SU109660A1 - The method of replacing hydroxyl groups with fluorine in alcohols and their substituted - Google Patents
The method of replacing hydroxyl groups with fluorine in alcohols and their substitutedInfo
- Publication number
- SU109660A1 SU109660A1 SU555776A SU555776A SU109660A1 SU 109660 A1 SU109660 A1 SU 109660A1 SU 555776 A SU555776 A SU 555776A SU 555776 A SU555776 A SU 555776A SU 109660 A1 SU109660 A1 SU 109660A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- alcohols
- substituted
- fluorine
- hydroxyl groups
- replacing
- Prior art date
Links
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Известна реакци замены спиртового гидроксила на галоид с помощью галоидБодородных кислот или галоидангидридов сильных минеральных кислот, широко используема дл получени хлор-, броми иодпроизводных, дл синтеза, соответствующих фторорганических соединений, в частности, посредством фтористого водорода.The known reaction of replacing an alcoholic hydroxyl with a halogen with the help of halogen. Hydrogenic acids or acid halides of strong mineral acids, widely used for the preparation of chlorine, bromide and iodine derivatives, for the synthesis, of the corresponding organofluorine compounds, in particular, by means of hydrogen fluoride.
В описываемом изобретении предлагаетс способ замещени гидроксильной группы в алкогол х и их замещенных путем действи на алкоголи и их производные сульфофторидами в присутствии безводного фтористого кали дл получени р да фторорганических соединений и их замещенных.The invention provides a method for replacing a hydroxyl group in alcohols and their substituted by acting on alcohols and their derivatives with sulfofluorides in the presence of anhydrous potassium fluoride to obtain a variety of organofluorine compounds and their substituted ones.
Описанным способом были синтезированы с хорощим выходом фтористые метил- и ЭТИ.Л 1,2-дифторэтан и 1,2-фторхлорэтан.Methyl- and ETI fluorides were synthesized with a good yield in the described manner. L 1,2-difluoroethane and 1,2-fluorochloroethane.
Пример 1. 20 г метилового спирта, 80 г бензолсульфофторида и 58 г фтористого кали загружают в реактор, снабженный мещалкой и обратным холодильником . Смесь при непрерывном перемещивании нагревают при кипении в течение 7 часов. После очистки концентрированной H2SO. собирают более И г фтористого метила.Example 1. 20 g of methyl alcohol, 80 g of benzenesulfonate and 58 g of potassium fluoride are loaded into a reactor equipped with a blender and reflux condenser. The mixture with continuous moving is heated at boiling for 7 hours. After purification with concentrated H2SO4. collect more and r fluoride methyl.
Пример 2. 32 г этиленфторгидрина , 80 г бензолсульфофторида и 64 г прокаленного фтористого кали нагревают в колбе с дефлегматором при кипении. Дефлегматор через пр мой холодильник соедин ют с ловущкой, охлаждаемой льдом и приемником, помещенным в сосуд Дьюара. Полученное вещество 1,2-дифторэтан термически устойчиво .Example 2. 32 g of ethylene sulfonate, 80 g of benzenesulfonate and 64 g of calcined potassium fluoride is heated in a flask with a reflux condenser at boiling. A reflux condenser is connected through a direct cooler to an ice-cooled trap and receiver placed in a Dewar vessel. The resulting substance 1,2-difluoroethane is thermally stable.
Предмет изобретени Subject invention
Способ замещени гидроксильной группы на фтор в алкогол х и их замещенных, отличающийс тем, что на алкоголи или фторзамещенные алкоголей действуют одновременно бензолсульфофторидом и безводным фтористым калием.A method of replacing a hydroxyl group with fluorine in alcohols and their substituted ones, characterized in that alcohols or fluorine-substituted alcohols are simultaneously affected by benzenesulfofluoride and anhydrous potassium fluoride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU555776A SU109660A1 (en) | 1956-07-07 | 1956-07-07 | The method of replacing hydroxyl groups with fluorine in alcohols and their substituted |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU555776A SU109660A1 (en) | 1956-07-07 | 1956-07-07 | The method of replacing hydroxyl groups with fluorine in alcohols and their substituted |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU109660A1 true SU109660A1 (en) | 1956-11-30 |
Family
ID=48382670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU555776A SU109660A1 (en) | 1956-07-07 | 1956-07-07 | The method of replacing hydroxyl groups with fluorine in alcohols and their substituted |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU109660A1 (en) |
-
1956
- 1956-07-07 SU SU555776A patent/SU109660A1/en active
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