows satisfactory clarification of the suspension without loss of viral activity. . Besides. (Table 2) speed (filtration through the proposed material and the amount of water missed

until complete clogging of the pores, 9, the value of their properties. 5532 Native cotton fiber 35 30 228 but

1000

2.20 Satisfied0, 70 Unsatisfied- 1: 256

170

0.70 Satisfied170

0,70 Same

G70

Table 3

Table 4

1: 128

1: 256 1:16 1: 32 body

1:64 body 1: 128 1:32

1: 256 1: 256 full

1: 64 1:64 0 but higher than through a nuclear filter. The latter is quickly clogged. Example 2. According to the proposed method, filter materials are prepared with different content of glass and basalt fibers. In tab. 3 and 4 are presented. Compositional compositions of samples and 255322 3 35 30 22 83

Famous

1122340

ten

 Continuation of table 4

Continued table. four

n

12

1U2340

Continued table. four

Claims (1)

FILTERING MATERIAL FOR LIGHTENING LIQUID, containing cellulose and mineral fibers, characterized in that, in order to increase the throughput with respect to viruses when clarifying a virus-containing liquid, it additionally contains polyvinyl acetate, glass or basalt fiber as mineral fibers, and cellulose fibers as mineral fibers - native cotton fiber in the following ratio of components, wt.%: Glass or ba FROM salt fiber 65-90 9 Native cotton Ι / Λ fiber 8-30 TO? Polyvinyl acetate 2-5 ^from 1 about > j 1122340