SU1119660A1 - Method of prophylaxis of infection of abdominal cavity in operations on gastrointestinal track - Google Patents

Abstract

A method of preventing the infection of the abdominal cavity in gastrointestinal tract operations by administering antibacterial agents, characterized in that, in order to prevent infection of the abdominal cavity, the antibacterial agent is injected into the place of the intestinal tract by the intestinal tract. CO o: O)

Description

This invention relates to medicine, namely abdominal surgery, and concerns methods for preventing infection of the abdominal cavity.

There is a method for preventing infection of the abdominal cavity by injecting antibacterial agents into the abdominal cavity, muscle and bloodstream 1.

However, this method does not suppress infection in the gut in the suture area. As a result, the latter, penetrating the abdominal cavity through stitched tissues, causes in some patients various bacterial complications (peritoneal adhesions, peritonitis, etc.).

There is a method for preventing infection of the abdominal cavity during operations on the gastrointestinal tract by administering antibacterial agents 2.

However, the known method does not allow to create in the postoperative period the highest concentration of antimicrobial drugs in the gastrointestinal lumen. intestinal tract locally in the area of the intestinal suture, it is not applicable for emergency operations and is associated with repeated administration of large doses of antimicrobial agents, which leads to the development of dysbacteriosis, candidiasis and other complications in some patients.

The aim of the invention is to prevent infection of the abdominal cavity.

The goal is achieved by the fact that according to the method of preventing infection of the abdominal cavity during operations on the gastrointestinal tract by injecting antibacterial agents, the antibacterial agents are injected into the place of the intestinal suture over the intestinal lumen.

The drawing shows the localization of the injected antimicrobial agents in the lumen of anastomosing gut segments after overlapping.

The method is implemented in the following way.

Of the possible ways of introducing antimicrobial agents into the lumen of the operated organ (in solution, powder, tablets, candles), the easiest and most convenient is to inject them in the candles. Therefore, as an example, here is the method of administering 2 antimicrobial agents in suppositories.

During the operation, for example, applying a small intestine to the patient, after the formation of the posterior wall of the anastomosis through the operative wound of the intestine into the proximal

The Q Department of the anastomosing gut administered a candle based on cocoa butter containing 2 g kanamycin, 2 g levomycetin and 0.5 g furatsilin. The candle has the appearance of a stick with a diameter of 1 cm and a length of 8-9 cm. After the candle is inserted, the overlap is completed.

5 Cocoa butter is dissolved under the influence of body temperature, and antimicrobial agents are deposited in the lumen of the intestine in the area of 8-lO.cjyi on both sides of the joint. As a result, microflora

Q in the lumen of the anastomosing portions of the intestine is suppressed and infection of the abdominal cavity through the area of the stitched tissues is either completely prevented or drastically reduced.

5 Compared with the known, the proposed method for the prevention of infection of the abdominal cavity has the following advantages: it effectively suppresses the main source of infection of the abdominal cavity in the postoperative period — intraintestinal infection locally in the area of the operative wound of the intestine or stomach; provides the highest level of antimicrobial drugs in tissues in the area of the intestinal suture; completely prevents or dramatically reduces the infection of the abdominal cavity through the physically hermetical intestinal suture; not associated with negative effects of antimicrobial drugs; can be used for emergency gastrointestinal surgery; reduces the number of postoperative bacterial complications; reduces the time of treatment of patients after surgery.

Claims (1)

METHOD FOR PREVENTION OF INFRASTRUCTURE OF THE ABDOMINAL CAVITY IN OPERATIONS ON THE GASTROINTESTINAL TRACT by administering antibacterial agents, characterized in that, in order to prevent infection of the abdominal cavity, antibacterial agents ’are introduced into the intestinal suture in the intestinal lumen.